Drug Information
Drug General Information | Top | |||
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Drug ID |
D03XAE
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Former ID |
DNC004555
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Drug Name |
[2-(5-Ethyl-1H-indol-3-yl)-ethyl]-dimethyl-amine
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Synonyms |
CHEMBL50492; 171783-25-8; 5-Ethyl-DMT; [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-dimethyl-amine; DTXSID30444736; BDBM50049099
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H20N2
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Canonical SMILES |
CCC1=CC2=C(C=C1)NC=C2CCN(C)C
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InChI |
1S/C14H20N2/c1-4-11-5-6-14-13(9-11)12(10-15-14)7-8-16(2)3/h5-6,9-10,15H,4,7-8H2,1-3H3
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InChIKey |
ZEHXYLDGQMEYAX-UHFFFAOYSA-N
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CAS Number |
CAS 171783-25-8
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 1B receptor (HTR1B) | Target Info | Inhibitor | [1] |
5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | 5-Alkyltryptamine derivatives as highly selective and potent 5-HT1D receptor agonists. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1707-9. |
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