Drug General Information
Drug ID
D03LLM
Former ID
DIB020959
Drug Name
SLG
Synonyms
1-stearoyl-2-linoleoyl-sn-glycerol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539570]
Structure
Download
2D MOL
Formula
C39H72O5
InChI
InChI=1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h12,14,18,20,37,40H,3-11,13,15-17,19,21-36H2,1-2H3/b14-12-,20-18-/t37-/m0/s1
InChIKey
AJMZUFBKADIAKC-SKTOPKGQSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Short transient receptor potential channel 6 Target Info Activator [534828]
PANTHER Pathway Alzheimer disease-presenilin pathway
Pathway Interaction Database Endothelins
Nephrin/Neph1 signaling in the kidney podocyte
EPO signaling pathway
PAR1-mediated thrombin signaling events
Reactome Effects of PIP2 hydrolysis
TRP channels
Role of second messengers in netrin-1 signaling
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
Platelet homeostasis
Netrin-1 signaling
GPCR downstream signaling
Effects of PIP2 hydrolysis
References
Ref 539570(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2442).
Ref 534828Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63.

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