Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T17721
|
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| Former ID |
TTDI03319
|
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| Target Name |
Kir3.2
|
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| Gene Name |
KCNJ6
|
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| Synonyms |
KCNJ6
|
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| Target Type |
Research
|
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| UniProt ID | |||||
| Sequence |
MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKD
GKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGD MDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSI VNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAK LIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKE ELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYET STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENE SKV |
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| Inhibitor (gating inhibitor) | F3 | Drug Info | [1] | ||
| Activator | PIP2 | Drug Info | [2] | ||
| References | |||||
| REF 1 | Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. Anesthesiology. 2001 Jul;95(1):144-53. | ||||
| REF 2 | Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. Nature. 1998 Feb 19;391(6669):803-6. | ||||
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