Drug Information
Drug General Information | Top | |||
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Drug ID |
D0D3PZ
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Former ID |
DIB019758
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Drug Name |
dipropyl-5-CT
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Synonyms |
DP-5-CT; DP5CT; N,N-dipropylcarboxamidotryptamine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C17H25N3O
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Canonical SMILES |
CCCN(CCC)CCC1=CNC2=C1C=C(C=C2)C(=O)N
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InChI |
1S/C17H25N3O/c1-3-8-20(9-4-2)10-7-14-12-19-16-6-5-13(17(18)21)11-15(14)16/h5-6,11-12,19H,3-4,7-10H2,1-2H3,(H2,18,21)
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InChIKey |
DPXOFRGRKPFZOD-UHFFFAOYSA-N
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CAS Number |
CAS 74885-25-9
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PubChem Compound ID | ||||
PubChem Substance ID |
10252872, 11111033, 15467773, 26755673, 46232141, 47350433, 47425374, 47574448, 47574449, 47796120, 48020066, 48095614, 50111034, 51017598, 57348262, 85209642, 85787317, 90340592, 104443505, 124749691, 124879818, 124879819, 127770003, 131342363, 134223554, 135112296, 135650195, 179235777, 234353577, 242145455
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ChEBI ID |
CHEBI:92566
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Target and Pathway | Top | |||
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Target(s) | 5-HT 1B receptor (HTR1B) | Target Info | Agonist | [2] |
5-HT 1D receptor (HTR1D) | Target Info | Agonist | [2] | |
5-HT 1F receptor (HTR1F) | Target Info | Agonist | [3] | |
5-HT 7 receptor (HTR7) | Target Info | Agonist | [4] | |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Ras signaling pathway | ||||
Calcium signaling pathway | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | |||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
G alpha (s) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other | ||||
Serotonin Receptor 4/6/7 and NR3C Signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 122). | |||
REF 2 | Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3630-4. | |||
REF 3 | Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):408-12. | |||
REF 4 | Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b). Br J Pharmacol. 1997 Sep;122(1):126-32. |
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