Drug Information

Drug General Information
Drug ID
D0W4HJ
Former ID
DIB007660
Drug Name
MSX-3
Synonyms
MSX-2
Drug Type
Small molecular drug
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Investigative [540979]
Company
Universitat Wurzburg
Structure
Download
2D MOL

3D MOL
Formula
C21H22N4O4
InChI
InChI=1S/C21H22N4O4/c1-4-11-25-20(27)18-19(24(21(25)28)12-6-13-26)22-17(23(18)2)10-9-15-7-5-8-16(14-15)29-3/h1,5,7-10,14,26H,6,11-13H2,2-3H3/b10-9+
InChIKey
FWLDDFYHEQMIGG-MDZDMXLPSA-N
CAS Number
CAS 261717-23-1
PubChem Compound ID
10046145
PubChem Substance ID
15029546, 22469057, 29217588, 44163197, 47510096, 47880130, 76455154, 103377967, 103984388, 138080087, 162247386, 178102244, 227935109, 252450802
Target and Pathway
Target(s) Adenosine A2a receptor Target Info Modulator [540978]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Parkinson's disease
Alcoholism
Pathway Interaction Database HIF-2-alpha transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
Reactome NGF-independant TRKA activation
Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
Monoamine Transport
GPCRs, Class A Rhodopsin-like
NGF signalling via TRKA from the plasma membrane
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540979(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5610).
Ref 540978(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5610).

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