| References |
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| REF 1 |
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism. J Biol Chem. 2005 Aug 19;280(33):29728-42.
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| REF 2 |
Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD. J Biol Chem. 2002 Mar 15;277(11):8847-53.
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| REF 3 |
Cyclin D1 associates with the TBP-associated factor TAF(II)250 to regulate Sp1-mediated transcription. Oncogene. 1999 Jan 7;18(1):239-47.
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| REF 4 |
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity. Oncogene. 2000 Nov 23;19(50):5703-11.
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| REF 5 |
A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene. 2005 Jan 13;24(3):431-44.
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Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells. Mol Cancer Ther. 2010 Jun;9(6):1596-608.
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| REF 7 |
Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors. J Biol Chem. 2002 Aug 9;277(32):28733-41.
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| REF 8 |
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J Biol Chem. 2005 Apr 29;280(17):16934-41.
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| REF 9 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
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| REF 10 |
CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms. Mol Cell Biol. 2007 Jun;27(12):4273-82.
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| REF 11 |
Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis. Mol Cell Biol. 2004 Nov;24(21):9527-41.
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| REF 12 |
Biologic and biochemical analyses of p16(INK4a) mutations from primary tumors. J Natl Cancer Inst. 1999 Sep 15;91(18):1569-74.
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| REF 13 |
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage. J Biol Chem. 1996 May 31;271(22):13283-91.
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| REF 14 |
Cyclin-dependent kinase-2 (Cdk2) forms an inactive complex with cyclin D1 since Cdk2 associated with cyclin D1 is not phosphorylated by Cdk7-cyclin-H. Eur J Biochem. 1996 Apr 15;237(2):460-7.
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| REF 15 |
Cyclin D2 activates Cdk2 in preference to Cdk4 in human breast epithelial cells. Oncogene. 1997 Mar 20;14(11):1329-40.
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| REF 16 |
p21WAF1/CIP1 mutants deficient in inhibiting cyclin-dependent kinases (CDKs) can promote assembly of active cyclin D/CDK4(6) complexes in human tumor cells. Cancer Res. 1998 Nov 15;58(22):5053-6.
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| REF 17 |
Inducible expression of cyclin D1 in T-47D human breast cancer cells is sufficient for Cdk2 activation and pRB hyperphosphorylation. J Cell Biochem. 1996 Mar 1;60(3):363-78.
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| REF 18 |
Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. Mol Biol Cell. 1997 Feb;8(2):287-301.
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| REF 19 |
The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2. EMBO J. 1996 Dec 16;15(24):7060-9.
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| REF 20 |
Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73. J Biol Chem. 2003 Jul 25;278(30):27421-31.
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| REF 21 |
Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases. J Biol Chem. 1997 May 9;272(19):12738-46.
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| REF 22 |
Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein. Biochem Biophys Res Commun. 1999 Sep 16;263(1):35-40.
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| REF 23 |
Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein. Oncogene. 2001 Sep 27;20(43):6152-63.
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| REF 24 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 25 |
Identification of human protein interaction domains using an ORFeome-based yeast two-hybrid fragment library. J Proteome Res. 2013 Jul 5;12(7):3181-92.
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| REF 26 |
Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. Nat Commun. 2017 Nov 16;8(1):1534.
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| REF 27 |
Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1). Genes Dev. 1999 Nov 15;13(22):3027-33.
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| REF 28 |
Calmodulin is essential for cyclin-dependent kinase 4 (Cdk4) activity and nuclear accumulation of cyclin D1-Cdk4 during G1. J Biol Chem. 1998 Dec 11;273(50):33279-86.
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| REF 29 |
BCR-ABL1-induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia. Br J Haematol. 2008 Aug;142(4):571-82.
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| REF 30 |
A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation. PLoS One. 2006 Dec 27;1:e128.
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| REF 31 |
Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc. EMBO J. 1996 Dec 2;15(23):6595-604.
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| REF 32 |
VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells. Cancer Res. 2002 Jun 1;62(11):3014-9.
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| REF 33 |
Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation. Oncogene. 2009 Dec 10;28(49):4317-25.
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| REF 34 |
Nucleolar GTP-binding Protein-1 (NGP-1) Promotes G1 to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21 Cip1/Waf1. J Biol Chem. 2015 Aug 28;290(35):21536-52.
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| REF 35 |
Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma. J Biol Chem. 2012 Nov 9;287(46):38523-30.
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| REF 36 |
Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells. J Neurosci. 2001 Feb 15;21(4):1274-82.
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| REF 37 |
Schizophrenia susceptibility gene product dysbindin-1 regulates the homeostasis of cyclin D1. Biochim Biophys Acta. 2016 Aug;1862(8):1383-91.
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| REF 38 |
The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding. J Biol Chem. 2003 Mar 14;278(11):9754-60.
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| REF 39 |
Self-assembling protein microarrays. Science. 2004 Jul 2;305(5680):86-90.
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| REF 40 |
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol Biol Cell. 1993 Sep;4(9):897-906.
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| REF 41 |
Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity. Cancer Res. 2005 Aug 1;65(15):6557-67.
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| REF 42 |
CDK-independent activation of estrogen receptor by cyclin D1. Cell. 1997 Feb 7;88(3):405-15.
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| REF 43 |
D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability. Cancer Res. 1999 May 15;59(10):2297-301.
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| REF 44 |
Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly. Circ Res. 2007 Jul 20;101(2):146-55.
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| REF 45 |
Retinoic acid inhibits the proliferative response induced by CD40 activation and interleukin-4 in mantle cell lymphoma. Cancer Res. 2005 Jan 15;65(2):587-95.
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| REF 46 |
Analysis of wild-type and mutant p21WAF-1 gene activities. Mol Cell Biol. 1996 Apr;16(4):1786-93.
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| REF 47 |
Cyclin-binding motifs are essential for the function of p21CIP1. Mol Cell Biol. 1996 Sep;16(9):4673-82.
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| REF 48 |
A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
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| REF 49 |
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
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| REF 50 |
Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. Cell. 2007 Jan 26;128(2):269-80.
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| REF 51 |
Regulated expression of cofilin and the consequent regulation of p27(kip1) are essential for G(1) phase progression. Cell Cycle. 2009 Aug;8(15):2365-74.
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| REF 52 |
C-terminal phosphorylation controls the stability and function of p27kip1. EMBO J. 2006 Nov 1;25(21):5159-70.
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| REF 53 |
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex. Mol Cell. 2006 Nov 3;24(3):355-66.
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| REF 54 |
The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma. Mol Cell Biol. 2013 Nov;33(22):4422-33.
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| REF 55 |
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 1993 Aug;7(8):1572-83.
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| REF 56 |
D-type cyclin-binding regions of proliferating cell nuclear antigen. J Biol Chem. 1994 Apr 15;269(15):11030-6.
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| REF 57 |
Dimerization of the amino terminal domain of p57Kip2 inhibits cyclin D1-cdk4 kinase activity. Oncogene. 2000 Feb 24;19(9):1147-52.
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| REF 58 |
Stabilization of MyoD by direct binding to p57(Kip2). J Biol Chem. 2000 Jun 23;275(25):18767-76.
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