Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D09NXU
|
|||
Former ID |
DNC012644
|
|||
Drug Name |
4-(2,3-Dihydro-1H-phenalen-1-yl)-1H-imidazole
|
|||
Synonyms |
CHEMBL105328; 178556-61-1; CTK0A6889; DTXSID50441101; 4-[(2,3-Dihydro-1H-phenalen)-1-yl]-1H-imidazole; 1H-Imidazole, 4-(2,3-dihydro-1H-phenalen-1-yl)-
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C16H14N2
|
|||
Canonical SMILES |
C1CC2=CC=CC3=C2C(=CC=C3)C1C4=CN=CN4
|
|||
InChI |
1S/C16H14N2/c1-3-11-5-2-6-14-13(15-9-17-10-18-15)8-7-12(4-1)16(11)14/h1-6,9-10,13H,7-8H2,(H,17,18)
|
|||
InChIKey |
KFGFWNKBPWPCKX-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 178556-61-1
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Inhibitor | [1] |
Adrenergic receptor alpha-1B (ADRA1B) | Target Info | Inhibitor | [1] | |
Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
cGMP-PKG signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Adrenergic signaling in cardiomyocytes | ||||
Vascular smooth muscle contraction | ||||
Salivary secretion | ||||
AMPK signaling pathway | ||||
NetPath Pathway | IL2 Signaling Pathway | |||
Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
Pathway Interaction Database | LPA receptor mediated events | |||
Reactome | Adrenoceptors | |||
G alpha (q) signalling events | ||||
G alpha (12/13) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
Calcium Regulation in the Cardiac Cell | ||||
GPCRs, Class A Rhodopsin-like | ||||
Vitamin D Receptor Pathway | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
AMPK Signaling | ||||
GPCRs, Other | ||||
Endothelin Pathways |
References | Top | |||
---|---|---|---|---|
REF 1 | Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene deriva... J Med Chem. 1996 Jul 19;39(15):3001-13. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.