Drug Information
Drug General Information | |||||
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Drug ID |
D0M3KZ
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Former ID |
DIB020482
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Drug Name |
NAD
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Synonyms |
NAD+
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539580] | ||
Structure |
Download2D MOL |
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Formula |
C21H27N7O14P2
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InChI |
InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
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InChIKey |
BAWFJGJZGIEFAR-NNYOXOHSSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
841105, 7836298, 7885587, 7889144, 7889277, 8149434, 8153645, 14790299, 14912780, 26611829, 26681097, 26697181, 29224919, 49699158, 50033280, 50123523, 50123524, 53787893, 57323025, 57551970, 77064053, 87567516, 91011349, 92298062, 92307336, 99301277, 104250768, 104310545, 121363359, 124637933, 134971502, 135364879, 135651521, 135692504, 137241347, 144075133, 144203872, 152031738, 160810701, 162038182, 162180452, 163088706, 172097172, 179210308, 183213584, 204379330, 210279594, 210281917, 226500313, 250133618
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Target and Pathway | |||||
Target(s) | Long transient receptor potential channel 2 | Target Info | Activator | [526528] | |
P2Y11 receptor | Target Info | Agonist | [528388] | ||
Reactome | TRP channels | ||||
References | |||||
Ref 526528 | Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD. Biochem J. 2003 May 1;371(Pt 3):1045-53. | ||||
Ref 528388 | Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes. J Biol Chem. 2006 Oct 20;281(42):31419-29. Epub 2006 Aug 22. |
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