Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06QKD
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| Former ID |
DNC012797
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| Drug Name |
4-(4-Isopropyl-morpholin-2-yl)-benzene-1,2-diol
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| Synonyms |
CHEMBL268881; NSC622468; 4-(4-Isopropyl-2-morpholinyl)-1,2-benzenediol hydrochloride; AC1L7GLH; AC1Q7ACF; 4-(4-Isopropyl-morpholin-2-yl)-benzene-1,2-diol; BDBM50000499; AKOS022660109; NCI60_006589; 4-(4-isopropylmorpholin-2-yl)benzene-1,2-diol; 4-(4-propan-2-ylmorpholin-2-yl)benzene-1,2-diol; 1,2-benzenediol, 4-[4-(1-methylethyl)-2-morpholinyl]-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H19NO3
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| Canonical SMILES |
CC(C)N1CCOC(C1)C2=CC(=C(C=C2)O)O
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| InChI |
1S/C13H19NO3/c1-9(2)14-5-6-17-13(8-14)10-3-4-11(15)12(16)7-10/h3-4,7,9,13,15-16H,5-6,8H2,1-2H3
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| InChIKey |
SUYJAACXNVNFGP-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Inhibitor | [1] |
| Adrenergic receptor alpha-1B (ADRA1B) | Target Info | Inhibitor | [1] | |
| Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| AMPK signaling pathway | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Vascular smooth muscle contraction | ||||
| Salivary secretion | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Pathway Interaction Database | LPA receptor mediated events | |||
| Reactome | Adrenoceptors | |||
| G alpha (q) signalling events | ||||
| G alpha (12/13) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Endothelin Pathways | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| AMPK Signaling | ||||
| GPCRs, Other | ||||
| Vitamin D Receptor Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic rece... J Med Chem. 1992 Mar 20;35(6):1009-18. | |||
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