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| Protein General Information (TTD Target) |
Top |
| Full Name |
CDK inhibitor 1C p57Kip2 (CDKN1C)
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Literature-reported
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Target Info
|
| UniProt ID |
CDN1C_HUMAN
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| Gene Name |
CDKN1C
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| Gene ID |
1028
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| References |
Top |
| REF 1 |
Dimerization of the amino terminal domain of p57Kip2 inhibits cyclin D1-cdk4 kinase activity. Oncogene. 2000 Feb 24;19(9):1147-52.
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| REF 2 |
The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domain. J Biol Chem. 2003 Nov 7;278(45):44255-64.
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| REF 3 |
Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10231-6.
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