Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| 5HT1a --- SERT | 4-{(S)-2-Hydroxy-3-[(1R,3S,5S)-3-(4-methoxy-benzo[b]thiophen-2-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propoxy}-1H-indole-2-carboxylic acid amide | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-((2S,4R)-4-(benzo[b]thiophen-2-yl)-2-methylpiperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[(4S,6R)-4-(4,6-Dimethyl-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 6-((1-(2-(6-fluoro-2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | Drug Info |
| 5HT1a --- SERT | 6-((1-(2-(7-chloro-2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | Drug Info |
| 5HT1a --- SERT | 6-{2-[2-Hydroxy-3-(1H-indol-4-yloxy)-propylamino]-propoxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(Quinolin-8-yloxy)-ethyl]-piperidin-4-yloxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-((2S,4S)-4-(4-methoxybenzo[b]thiophen-2-yl)-2-methylpiperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[(2S,4R)-4-(4,6-Dimethyl-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(2-Methyl-1H-indol-4-yloxy)-3-[(2S,4R)-2-methyl-4-(4-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-((2S,4R)-4-(5-fluorobenzo[b]thiophen-2-yl)-2-methylpiperidin-1-yl)-3-(2-methyl-1H-indol-4-yloxy)propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-(4-(4-methoxybenzo[b]thiophen-2-yl)piperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(2-Methyl-quinolin-5-yloxy)-ethyl]-piperidin-4-ylmethyl}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1a --- SERT | 2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine | Drug Info |
| 5HT1a --- SERT | (S)-1-[(1R,3S,5S)-3-(4-Methoxy-benzo[b]thiophen-2-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[4-(3-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[(4S,6R)-4-(6-Chloro-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[4-(6-Chloro-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-fluorophenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | 2-{1-[(S)-2-Hydroxy-3-(1H-indol-4-yloxy)-propyl]-piperidin-4-yl}-benzo[b]thiophen-7-ol | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(Isoquinolin-1-yloxy)-ethyl]-piperidin-4-yloxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methoxy-benzo[b]thiophen-2-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-(4-(6-fluorobenzo[b]thiophen-2-yl)piperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | 2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-8-methoxy-4-propyl-3,4-dihydro-2H-benzo[b][1,4]oxazine | Drug Info |
| 5HT1a --- SERT | (S)-1-[4-(5-Chloro-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 1-(biphenyl-4-yl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propan-1-ol | Drug Info |
| 5HT1a --- SERT | 3-(4-(2-chlorophenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | 4-{(S)-2-Hydroxy-3-[(2R,4R)-4-(4-methoxy-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-propoxy}-1H-indole-2-carboxylic acid amide | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[4-(6-isopropoxy-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[(2S,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-chlorophenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[4-(6-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 1-(4-methoxyphenyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propan-1-ol | Drug Info |
| 5HT1a --- SERT | [3-(5-Fluoro-1H-indol-3-yl)-propyl]-[2-(1H-indol-4-yloxy)-ethyl]-amine | Drug Info |
| 5HT1a --- SERT | 3-{Cyclobutyl[3-(6-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide | Drug Info |
| 5HT1a --- SERT | 3-(4-(4-methoxyphenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | 1-(4-methoxyphenyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propan-1-one | Drug Info |
| 5HT1a --- SERT | (S)-1-[4-(4-Methoxy-benzo[b]thiophen-2-yl)-2,2-dimethyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 1-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)propan-1-one | Drug Info |
| 5HT1a --- SERT | [3-(1H-Indol-3-yl)-propyl]-[2-(naphthalen-1-yloxy)-ethyl]-amine | Drug Info |
| 5HT1a --- SERT | (S)-1-[(2S,4R)-4-(5-Chloro-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-((2S,4R)-4-(6-methoxybenzo[b]thiophen-2-yl)-2-methylpiperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | 6-((1-(2-(8-chloro-2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | Drug Info |
| 5HT1a --- SERT | 3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylpropan-1-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-Indol-4-yloxy)-3-[4-(6-methoxy-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-[4-(5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-phenyl-propan-1-one oxime | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(Naphthalen-1-yloxy)-ethyl]-piperidin-4-yloxy}-4H-benzo[1,4]oxazin-3-one | Drug Info |
| 5HT1a --- SERT | (S)-1-[(2R,4S)-4-(4-Methoxy-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-benzofuran-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | 6-{1-[2-(Quinolin-5-yloxy)-ethyl]-piperidin-4-ylmethyl}-4H-benzo[1,4]oxazin-3-one | Drug Info |
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