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Protein General Information (TTD Target) |
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Full Name |
Ubiquitin thioesterase OTU1 (YOD1)
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Literature-reported
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Target Info
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UniProt ID |
OTU1_HUMAN
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Gene Name |
YOD1
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
Valosin-containing protein p97 (VCP) |
Target Info
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PPI Info
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[1] |
Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER. Mol Cell. 2009 Oct 9;36(1):28-38.
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REF 2 |
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell. 2013 Jul 3;154(1):169-84.
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