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| Protein General Information |
Top |
| Full Name |
DNA polymerase eta (POLH)
|
| UniProt ID |
POLH_HUMAN
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| Gene Name |
POLH
|
| Gene ID |
5429
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Proliferating cell nuclear antigen (PCNA) |
Target Info
|
PPI Info
|
[1] |
| Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell. 2004 May 21;14(4):491-500.
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| REF 2 |
Aberrant C-terminal domain of polymerase targets the functional enzyme to the proteosomal degradation pathway. DNA Repair (Amst). 2015 May;29:154-65.
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