Drug Information
Drug General Information | |||||
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Drug ID |
D0RF2M
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Former ID |
DNC005811
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Drug Name |
NIPECOTIC ACID
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [467801] | ||
Structure |
Download2D MOL |
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Formula |
C6H11NO2
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InChI |
InChI=1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)
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InChIKey |
XJLSEXAGTJCILF-UHFFFAOYSA-N
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CAS Number |
CAS 498-95-3
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PubChem Compound ID | |||||
PubChem Substance ID |
3138351, 7404102, 8139863, 8150178, 8152771, 11335323, 11360562, 11363247, 11365809, 11368371, 11372643, 11373796, 11376533, 11461534, 11466978, 11468098, 11484963, 11486815, 11489000, 11491527, 11491984, 11494167, 15170656, 17404605, 24278161, 26613203, 26679237, 26747103, 29223592, 35033299, 47213193, 47216644, 47440115, 47440116, 47736328, 47810612, 47810613, 47885272, 48034968, 48110317, 48184862, 49698820, 49833219, 50015592, 50104354, 50104355, 50104356, 50396592, 53777147, 57322300
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Target and Pathway | |||||
Target(s) | Sodium- and chloride-dependent GABA transporter 1 | Target Info | Inhibitor | [533538] | |
GABA transporter-3 | Target Info | Inhibitor | [533538] | ||
4-aminobutyrate aminotransferase, mitochondrial | Target Info | Inhibitor | [533540] | ||
Adenosine A3 receptor | Target Info | Inhibitor | [527823] | ||
Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [533396] | ||
References | |||||
Ref 527823 | J Med Chem. 2005 Nov 3;48(22):6887-96.2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization. | ||||
Ref 533396 | J Med Chem. 1985 May;28(5):653-60.Orally active and potent inhibitors of gamma-aminobutyric acid uptake. | ||||
Ref 533538 | J Med Chem. 1981 Jul;24(7):788-94.Epimeric cis-decahydroquinoline-5-carboxylic acids: effects on gamma-aminobutyric acid uptake and receptor binding in vitro. | ||||
Ref 533540 | J Med Chem. 1982 Feb;25(2):113-6.Aminomethyl-1,2,4-benzothiadiazines as potential analogues of gamma-aminobutyric acid. Unexpected discovery of a taurine antagonist. |
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