Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08KDP
|
|||
| Former ID |
DNC000257
|
|||
| Drug Name |
AS-8112
|
|||
| Indication | Vomiting [ICD-11: MD90; ICD-10: R11; ICD-9: 787] | Terminated | [1] | |
| Company |
Dainippon
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 3A receptor (HTR3A) | Target Info | Antagonist | [2] |
| Dopamine D3 receptor (D3R) | Target Info | Antagonist | [2] | |
| KEGG Pathway | Serotonergic synapse | |||
| Neuroactive ligand-receptor interaction | ||||
| Dopaminergic synapse | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | 5HT3 type receptor mediated signaling pathway | |||
| Reactome | Ligand-gated ion channel transport | |||
| Dopamine receptors | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Iron uptake and transport | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| Nicotine Activity on Dopaminergic Neurons | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009088) | |||
| REF 2 | Emerging drugs for chemotherapy-induced emesis. Expert Opin Emerg Drugs. 2006 Mar;11(1):137-51. | |||
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