Drug Information
Drug General Information | Top | |||
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Drug ID |
D04PBA
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Former ID |
DNC003530
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Drug Name |
3-(4-Benzyl-piperazin-1-yl)-phenol
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Synonyms |
CHEMBL88365; 3-(4-Benzyl-piperazin-1-yl)-phenol; SCHEMBL13902706; ZINC26638652; BDBM50069907
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C17H20N2O
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Canonical SMILES |
C1CN(CCN1CC2=CC=CC=C2)C3=CC(=CC=C3)O
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InChI |
1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2
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InChIKey |
BISVFNHMXVNVMG-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Dopamine D2 receptor (D2R) | Target Info | Inhibitor | [1] |
Dopamine D3 receptor (D3R) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Dopaminergic synapse | ||||
Rap1 signaling pathway | ||||
cAMP signaling pathway | ||||
Gap junction | ||||
Parkinson's disease | ||||
Cocaine addiction | ||||
Alcoholism | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Dopamine receptor mediated signaling pathway | ||||
Nicotine pharmacodynamics pathway | ||||
Reactome | Dopamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Nicotine Activity on Dopaminergic Neurons | ||||
GPCRs, Other | ||||
Hypothetical Network for Drug Addiction | ||||
Genes and (Common) Pathways Underlying Drug Addiction |
References | Top | |||
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REF 1 | New generation dopaminergic agents. 5. Heterocyclic bioisosteres that exploit the 3-OH-N1-phenylpiperazine dopaminergic template. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2675-80. |
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