Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0L5VS
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| Former ID |
DNC004457
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| Drug Name |
KF-17837
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| Synonyms |
CHEMBL27508; (E)-8-(3,4-Dimethoxystyryl)-7-methyl-1,3-dipropylxanthine; 141807-96-7; 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(3,4-dimethoxyphenyl)ethenyl)-1,3-dipropyl-7-methyl-, (E)-; UQGGPCQNHJCOPS-PKNBQFBNSA-N; 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-7-methyl-1,3-dipropylpurine-2,6-dione; AC1O68AZ; SCHEMBL537086; SCHEMBL537085; SCHEMBL9364001; 8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione; BDBM50006710; KF-17387; LS-126824; L006852
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| Drug Type |
Small molecular drug
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| Indication | Parkinson disease [ICD-11: 8A00.0; ICD-9: 332] | Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H28N4O4
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| Canonical SMILES |
CCCN1C2=C(C(=O)N(C1=O)CCC)N(C(=N2)C=CC3=CC(=C(C=C3)OC)OC)C
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| InChI |
1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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| InChIKey |
UQGGPCQNHJCOPS-PKNBQFBNSA-N
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| CAS Number |
CAS 141807-96-7
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005980) | |||
| REF 2 | 2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic gluc... J Med Chem. 2001 Jan 18;44(2):170-9. | |||
| REF 3 | Photoisomerization of a potent and selective adenosine A2 antagonist, (E)-1,3-Dipropyl-8-(3,4-dimethoxystyryl)-7-methylxanthine. J Med Chem. 1993 Nov 12;36(23):3731-3. | |||
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