miRNA General Information
miRNA Mature ID hsa-miR-574-3p
miRNA Stemloop AC MI0003581
miRNA Stemloop ID hsa-mir-574
Sequence cacgcucaugcacacacccaca
TTD Target(s) Regulated by This miRNA Epidermal growth factor receptor (EGFR) Successful Target Target Info [1]
Retinoic acid receptor RXR-alpha (RXRA) Successful Target Target Info [2]
Transforming growth factor beta 1 (TGFB1) Successful Target Target Info [3]
Ras-related C3 botulinum toxin substrate 1 (RAC1) Literature-reported Target Target Info [1]
Histone acetyltransferase p300 (EP300) Clinical trial Target Target Info [1]
Protein(s) Regulated by This miRNA Clathrin heavy chain 1 Regulated Protein [4]
Cullin-2 Regulated Protein [5]
Mothers against decapentaplegic homolog 4 Regulated Protein [6]
References
REF 1 Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer. PLoS One. 2013;8(3):e58929.
REF 2 Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells. PLoS One. 2013 Apr 23;8(4):e62582.
REF 3 Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-1. Gene. 2017 Mar 20;605:63-69.
REF 4 MicroRNA-574-3p, identified by microRNA library-based functional screening, modulates tamoxifen response in breast cancer.Sci Rep. 2015 Jan 6;5:7641.
REF 5 Aberrant expression of microRNAs in gastric cancer and biological significance of miR-574-3p.Int Immunopharmacol. 2012 Aug;13(4):468-75.
REF 6 miR-574-3p acts as a tumor promoter in osteosarcoma by targeting SMAD4 signaling pathway.Oncol Lett. 2016 Dec;12(6):5247-5253.

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