Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0T5KJ
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| Former ID |
DNC012803
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| Drug Name |
4-(3-Hydroxy-piperidin-3-yl)-benzene-1,2-diol
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| Synonyms |
CHEMBL7278; 100112-61-6; 1,2-benzenediol,4-(3-hydroxy-3-piperidinyl)-; 4-(3-Hydroxy-piperidin-3-yl)-benzene-1,2-diol; 1,2-Benzenediol, 4-(3-hydroxy-3-piperidinyl)-; CTK8G4032; BDBM50000496; AKOS022649735; 3-(3,4-Dihydroxyphenyl)piperidin-3-ol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H15NO3
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| Canonical SMILES |
C1CC(CNC1)(C2=CC(=C(C=C2)O)O)O
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| InChI |
1S/C11H15NO3/c13-9-3-2-8(6-10(9)14)11(15)4-1-5-12-7-11/h2-3,6,12-15H,1,4-5,7H2
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| InChIKey |
REBGJGKBMBFBHE-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor alpha-1A (ADRA1A) | Target Info | Inhibitor | [1] |
| Adrenergic receptor alpha-1B (ADRA1B) | Target Info | Inhibitor | [1] | |
| Adrenergic receptor alpha-1D (ADRA1D) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| cGMP-PKG signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Vascular smooth muscle contraction | ||||
| Salivary secretion | ||||
| AMPK signaling pathway | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Alpha adrenergic receptor signaling pathway | |||
| Pathway Interaction Database | LPA receptor mediated events | |||
| Reactome | Adrenoceptors | |||
| G alpha (q) signalling events | ||||
| G alpha (12/13) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| Vitamin D Receptor Pathway | ||||
| AMPK Signaling | ||||
| Endothelin Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic rece... J Med Chem. 1992 Mar 20;35(6):1009-18. | |||
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