Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Phosphoinositide dependent protein kinase-1 (PDPK1) | Clinical trial | Target Info | ||
| UniProt ID | PDPK1_HUMAN | ||||
| Gene Name | PDPK1 | ||||
| Gene ID | 5170 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | RAC-alpha serine/threonine-protein kinase (AKT1) | Target Info | PPI Info | [1] | |
| Interacting Clinical trial Target(s) | Serine/threonine-protein kinase Sgk1 (SGK1) | Target Info | PPI Info | [2] | |
| Interacting Patented-recorded Target(s) | Ribosomal protein S6 kinase alpha-3 (RSK3) | Target Info | PPI Info | [3] | |
| Protein kinase C zeta (PRKCZ) | Target Info | PPI Info | [4] | ||
| Interacting Literature-reported Target(s) | Protein kinase N2 (PKN2) | Target Info | PPI Info | [5] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI. J Biol Chem. 2002 Apr 12;277(15):12874-8. | ||||
| REF 2 | NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function. J Biol Chem. 2007 Nov 30;282(48):35293-307. | ||||
| REF 3 | A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1. EMBO J. 2000 Jun 15;19(12):2924-34. | ||||
| REF 4 | Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science. 1998 Sep 25;281(5385):2042-5. | ||||
| REF 5 | Regulation of both PDK1 and the phosphorylation of PKC-zeta and -delta by a C-terminal PRK2 fragment. Biochemistry. 2002 Jan 15;41(2):561-9. | ||||
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