Drug Information

Drug General Information
Drug ID
D0G6XC
Former ID
DIB010946
Drug Name
SW-33377
Synonyms
SR-233377; Win-33377; N-[1-[2-(Diethylamino)ethylamino]-9-oxothioxanthen-4-ylmethyl]methanesulfonamide; 1-[2-(Diethylamino)ethylamino]-4-(methanesulfonamidomethyl)thioxanthen-9-one
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Discontinued in Phase 1 [545413]
Structure
Download
2D MOL

3D MOL
Formula
C21H27N3O3S2
Canonical SMILES
CCN(CC)CCNC1=C2C(=C(C=C1)CNS(=O)(=O)C)SC3=CC=CC=C3C2=O
InChI
1S/C21H27N3O3S2/c1-4-24(5-2)13-12-22-17-11-10-15(14-23-29(3,26)27)21-19(17)20(25)16-8-6-7-9-18(16)28-21/h6-11,22-23H,4-5,12-14H2,1-3H3
InChIKey
NAMOLZVVTPNNTE-UHFFFAOYSA-N
CAS Number
CAS 146537-07-7
PubChem Compound ID
3035776
PubChem Substance ID
10048437, 14881062, 36079162, 57353237, 78994374, 103198386, 103961331, 111639726, 128674330, 135082519, 143160498, 198947711, 226971973
Target and Pathway
Target(s) Human DNA Target Info Binder [525510]
References
Ref 545413Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003155)
Ref 525510Effects of SW 33377, SW 68210 and SW 71425 thioxanthones on in vitro colony formation of freshly explanted human tumor cells. Invest New Drugs. 1998-1999;16(3):221-5.

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