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Protein General Information |
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Full Name |
E3 ubiquitin-protein ligase AMFR (AMFR)
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UniProt ID |
AMFR_HUMAN
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Gene Name |
AMFR
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Gene ID |
267
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
cAMP-dependent chloride channel (CFTR) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Valosin-containing protein p97 (VCP) |
Target Info
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PPI Info
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[2] |
Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Nature. 2015 Dec 24;528(7583):510-6.
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REF 2 |
VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. PLoS One. 2013;8(1):e55724.
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REF 3 |
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. Cell Rep. 2012 Dec 27;2(6):1633-44.
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