Drug Information
Drug General Information | Top | |||
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Drug ID |
D0RX6I
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Former ID |
DNC012636
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Drug Name |
4-((E)-1-Naphthalen-1-yl-propenyl)-1H-imidazole
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Synonyms |
CHEMBL102669; ZINC13757203
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H14N2
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Canonical SMILES |
CC=C(C1=CC=CC2=CC=CC=C21)C3=CN=CN3
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InChI |
1S/C16H14N2/c1-2-13(16-10-17-11-18-16)15-9-5-7-12-6-3-4-8-14(12)15/h2-11H,1H3,(H,17,18)/b13-2+
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InChIKey |
VDVBKYMIYSQNPM-XNJYKOPJSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Inhibitor | [1] |
Adrenergic receptor alpha-1B (ADRA1B) | Target Info | Inhibitor | [1] | |
Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Calcium signaling pathway | |||
cGMP-PKG signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
AMPK signaling pathway | ||||
Adrenergic signaling in cardiomyocytes | ||||
Vascular smooth muscle contraction | ||||
Salivary secretion | ||||
NetPath Pathway | IL2 Signaling Pathway | |||
Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
Pathway Interaction Database | LPA receptor mediated events | |||
Reactome | Adrenoceptors | |||
G alpha (q) signalling events | ||||
G alpha (12/13) signalling events | ||||
WikiPathways | Monoamine GPCRs | |||
Calcium Regulation in the Cardiac Cell | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
Endothelin Pathways | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
AMPK Signaling | ||||
GPCRs, Other | ||||
Vitamin D Receptor Pathway |
References | Top | |||
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REF 1 | Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene deriva... J Med Chem. 1996 Jul 19;39(15):3001-13. |
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