Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T32060 | Target Info | |||
| Target Name | 5-HT 2A receptor (HTR2A) | ||||
| Synonyms |
Serotonin receptor 2A; HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2A; 5-HT-2
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| Target Type | Successful Target | ||||
| Gene Name | HTR2A | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Dopamine D2 receptor (D2R) | Successful Target | ||||
| UniProt ID | DRD2_HUMAN | |||||
| Gene Name | DRD2 | |||||
| Synonyms |
Dopamine receptor 2; D(2) dopamine receptor
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| Representative Drug(s) | Blonanserin | Drug Info | Ki = 0.14 nM | Click to Show More | [1] | |
| 2 | Aripiprazole | Drug Info | Ki = 0.2 nM | [2] | ||
| 3 | ZOTEPINE | Drug Info | Ki = 11 nM | [5] | ||
| 4 | Iloperidone | Drug Info | IC50 = 110 nM | [16] | ||
| Co-Target Name | 5-HT 2B receptor (HTR2B) | Successful Target | ||||
| UniProt ID | 5HT2B_HUMAN | |||||
| Gene Name | HTR2B | |||||
| Synonyms |
Serotonin receptor 2B; 5-hydroxytryptamine receptor 2B; 5-HT2B; 5-HT-2B; 5-HT 2B
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 0.36 nM | [3] | ||
| Co-Target Name | 5-HT 2C receptor (HTR2C) | Successful Target | ||||
| UniProt ID | 5HT2C_HUMAN | |||||
| Gene Name | HTR2C | |||||
| Synonyms |
Serotonin receptor 2C; HTR1C; 5HT-1C; 5-hydroxytryptamine receptor 2C; 5-hydroxytryptamine receptor 1C; 5-HTR2C; 5-HT2C receptor; 5-HT2C; 5-HT1C; 5-HT-2C; 5-HT-1C
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| Representative Drug(s) | Metergolin | Drug Info | Ki = 0.5 nM | Click to Show More | [4] | |
| 2 | ZOTEPINE | Drug Info | Ki = 2.9 nM | [10] | ||
| 3 | M100907 | Drug Info | Ki = 13 nM | [12] | ||
| 4 | Aripiprazole | Drug Info | Ki = 22 nM | [13] | ||
| 5 | TRYPTAMINE | Drug Info | Ki = 50 nM | [4] | ||
| 6 | NELOTANSERIN | Drug Info | Ki = 110 nM | [18] | ||
| 7 | PRUVANSERIN | Drug Info | Ki = 645 nM | [18] | ||
| Co-Target Name | Histamine H1 receptor (H1R) | Successful Target | ||||
| UniProt ID | HRH1_HUMAN | |||||
| Gene Name | HRH1 | |||||
| Synonyms |
HH1R; H1R
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| Representative Drug(s) | ZOTEPINE | Drug Info | Ki = 0.62 nM | Click to Show More | [5] | |
| 2 | Aripiprazole | Drug Info | Ki = 25.1 nM | [3] | ||
| 3 | M100907 | Drug Info | Ki = 1000 nM | [24] | ||
| Co-Target Name | Serotonin transporter (SERT) | Successful Target | ||||
| UniProt ID | SC6A4_HUMAN | |||||
| Gene Name | SLC6A4 | |||||
| Synonyms |
Solute carrier family 6 member 4; HTT; 5HTT; 5HT transporter
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| Representative Drug(s) | METHYLENEDIOXYMETHAMPHETAMINE | Drug Info | Ki = 0.73 nM | Click to Show More | [6] | |
| 2 | Aripiprazole | Drug Info | Ki = 31.62 nM | [15] | ||
| Co-Target Name | Dopamine D3 receptor (D3R) | Successful Target | ||||
| UniProt ID | DRD3_HUMAN | |||||
| Gene Name | DRD3 | |||||
| Synonyms |
D(3) dopamine receptor
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 1 nM | Click to Show More | [7] | |
| 2 | Abaperidone | Drug Info | Ki = 5.4 nM | [11] | ||
| 3 | ZOTEPINE | Drug Info | Ki = 6.4 nM | [5] | ||
| Co-Target Name | 5-HT 1A receptor (HTR1A) | Successful Target | ||||
| UniProt ID | 5HT1A_HUMAN | |||||
| Gene Name | HTR1A | |||||
| Synonyms |
Serotonin receptor 1A; G-21; ADRBRL1; ADRB2RL1; 5-hydroxytryptamine receptor 1A; 5-HT1A receptor; 5-HT1A; 5-HT-1A
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 1.7 nM | Click to Show More | [8] | |
| 2 | Metergolin | Drug Info | Ki = 2.3 nM | [9] | ||
| 3 | ZOTEPINE | Drug Info | Ki = 330 nM | [5] | ||
