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| Protein General Information |
Top |
| Full Name |
F-box only protein 4 (FBXO4)
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| UniProt ID |
FBX4_HUMAN
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| Gene Name |
FBXO4
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| Gene ID |
26272
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| Interacting TTD Target Information |
Top |
| Interacting Clinical trial Target(s) |
G1/S-specific cyclin-D1 (CCND1) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Telomeric repeat-binding factor 1 (TERF1) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex. Mol Cell. 2006 Nov 3;24(3):355-66.
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| REF 2 |
The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance. J Biol Chem. 2006 Jan 13;281(2):759-68.
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