Drug Information

Drug General Information
Drug ID
D0I7VY
Former ID
DIB020876
Drug Name
RY796
Synonyms
RY 796; RY-796
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542716]
Structure
Download
2D MOL
Formula
C21H27N3O2
InChI
InChI=1S/C21H27N3O2/c1-14(2)20(25)23-17-11-12-19(24(4)5)18(13-17)21(26)22-15(3)16-9-7-6-8-10-16/h6-15H,1-5H3,(H,22,26)(H,23,25)/t15-/m1/s1
InChIKey
LDXZFQWWXMRMAS-OAHLLOKOSA-N
PubChem Compound ID
76850157
PubChem Substance ID
196376759, 223366092
Target and Pathway
Target(s) Kv2.2 Target Info Inhibitor (gating inhibitor) [531634]
Potassium voltage-gated channel subfamily B member 1 Target Info Inhibitor (gating inhibitor) [531634]
Reactome Voltage gated Potassium channels
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
WikiPathways Calcium Regulation in the Cardiac Cell
Potassium Channels
References
Ref 542716(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7759).
Ref 531634Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64.

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