Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0PN8D
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| Former ID |
DNC004503
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| Drug Name |
1-(7-Methoxy-naphthalen-2-yl)-piperazine
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| Synonyms |
1-(7-methoxynaphthalen-2-yl)piperazine; CHEMBL129661; 1174207-86-3; 1-(7-Methoxy-naphthalen-2-yl)-piperazine; ZINC27313663; BDBM50061300; DA-15050
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H18N2O
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| Canonical SMILES |
COC1=CC2=C(C=CC(=C2)N3CCNCC3)C=C1
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| InChI |
1S/C15H18N2O/c1-18-15-5-3-12-2-4-14(10-13(12)11-15)17-8-6-16-7-9-17/h2-5,10-11,16H,6-9H2,1H3
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| InChIKey |
FRTFBUOBLXTGSL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Inhibitor | [1] |
| 5-HT 1B receptor (HTR1B) | Target Info | Inhibitor | [1] | |
| 5-HT 1D receptor (HTR1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| 5HT1 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 5-HT1B receptor antagonist properties of novel arylpiperazide derivatives of 1-naphthylpiperazine. J Med Chem. 1997 Nov 21;40(24):3974-8. | |||
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