Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03MVY
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| Former ID |
DNC004434
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| Drug Name |
2-(5-Thiophen-2-yl-1H-indol-3-yl)-ethylamine
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| Synonyms |
CHEMBL355517; 2-(5-Thiophen-2-yl-1H-indol-3-yl)-ethylamine; SCHEMBL8686120; BDBM50088863; AKOS022550938; 3-(2-Aminoethyl)-5-(2-thienyl)-1H-indole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H14N2S
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| Canonical SMILES |
C1=CSC(=C1)C2=CC3=C(C=C2)NC=C3CCN
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| InChI |
1S/C14H14N2S/c15-6-5-11-9-16-13-4-3-10(8-12(11)13)14-2-1-7-17-14/h1-4,7-9,16H,5-6,15H2
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| InChIKey |
KULFBKTWESBCBG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1B receptor (HTR1B) | Target Info | Inhibitor | [1] |
| 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 5-Thienyltryptamine derivatives as serotonin 5-HT1B/1D receptor agonists: potential treatments for migraine. Bioorg Med Chem Lett. 2000 May 1;10(9):903-5. | |||
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