Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V6DJ
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| Former ID |
DIB018659
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| Drug Name |
5-methylurapidil
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| Synonyms |
5 methylurapidil; 5-methyl-urapidil
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C21H31N5O3
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| Canonical SMILES |
CC1=C(N(C(=O)N(C1=O)C)C)NCCCN2CCN(CC2)C3=CC=CC=C3OC
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| InChI |
1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3
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| InChIKey |
HIHZDNKKIUQQSC-UHFFFAOYSA-N
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| CAS Number |
CAS 34661-85-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5416505, 7978603, 8153469, 11111937, 14854814, 17405829, 26753682, 29224677, 46500368, 47440498, 47959989, 48334744, 50064709, 50107230, 50107231, 53778381, 57322879, 78567119, 85208927, 85231281, 90340943, 92098503, 92303222, 103146517, 103299542, 103941453, 104309821, 117588404, 121362076, 124750374, 124800049, 124881772, 124881773, 128064993, 135072905, 135649841, 162841096, 163565229, 178126959, 179150352, 198946634, 232104651
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 489). | |||
| REF 2 | Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes. Jpn J Pharmacol. 2001 Jun;86(2):189-95. | |||
| REF 3 | Phe-308 and Phe-312 in transmembrane domain 7 are major sites of alpha 1-adrenergic receptor antagonist binding. Imidazoline agonists bind like ant... J Biol Chem. 2001 Jul 6;276(27):25366-71. | |||
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