Drug Information
Drug General Information | |||||
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Drug ID |
D0Q2LG
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Former ID |
DIB018671
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Drug Name |
5S-HPETE
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Synonyms |
5-(S)-hydroperoxyeicosatetraenoic acid; 5S-HpETE
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539608] | ||
Structure |
Download2D MOL |
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Formula |
C20H32O4
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InChI |
InChI=1S/C20H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(24-23)17-15-18-20(21)22/h6-7,9-10,12-14,16,19,23H,2-5,8,11,15,17-18H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1
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InChIKey |
JNUUNUQHXIOFDA-JGKLHWIESA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
7733, 4266118, 8143290, 8616390, 15988963, 26754757, 26754758, 39289806, 47515057, 48258936, 49964840, 50110770, 53801093, 57357866, 80066874, 92309861, 99300775, 99302293, 104046397, 113853964, 126523872, 131279964, 135151068, 142970203, 162226029, 179205513, 227610724, 250132992, 252455585, 252465547
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Target and Pathway | |||||
Target(s) | OXE receptor | Target Info | Agonist | [527658] | |
Vanilloid receptor 1 | Target Info | Activator | [525777] | ||
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References | |||||
Ref 525777 | Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6155-60. | ||||
Ref 527658 | TG1019/OXE, a Galpha(i/o)-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis. Biochem Biophys Res Commun. 2005 Sep 9;334(4):987-95. |
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