Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0X5JS
|
||||
Former ID |
DAP001351
|
||||
Drug Name |
Barbituric acid
|
||||
Synonyms |
Barbiturate; Barbitursaeure; Malonylharnstoff; Malonylurea; Pyrimidinetriol; Pyrimidinetrione; Sodium barbiturate; Barbituric acid (VAN); AG-670/31547005; Barbituric acid (VAN) (8CI); Hexahydropyrimidine-2,4,6-trione; Hexahydro-pyrimidine-2,4,6-trione; Pyrimidine-2,4,6(1H,3H,5H)-trione; 1,2,3,4,5,6-Hexahydro-2,4,6-pyrimidinetrione; 1,3-diazinane-2,4,6-trione; 11709_FLUKA; 2,4,6(1H,3H,5H)-Pyrimidinetrione; 2,4,6-(1H,3H,5H)-Pyrimidinetrione; 2,4,6-Pyrimidinetriol; 2,4,6-Pyrimidinetrione; 2,4,6-Trihydroxypyrimidine; 2,4,6-Trioxohexahydropyrimidine; 6-Hydroxyuracil
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Depression [ICD9: 311; ICD10:F30-F39] | Approved | [536555] | ||
Therapeutic Class |
Antidepressants
|
||||
Structure |
Download2D MOL |
||||
Formula |
C4H4N2O3
|
||||
Canonical SMILES |
C1C(=O)NC(=O)NC1=O
|
||||
InChI |
1S/C4H4N2O3/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)
|
||||
InChIKey |
HNYOPLTXPVRDBG-UHFFFAOYSA-N
|
||||
CAS Number |
CAS 67-52-7
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
4071, 73654, 610615, 839197, 3137537, 3727084, 5630165, 8145676, 8153899, 10532462, 15461893, 24847314, 24851157, 29225209, 48413258, 49857195, 57323260, 57955591, 74498975, 85083143, 85165145, 85247090, 92298605, 103695223, 103811900, 104311418, 104837276, 117593533, 118081819, 124955112, 125308349, 125308617, 125355973, 126546422, 126677922, 127279485, 127279486, 127279487, 127341845, 127341846, 127354639, 131269178, 131323285, 134338565, 134338658, 134970720, 135605431, 136292137, 137006791, 141968478
|
||||
ChEBI ID |
ChEBI:16294
|
||||
Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Antagonist | [536555], [537688] | |
References | |||||
Ref 536555 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29. | ||||
Ref 537688 | Effect of barbiturates on polyphosphoinositide biosynthesis and protein kinase C activity in synaptosomes. Neuropharmacology. 1989 Dec;28(12):1317-23. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.