Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08OJU
|
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| Former ID |
DIB009432
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| Drug Name |
SOU-001
|
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| Synonyms |
AA-10020; DRP-001
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|
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| Indication | Urinary incontinence [ICD-11: MF50.2; ICD-9: 788.3] | Discontinued in Phase 2 | [1] | |
| Company |
Arachnova Therapeutics Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Modulator | [2] |
| Adrenergic receptor alpha-1B (ADRA1B) | Target Info | Modulator | [2] | |
| Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Modulator | [2] | |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Vascular smooth muscle contraction | ||||
| Salivary secretion | ||||
| AMPK signaling pathway | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Pathway Interaction Database | LPA receptor mediated events | |||
| Reactome | Adrenoceptors | |||
| G alpha (q) signalling events | ||||
| G alpha (12/13) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Vitamin D Receptor Pathway | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| AMPK Signaling | ||||
| Endothelin Pathways | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014478) | |||
| REF 2 | Drug repositioning: identifying and developing new uses for existing drugs. Nat Rev Drug Discov. 2004 Aug;3(8):673-83. | |||
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