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| Protein General Information (TTD Target) |
Top |
| Full Name |
Galectin-1 (LGALS1)
|
Patented-recorded
|
Target Info
|
| UniProt ID |
LEG1_HUMAN
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| Gene Name |
LGALS1
|
| Gene ID |
3956
|
| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
GTPase HRas (HRAS) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Knockdown of GnT-Va expression inhibits ligand-induced downregulation of the epidermal growth factor receptor and intracellular signaling by inhibiting receptor endocytosis. Glycobiology. 2009 May;19(5):547-59.
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| REF 2 |
Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation. Oncogene. 2001 Nov 8;20(51):7486-93.
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