| 4 | Flibanserin | Drug Info | EC50 = 630.96 nM | [22] | ||
| Co-Target Name | 5-HT 1D receptor (HTR1D) | Successful Target | ||||
| UniProt ID | 5HT1D_HUMAN | |||||
| Gene Name | HTR1D | |||||
| Synonyms |
Serotonin receptor 1D; Serotonin 1D alpha receptor; HTRL; HTR1DA; 5HT1D; 5-hydroxytryptamine receptor 1D; 5-HT1D receptor; 5-HT1D; 5-HT-1D-alpha; 5-HT-1D
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| Representative Drug(s) | TRYPTAMINE | Drug Info | Ki = 23 nM | Click to Show More | [14] | |
| 2 | Aripiprazole | Drug Info | Ki = 100 nM | [17] | ||
| Co-Target Name | Dopamine D1 receptor (D1R) | Successful Target | ||||
| UniProt ID | DRD1_HUMAN | |||||
| Gene Name | DRD1 | |||||
| Synonyms |
D(1A) dopamine receptor
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| Representative Drug(s) | ZOTEPINE | Drug Info | Ki = 29 nM | Click to Show More | [5] | |
| 2 | Aripiprazole | Drug Info | Ki = 310 nM | [19] | ||
| Co-Target Name | 5-HT 1B receptor (HTR1B) | Successful Target | ||||
| UniProt ID | 5HT1B_HUMAN | |||||
| Gene Name | HTR1B | |||||
| Synonyms |
Serotonin receptor 1B; Serotonin 1D beta receptor; S12; HTR1DB; 5-hydroxytryptamine receptor 1B; 5-HT1B receptor; 5-HT1B; 5-HT-1D-beta; 5-HT-1B
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| Representative Drug(s) | TRYPTAMINE | Drug Info | Ki = 36 nM | Click to Show More | [14] | |
| 2 | Aripiprazole | Drug Info | Ki = 1000 nM | [17] | ||
| Co-Target Name | Dopamine D4 receptor (D4R) | Successful Target | ||||
| UniProt ID | DRD4_HUMAN | |||||
| Gene Name | DRD4 | |||||
| Synonyms |
DRD4; D(2C)D(4) dopamine receptor dopamine receptor
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| Representative Drug(s) | ZOTEPINE | Drug Info | Ki = 39 nM | Click to Show More | [5] | |
| 2 | Aripiprazole | Drug Info | Ki = 57.1 nM | [7] | ||
| 3 | Abaperidone | Drug Info | Ki = 179 nM | [11] | ||
| Co-Target Name | Opioid receptor sigma 1 (OPRS1) | Successful Target | ||||
| UniProt ID | SGMR1_HUMAN | |||||
| Gene Name | SIGMAR1 | |||||
| Synonyms |
hSigmaR1; Sigma1R; Sigma1-receptor; Sigma non-opioid intracellular receptor 1; Sigma 1-type opioid receptor; SRBP; SR31747-binding protein; SR31747 binding protein 1; SR-BP; SIG-1R; Opioid receptor, sigma 1, isoform 1; OPRS1 protein; Aging-associated gene 8 protein; AAG8
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| Representative Drug(s) | Iloperidone | Drug Info | IC50 = 64 nM | Click to Show More | [16] | |
| 2 | Abaperidone | Drug Info | Ki = 490 nM | [11] | ||
| Co-Target Name | Adrenergic receptor alpha-1B (ADRA1B) | Successful Target | ||||
| UniProt ID | ADA1B_HUMAN | |||||
| Gene Name | ADRA1B | |||||
| Synonyms |
Alpha-1B adrenoreceptor; Alpha-1B adrenoceptor; Alpha-1B adrenergic receptor; Alpha 1B-adrenoreceptor; Alpha 1B-adrenoceptor
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 100 nM | [17] | ||
| Co-Target Name | Adrenergic receptor alpha-1A (ADRA1A) | Successful Target | ||||
| UniProt ID | ADA1A_HUMAN | |||||
| Gene Name | ADRA1A | |||||
| Synonyms |
Alpha-adrenergic receptor 1c; Alpha-1C adrenergic receptor; Alpha-1A adrenoreceptor; Alpha-1A adrenoceptor; Alpha-1A adrenergic receptor; Alpha adrenergic receptor 1c; Alpha 1A-adrenoreceptor; Alpha 1A-adrenoceptor; ADRA1C
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 100 nM | [17] | ||
| Co-Target Name | Adrenergic receptor alpha-2A (ADRA2A) | Successful Target | ||||
| UniProt ID | ADA2A_HUMAN | |||||
| Gene Name | ADRA2A | |||||
| Synonyms |
Alpha-2AAR; Alpha-2A adrenoreceptor; Alpha-2A adrenoceptor; Alpha-2A adrenergic receptor; Alpha-2 adrenergic receptor subtype C10; ADRAR; ADRA2R
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 100 nM | [17] | ||
