Target Information
Target General Infomation | |||||
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Target ID |
T58298
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Former ID |
TTDR00537
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Target Name |
Ectonucleoside triphosphate diphosphohydrolase 1
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Gene Name |
ENTPD1
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Synonyms |
ATPDase; CD39 antigen; Ecto-ATP diphosphohydrolase; Ecto-apyrase; Ecto-nucleotidase CD-39; Lymphoid cell activation antigen; NTPDase1; ENTPD1
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Target Type |
Research
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Function |
In the nervous system, could hydrolyze atp and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes atp and adp equally well.
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BioChemical Class |
Acid anhydrides hydrolase
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Target Validation |
T58298
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UniProt ID | |||||
EC Number |
EC 3.6.1.5
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Sequence |
MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHT
SLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQ HQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWI TINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFR LYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTP CTKRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAF SAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYIL SLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFL MVLFSLVLFTVAIIGLLIFHKPSYFWKDMV |
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Pathways | |||||
BioCyc Pathway | UTP and CTP dephosphorylation II | ||||
KEGG Pathway | Purine metabolism | ||||
Pyrimidine metabolism | |||||
Epstein-Barr virus infection | |||||
References |
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