Drug General Information
Drug ID
D0Z8IJ
Former ID
DNC000971
Drug Name
Muscimol
Drug Type
Small molecular drug
Indication Discovery agent Phase 1 [1], [2]
Structure
Download
2D MOL

3D MOL

Formula
C4H6N2O2
InChI
InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
InChIKey
ZJQHPWUVQPJPQT-UHFFFAOYSA-N
CAS Number
CAS 94421-68-8
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:2700
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Agonist [3]
Glutamate receptor AMPA subtype Target Info Agonist [4]
References
REF 1(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4259).
REF 2ClinicalTrials.gov (NCT00921128) Convection-Enhanced Delivery to Study the Pathophysiology Underlying the Clinical Features of Parkinson s Disease. U.S. National Institutes of Health.
REF 3THIP treatment of Huntington's disease. Neurology. 1983 May;33(5):637-9.
REF 4GABA(A) receptor ligands and their therapeutic potentials. Curr Top Med Chem. 2002 Aug;2(8):817-32.

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