Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0BC6Q
|
|||
Former ID |
DNC003842
|
|||
Drug Name |
AGN-193080
|
|||
Synonyms |
AGN-193080; CHEMBL298936; SCHEMBL8348700; BDBM50052882; L012655
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Structure |
Download2D MOL |
|||
Formula |
C12H16N4O
|
|||
Canonical SMILES |
CC1=C(C=CC2=C1NCCO2)NC3=NCCN3
|
|||
InChI |
1S/C12H16N4O/c1-8-9(16-12-14-4-5-15-12)2-3-10-11(8)13-6-7-17-10/h2-3,13H,4-7H2,1H3,(H2,14,15,16)
|
|||
InChIKey |
OSJZLDGTMVBIRV-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Inhibitor | [1] |
Adrenergic receptor alpha-1B (ADRA1B) | Target Info | Inhibitor | [1] | |
Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
cGMP-PKG signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Adrenergic signaling in cardiomyocytes | ||||
Vascular smooth muscle contraction | ||||
Salivary secretion | ||||
AMPK signaling pathway | ||||
NetPath Pathway | IL2 Signaling Pathway | |||
Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
Pathway Interaction Database | LPA receptor mediated events | |||
Reactome | Adrenoceptors | |||
G alpha (q) signalling events | ||||
G alpha (12/13) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
Calcium Regulation in the Cardiac Cell | ||||
GPCRs, Class A Rhodopsin-like | ||||
Vitamin D Receptor Pathway | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
AMPK Signaling | ||||
GPCRs, Other | ||||
Endothelin Pathways |
References | Top | |||
---|---|---|---|---|
REF 1 | Analogs of UK 14,304: Structural features responsible for alpha2 adrenoceptor activity, Bioorg. Med. Chem. Lett. 5(15):1745-1750 (1995). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.