| Co-Target Name | Adrenergic receptor alpha-2C (ADRA2C) | Successful Target | ||||
| UniProt ID | ADA2C_HUMAN | |||||
| Gene Name | ADRA2C | |||||
| Synonyms |
Subtype C4; Alpha-2CAR; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; ADRA2RL2; ADRA2L2
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 100 nM | [17] | ||
| Co-Target Name | Adrenergic receptor Alpha-2 (ADRA2) | Successful Target | ||||
| UniProt ID | ADA2A_HUMAN; ADA2B_HUMAN; ADA2C_HUMAN | |||||
| Gene Name | NO-GeName | |||||
| Synonyms |
Alpha-2 adrenergic receptor; Alpha(2)-adrenoceptor
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| Representative Drug(s) | ZOTEPINE | Drug Info | Ki = 180 nM | Click to Show More | [5] | |
| 2 | ZOTEPINE | Drug Info | Ki = 180 nM | [5] | ||
| Co-Target Name | Norepinephrine transporter (NET) | Successful Target | ||||
| UniProt ID | SC6A2_HUMAN | |||||
| Gene Name | SLC6A2 | |||||
| Synonyms |
Solute carrier family 6 member 2; Sodium-dependent noradrenaline transporter; SLC6A2; NET1; NET; NAT1
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| Representative Drug(s) | METHYLENEDIOXYMETHAMPHETAMINE | Drug Info | Ki = 398 nM | [20] | ||
| Co-Target Name | 5-HT 3 receptor (5HT3R) | Successful Target | ||||
| UniProt ID | 5HT3A_HUMAN; 5HT3B_HUMAN; 5HT3C_HUMAN; 5HT3D_HUMAN; 5HT3E_HUMAN | |||||
| Gene Name | NO-GeName | |||||
| Synonyms |
5-hydroxytryptamine receptor type 3; 5-hydroxytryptamine receptor 3; 5-HT3R; 5-HT3 receptor; 5-HT-3
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 501.19 nM | [15] | ||
| Co-Target Name | Muscarinic acetylcholine receptor M4 (CHRM4) | Successful Target | ||||
| UniProt ID | ACM4_HUMAN | |||||
| Gene Name | CHRM4 | |||||
| Synonyms |
M4 receptor; CHRM4
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| Representative Drug(s) | ZOTEPINE | Drug Info | Ki = 550 nM | Click to Show More | [10] | |
| 2 | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | Voltage-gated potassium channel Kv11.1 (KCNH2) | Successful Target | ||||
| UniProt ID | KCNH2_HUMAN | |||||
| Gene Name | KCNH2 | |||||
| Synonyms |
hERG1; hERG-1; Voltage-gated potassium channel subunit Kv11.1; Potassium voltage-gated channel subfamily H member 2; HERG K+ channel; HERG; H-ERG; Ether-a-go-go-related protein 1; Ether-a-go-go-related gene potassium channel 1; Ether-a-go-go related protein 1; Ether-a-go-go related gene potassium channel 1; Eag related protein 1; Eag homolog; ERG-1; ERG
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 598 nM | [21] | ||
| Co-Target Name | Multidrug resistance protein 1 (ABCB1) | Clinical trial Target | ||||
| UniProt ID | MDR1_HUMAN | |||||
| Gene Name | ABCB1 | |||||
| Synonyms |
PGY1; P-glycoprotein 1; MDR1; CD243 antigen; CD243; ATP-binding cassette sub-family B member 1
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| Representative Drug(s) | Aripiprazole | Drug Info | IC50 = 780 nM | [23] | ||
| Co-Target Name | Dopamine transporter (DAT) | Successful Target | ||||
| UniProt ID | SC6A3_HUMAN | |||||
| Gene Name | SLC6A3 | |||||
| Synonyms |
Solute carrier family 6 member 3; Sodium-dependent dopamine transporter; DAT1; DAT; DA transporter
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| Representative Drug(s) | METHYLENEDIOXYMETHAMPHETAMINE | Drug Info | Ki = 897 nM | [20] | ||
| Co-Target Name | Adrenergic receptor alpha-2B (ADRA2B) | Successful Target | ||||
| UniProt ID | ADA2B_HUMAN | |||||
| Gene Name | ADRA2B | |||||
| Synonyms |
Subtype C2; Alpha-2BAR; Alpha-2B adrenoreceptor; Alpha-2B adrenoceptor; Alpha-2B adrenergic receptor; Alpha-2 adrenergic receptor subtype C2; ADRA2RL1; ADRA2L1
