Drug Information

Drug General Information
Drug ID
D0AX1N
Former ID
DCL001046
Drug Name
OGX-427
Drug Type
Antisense drug
Indication Breast cancer; Ovarian cancer; Bladder cancer; Prostate cancer; Lung cancer [ICD9: 140-229, 162, 183, 188; ICD10:C00-C96, C33-C34, C56, C67] Phase 2 [525165]
Therapeutic Class
Antisense
Company
Isis Pharmaceuticals & OncoGenex
Formula
C224H304N79O116P19S19
PubChem Compound ID
71710946
Target and Pathway
Target(s) Heat shock protein 27 Target Info Modulator [1572591]
References
Ref 525165ClinicalTrials.gov (NCT02423590) Study of Gemcitabine/Carboplatin First-line Chemotherapy +/- Apatorsen in Advanced Squamous Cell Lung Cancers. U.S. National Institutes of Health.
Ref 1572591Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.

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