Drug Information
Drug General Information | |||||
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Drug ID |
D07CJR
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Former ID |
DIB018670
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Drug Name |
5S-HETE
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Synonyms |
5-(S)-hydroxyeicosatetraenoic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540338] | ||
Structure |
Download2D MOL |
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Formula |
C20H32O3
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InChI |
InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h6-7,9-10,12-14,16,19,21H,2-5,8,11,15,17-18H2,1H3,(H,22,23)/b7-6-,10-9-,13-12-,16-14+/t19-/m1/s1
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InChIKey |
KGIJOOYOSFUGPC-JGKLHWIESA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
7367, 4266109, 8616380, 14717639, 15469964, 26754739, 26754740, 39289780, 47290863, 47364900, 47364901, 49964846, 50110766, 53788764, 57357855, 77570786, 92309859, 99300773, 99302291, 103419145, 103936995, 104046382, 113853892, 126529724, 134339618, 135111503, 135651416, 137008431, 142970226, 164789588, 179205486, 184568140, 227683983, 249492905, 252371371, 252455583, 252465535
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Target and Pathway | |||||
Target(s) | OXE receptor | Target Info | Agonist | [527658] | |
Vanilloid receptor 1 | Target Info | Activator | [543861] | ||
NetPath Pathway | IL2 Signaling Pathway | ||||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | ||||
Trk receptor signaling mediated by PI3K and PLC-gamma | |||||
Reactome | TRP channels | ||||
References | |||||
Ref 527658 | TG1019/OXE, a Galpha(i/o)-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis. Biochem Biophys Res Commun. 2005 Sep 9;334(4):987-95. | ||||
Ref 543861 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 507). |
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