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 1000 nM | [17] | ||
| Co-Target Name | Muscarinic acetylcholine receptor M1 (CHRM1) | Successful Target | ||||
| UniProt ID | ACM1_HUMAN | |||||
| Gene Name | CHRM1 | |||||
| Synonyms |
M1 receptor
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | Muscarinic acetylcholine receptor M2 (CHRM2) | Successful Target | ||||
| UniProt ID | ACM2_HUMAN | |||||
| Gene Name | CHRM2 | |||||
| Synonyms |
M2 receptor; CHRM2
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | Muscarinic acetylcholine receptor M3 (CHRM3) | Successful Target | ||||
| UniProt ID | ACM3_HUMAN | |||||
| Gene Name | CHRM3 | |||||
| Synonyms |
M3 receptor; CHRM3
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | Muscarinic acetylcholine receptor M5 (CHRM5) | Successful Target | ||||
| UniProt ID | ACM5_HUMAN | |||||
| Gene Name | CHRM5 | |||||
| Synonyms |
CHRM5
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | Dopamine D5 receptor (D5R) | Successful Target | ||||
| UniProt ID | DRD5_HUMAN | |||||
| Gene Name | DRD5 | |||||
| Synonyms |
Dopamine receptor 5; DRD5; D1beta dopamine receptor; D(5)D(1B) dopamine receptor dopamine receptor; D(5) dopamine receptor
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | 5-HT 1E receptor (HTR1E) | Successful Target | ||||
| UniProt ID | 5HT1E_HUMAN | |||||
| Gene Name | HTR1E | |||||
| Synonyms |
Serotonin receptor 1E; S31; 5-hydroxytryptamine receptor 1E; 5-HT1E; 5-HT-1E; 5-HT 1E
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki ~ 1000 nM | [17] | ||
| Co-Target Name | 5-HT 3A receptor (HTR3A) | Successful Target | ||||
| UniProt ID | 5HT3A_HUMAN | |||||
| Gene Name | HTR3A | |||||
| Synonyms |
Serotonin-gated ion channel receptor; Serotonin receptor 3A; HTR3; 5HT3R; 5-hydroxytryptamine receptor 3A; 5-HT3RA; 5-HT3A; 5-HT3-A; 5-HT 3A
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 1000 nM | [17] | ||
| Co-Target Name | 5-HT 5A receptor (HTR5A) | Successful Target | ||||
| UniProt ID | 5HT5A_HUMAN | |||||
| Gene Name | HTR5A | |||||
| Synonyms |
Serotonin receptor 5A; 5-hydroxytryptamine receptor 5A; 5-HT5A; 5-HT-5A; 5-HT-5; 5-HT 5A
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| Representative Drug(s) | Aripiprazole | Drug Info | Ki = 1000 nM | [17] | ||
| Co-Target Name | 5-HT 7 receptor (HTR7) | Clinical trial Target | ||||
| UniProt ID | 5HT7R_HUMAN | |||||
| Gene Name | HTR7 | |||||
| Synonyms |
Serotonin receptor 7; 5HT7; 5-hydroxytryptamine receptor 7; 5-HT7 receptor; 5-HT7; 5-HT-X; 5-HT-7
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| Representative Drug(s) | Metergolin | Drug Info | Ki = 6.31 nM | Click to Show More | [25] | |
| 2 | Aripiprazole | Drug Info | Ki = 10.3 nM | [3] | ||
| 3 | TRYPTAMINE | Drug Info | Ki = 158.49 nM | [28] | ||
| Co-Target Name | 5-HT 6 receptor (HTR6) | Clinical trial Target | ||||
| UniProt ID | 5HT6R_HUMAN | |||||
| Gene Name | HTR6 | |||||
| Synonyms |
Serotonin receptor 6; 5-hydroxytryptamine receptor 6; 5-HT6 receptor; 5-HT6; 5-HT-6
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| Representative Drug(s) | TRYPTAMINE | Drug Info | Ki = 70 nM | Click to Show More | [26] | |
| 2 | Aripiprazole | Drug Info | Ki = 89 nM | [27] | ||
| Co-Target Name | Myeloperoxidase (MPO) | Clinical trial Target | ||||
| UniProt ID | PERM_HUMAN | |||||
| Gene Name | MPO | |||||
| Synonyms |
MPO
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| Representative Drug(s) | TRYPTAMINE | Drug Info | IC50 = 770 nM | [29] | ||
| Co-Target Name | HUAMN alpha-1 adrenergic receptor (ADRA1) | Literature-reported Target | ||||
| UniProt ID | ADA1A_HUMAN; ADA1B_HUMAN; ADA1D_HUMAN | |||||
