Drug Information

Drug General Information
Drug ID
D0C6KQ
Former ID
DNC012485
Drug Name
IODOSULPIRIDE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533883]
Structure
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2D MOL

3D MOL
Formula
C15H22IN3O4S
Canonical SMILES
CCN1CCCC1CNC(=O)C2=C(C=CC(=C2I)S(=O)(=O)N)OC
InChI
1S/C15H22IN3O4S/c1-3-19-8-4-5-10(19)9-18-15(20)13-11(23-2)6-7-12(14(13)16)24(17,21)22/h6-7,10H,3-5,8-9H2,1-2H3,(H,18,20)(H2,17,21,22)/t10-/m0/s1
InChIKey
HCKMONAVUWHQOT-JTQLQIEISA-N
PubChem Compound ID
44312731
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Inhibitor [533883]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 533883J Med Chem. 1993 Jan 22;36(2):221-8.Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.
Ref 533883J Med Chem. 1993 Jan 22;36(2):221-8.Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.

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