Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QH7H
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| Former ID |
DIB015420
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| Drug Name |
AMP-579
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| Synonyms |
RPR-100579; (1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Hyperlipidaemia [ICD-11: 5C80; ICD-10: E78.5] | Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H28ClN5O3S
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| Canonical SMILES |
CCC(CC1=C(C=CS1)Cl)NC2=C3C=CN(C3=NC=N2)C4CC(C(C4O)O)C(=O)NCC
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| InChI |
1S/C22H28ClN5O3S/c1-3-12(9-17-15(23)6-8-32-17)27-20-13-5-7-28(21(13)26-11-25-20)16-10-14(18(29)19(16)30)22(31)24-4-2/h5-8,11-12,14,16,18-19,29-30H,3-4,9-10H2,1-2H3,(H,24,31)(H,25,26,27)/t12-,14+,16-,18-,19+/m1/s1
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| InChIKey |
CKQOOYMMAAPDKH-QODLLSGVSA-N
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| CAS Number |
CAS 213453-89-5
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Recent developments in adenosine receptor ligands and their potential as novel drugs. Biochim Biophys Acta. 2011 May; 1808(5): 1290-1308. | |||
| REF 2 | Adenosine A1/A2a receptor agonist AMP-579 induces acute and delayed preconditioning against in vivo myocardial stunning. Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2746-53. | |||
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