| Gene Name | ADRA1A; ADRA1B; ADRA1D | |||||
| Synonyms |
Alpha-1 adrenoreceptor
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| Representative Drug(s) | ZOTEPINE | Drug Info | Ki = 3.4 nM | [10] | ||
| References | Top | ||||
|---|---|---|---|---|---|
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| REF 3 | Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands. Bioorg Med Chem. 2016 Aug 15;24(16):3464-71. | ||||
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| REF 8 | Synthesis and biological evaluation of new multi-target 3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives with potential antidepressant effect. Eur J Med Chem. 2019 Dec 1;183:111736. | ||||
| REF 9 | Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1834-8. | ||||
| REF 10 | Selective optimization of side activities: another way for drug discovery. J Med Chem. 2004 Mar 11;47(6):1303-14. | ||||
| REF 11 | 7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics. 2. Pharmacological profile of 7-[3-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-piperidin-1-yl]propoxy]-3-(hydroxymeth yl)chromen -4-one (abaperidone, FI-8602). J Med Chem. 1998 Dec 31;41(27):5402-9. | ||||
| REF 12 | 4-(Phenylsulfonyl)piperidines: novel, selective, and bioavailable 5-HT(2A) receptor antagonists. J Med Chem. 2002 Jan 17;45(2):492-503. | ||||
| REF 13 | Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies. J Med Chem. 2014 Nov 26;57(22):9578-97. | ||||
| REF 14 | Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors. J Med Chem. 1996 Jan 5;39(1):314-22. | ||||
| REF 15 | Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. J Med Chem. 2007 Oct 18;50(21):5103-8. | ||||
| REF 16 | 3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873). J Med Chem. 1995 Mar 31;38(7):1119-31. | ||||
| REF 17 | The synthesis and receptor binding affinities of DDD-016, a novel, potential, atypical antipsychotic. Medchemcomm. 2012;3:580-3. | ||||
| REF 18 | Synthesis and in vivo evaluation of phenethylpiperazine amides: selective 5-hydroxytryptamine(2A) receptor antagonists for the treatment of insomnia. J Med Chem. 2010 Aug 12;53(15):5696-706. | ||||
| REF 19 | Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. J Med Chem. 2017 Apr 13;60(7):2908-29. | ||||
| REF 20 | An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3411-5. | ||||
| REF 21 | 6-Alkoxyisoindolin-1-one based dopamine D2 partial agonists as potential antipsychotics. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5666-9. | ||||
| REF 22 | High-efficacy 5-HT1A agonists for antidepressant treatment: a renewed opportunity. J Med Chem. 2007 Oct 4;50(20):5024-33. | ||||
| REF 23 | A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields. J Med Chem. 2011 Mar 24;54(6):1740-51. | ||||
| REF 24 | Novel spirotetracyclic zwitterionic dual H(1)/5-HT(2A) receptor antagonists for the treatment of sleep disorders. J Med Chem. 2010 Nov 11;53(21):7778-95. | ||||
| REF 25 | Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives. J Med Chem. 2003 Dec 18;46(26):5638-50. | ||||
| REF 26 | 5-ZATRYPTAMINE ANALOGS AS h5-HT6 SEROTONIN RECEPTOR LIGANDS. Med Chem Res. 2005;4:1-18. | ||||
| REF 27 | Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects. Eur J Med Chem. 2018 Feb 10;145:790-804. | ||||
| REF 28 | Structure-activity relationships of serotonin 5-HT 7 receptors ligands: A review. Eur J Med Chem. 2019 Dec 1;183:111705. | ||||
| REF 29 | Design, synthesis, and structure-activity relationship studies of novel 3-alkylindole derivatives as selective and highly potent myeloperoxidase inhibitors. J Med Chem. 2013 May 23;56(10):3943-58. | ||||
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