Drug Information
Drug General Information | |||||
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Drug ID |
D0X5XU
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Former ID |
DAP000641
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Drug Name |
Decitabine
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Synonyms |
AzadC; Dacogen; Dezocitidine; NCGC_5ADOC; Dacogen (TN); E-7373; Decitabine (USAN/INN); Dacogen, 5-aza-2'-deoxycytidine,NSC 127716, Dacogen, DAC, Decitabine; 2'-Deoxy-5-azacytidine; 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one; 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one; 4-Amino-1-(2-deoxy-beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one; 5-AZAdC; 5-Aza-2′-Deoxycytidine; 5-Aza-2'-deoxycytidine; 5-Azadeoxycytidine; 5-Deoxy-2′-azacytidine; 5-aza-2-deoxycytidine; 5-aza-CdR; 5-aza-dC; 5A2dc
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Structure |
Download2D MOL |
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Formula |
C8H12N4O4
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InChI |
InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1
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InChIKey |
XAUDJQYHKZQPEU-KVQBGUIXSA-N
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CAS Number |
CAS 2353-33-5
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PubChem Compound ID | |||||
PubChem Substance ID |
596457, 10300747, 12013916, 14749266, 14798099, 17397761, 24890797, 26758275, 46505657, 47211573, 47515034, 48422583, 49831907, 49836662, 53789316, 56310803, 56310829, 56310991, 56311079, 56311138, 56311371, 56311372, 56311435, 56311466, 56311472, 56311487, 56311581, 56311739, 56311918, 56312280, 56312302, 56312939, 56313048, 56313052, 56313366, 56313487, 56313832, 56313833, 56313869, 56314010, 56324652, 57260149, 57288417, 57288447, 57288645, 57405281, 78597402, 92719107, 103771112, 104253166
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ChEBI ID |
ChEBI:50131
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SuperDrug ATC ID |
L01BC08
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Target and Pathway | |||||
Target(s) | Human DNA | Target Info | Modulator | [528715] | |
References | |||||
Ref 528715 | 2006 drug approvals: finding the niche. Nat Rev Drug Discov. 2007 Feb;6(2):99-101. | ||||
Ref 541887 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6805). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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