Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| AuroraA --- STK1 | N-Cyclopropyl-4-(5-fluoro-2-(4-hydroxyphenylamino)pyrimidin-4-ylamino)benzamide | Drug Info |
| AuroraA --- STK1 | N-Ethyl-N'-[4-(1-ethyl-4-{2-[4-(1-pyrrolidinylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1H-pyrazol-3-yl)phenyl]urea | Drug Info |
| AuroraA --- STK1 | 1-(3-chloro-4-fluorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | CHEMBL381724 | Drug Info |
| AuroraA --- STK1 | N-(6-methyl-3-styryl-1H-indazol-5-yl)-2-(thiophen-2-yl)acetamide | Drug Info |
| AuroraA --- STK1 | N-ethyl-4-((5-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-ylamino)isothiazol-3-yl)methyl)piperazine-1-carboxamide | Drug Info |
| AuroraA --- STK1 | 1-cyclohexyl-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | N-[3-(dimethylamino)phenyl]-2-{2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetamide | Drug Info |
| AuroraA --- STK1 | (Z)-N-[3-({3-[3-(Diethylamino)propyl]-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl}methylene)-2-oxoindolin-5-yl]benzenesulfonamide | Drug Info |
| AuroraA --- STK1 | (Z)-3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)indolin-3-ylidene]-methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid | Drug Info |
| AuroraA --- STK1 | 4-(2-(4-(2-(4-Acetylpiperazin-1-yl)-2-oxoethyl)phenylamino)-5-fluoropyrimidin-4-ylamino)-N-(2-chlorophenyl)benzamide | Drug Info |
| AuroraA --- STK1 | 1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfonamide | Drug Info |
| AuroraA --- STK1 | ZM-447439 | Drug Info |
| AuroraA --- STK1 | N,N-dimethyl-1-(3-(4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)methanamine | Drug Info |
| AuroraA --- STK1 | CHEMBL201297 | Drug Info |
| AuroraA --- STK1 | N-{4-[1-(2,3-Dihydroxypropyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}-N'-phenylurea | Drug Info |
| AuroraA --- STK1 | (Z)-3-(2-{[5-(Indolin-1-ylsulfonyl)-2-oxoindolin-3-ylidene]-methyl}-4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid | Drug Info |
| AuroraA --- STK1 | 2-[({2-[(7-{3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetyl)amino]benzamide | Drug Info |
| AuroraA --- STK1 | N-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-(1-(methylsulfonyl)piperidin-4-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-(pyridin-3-yl)pyrimidin-2-ylthio)phenyl)propionamide | Drug Info |
| AuroraA --- STK1 | N-{4-[1-(3-Hydroxypropyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}-N'-phenylurea | Drug Info |
| AuroraA --- STK1 | (Z)-N-Methyl-3-(4-oxo-2-{[2-oxo-5-(phenylsulfonamido)-indolin-3-ylidene]methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)-propanamide | Drug Info |
| AuroraA --- STK1 | (R)-4-(4-methylpiperazin-1-yl)-N-(5-(2-phenylpropanoyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)benzamide | Drug Info |
| AuroraA --- STK1 | tert-butyl 4-(4-(5-methyl-1H-pyrazol-3-ylamino)quinazolin-2-ylthio)phenylcarbamate | Drug Info |
| AuroraA --- STK1 | (S)-4-(2-amino-6-(3-amino-1H-indazol-6-yl)pyrimidin-4-yl)-N-phenylmorpholine-2-carboxamide | Drug Info |
| AuroraA --- STK1 | Deuterated 6-Methyl-3-(1H-pyrazol-4-tl)-N-[3-[[(3,3,3-trifluoropropyl)amino]methyl-(d2)]-5-isothiazolyl]imidazo[1,2-a]pyrazin-8-amine Hydrochloride | Drug Info |
| AuroraA --- STK1 | 3-((2,2-dimethylpiperidin-1-yl)methyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 4-methyl-N-(3-(2-(5-(methylsulfonamido)-6-(pyrrolidin-1-yl)-1H-indazol-3-yl)vinyl)phenyl)piperazine-1-carboxamide | Drug Info |
| AuroraA --- STK1 | CHEMBL385049 | Drug Info |
| AuroraA --- STK1 | N-(2-(2-(1H-benzo[d]imidazol-2-ylamino)thiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | (3S,6R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide | Drug Info |
| AuroraA --- STK1 | (Z)-3-(2-{[5-(N,N-Dimethylsulfamoyl)-2-oxoindolin-3-ylidene]-methyl}-4-oxo-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid | Drug Info |
| AuroraA --- STK1 | 4-(5-Methyl-1H-pyrazol-3-ylamino)-2-(4-nitrobenzyl)-2Hphthalazin-1-one | Drug Info |
| AuroraA --- STK1 | N-2-fluorophenyl-2-3-7-3-4-hydroxymethyl-piperidin-1-yl-propoxy-6-methoxyquinazolin-4-ylamino-1H-pyrazol-5-yl-acetamide | Drug Info |
| AuroraA --- STK1 | N-(3-fluorophenyl)-2-{2-[(7-{2-[4-(hydroxyethyl)piperidin-1-yl]ethoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetamide | Drug Info |
| AuroraA --- STK1 | 2-(6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-ylamino)-N-phenylthiazole-5-carboxamide | Drug Info |
| AuroraA --- STK1 | N-(5-butyl-1,3-thiazol-2-yl)-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-amine | Drug Info |
| AuroraA --- STK1 | CHEMBL382054 | Drug Info |
| AuroraA --- STK1 | N-(6-(tert-butylthio)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-(Phenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo-[2,3-b]pyridin-2-yl]phenyl}acetamide | Drug Info |
| AuroraA --- STK1 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-phenylpyrimidin-2-ylthio)phenyl)propionamide | Drug Info |
| AuroraA --- STK1 | 6-Methyl-N-[3-(1-piperidinylmethyl)-5-isothiazolyl]-3-(1Hpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine Hydrochloride | Drug Info |
| AuroraA --- STK1 | 4-[1-Ethyl-3-(4-{[(phenylamino)carbonyl]amino}phenyl)-1Hpyrazol-4-yl]-N-[2-(4-morpholinyl)ethyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | Drug Info |
| AuroraA --- STK1 | 7,7-Dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-6-oxo-1H-imidazo[4,5-f]indole | Drug Info |
| AuroraA --- STK1 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine | Drug Info |
| AuroraA --- STK1 | N-(4-(4-(4-tert-butylpiperazin-1-yl)-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-ylthio)phenyl)propionamide | Drug Info |
| AuroraA --- STK1 | N-(6-methyl-3-(phenylethynyl)-1H-indazol-5-yl)-2-(thiophen-2-yl)acetamide | Drug Info |
| AuroraA --- STK1 | N-(4-(6-chloro-3H-imidazo[4,5-b]pyridin-2-ylamino)phenethyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| AuroraA --- STK1 | N-(6-(2-aminoethyl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | N-Phenyl-N'-{4-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}urea | Drug Info |
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