Drug Information
Drug General Information | |||||
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Drug ID |
D0T6DU
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Former ID |
DIB020589
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Drug Name |
OAG
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Synonyms |
1-oleoyl-2-acetyl-sn-glycerol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539564] | ||
Structure |
Download2D MOL |
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Formula |
C23H42O5
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InChI |
InChI=1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10+
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InChIKey |
PWTCCMJTPHCGMS-ZHACJKMWSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Short transient receptor potential channel 3 | Target Info | Activator | [534828] | |
Short transient receptor potential channel 6 | Target Info | Activator | [534828] | ||
TRPC2 | Target Info | Activator | [526896] | ||
TRPC7 | Target Info | Activator | [525586] | ||
PANTHER Pathway | Alzheimer disease-presenilin pathway | ||||
References | |||||
Ref 525586 | Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. J Biol Chem. 1999 Sep 24;274(39):27359-70. | ||||
Ref 526896 | A diacylglycerol-gated cation channel in vomeronasal neuron dendrites is impaired in TRPC2 mutant mice: mechanism of pheromone transduction. Neuron. 2003 Oct 30;40(3):551-61. | ||||
Ref 534828 | Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63. |
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