| References |
Top |
| REF 1 |
A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. J Biol Chem. 2002 Oct 25;277(43):40362-7.
|
| REF 2 |
Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells. Nucleic Acids Res. 2001 Mar 15;29(6):1341-51.
|
| REF 3 |
The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance. J Biol Chem. 2014 May 9;289(19):13627-37.
|
| REF 4 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
|
| REF 5 |
Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. J Biol Chem. 2010 Apr 2;285(14):10362-9.
|
| REF 6 |
Characterisation of the interaction between WRN, the helicase/exonuclease defective in progeroid Werner's syndrome, and an essential replication factor, PCNA. Mech Ageing Dev. 2003 Feb;124(2):167-74.
|
| REF 7 |
WRN interacts physically and functionally with the recombination mediator protein RAD52. J Biol Chem. 2003 Sep 19;278(38):36476-86.
|
| REF 8 |
Characterization of the human and mouse WRN 3'-->5' exonuclease. Nucleic Acids Res. 2000 Jun 15;28(12):2396-405.
|
| REF 9 |
Proliferating cell nuclear antigen interacts with the CRL4 ubiquitin ligase subunit CDT2 in DNA synthesis-induced degradation of CDT1. J Biol Chem. 2018 Dec 7;293(49):18879-18889.
|
| REF 10 |
SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination. J Cell Biol. 2014 Jun 23;205(6):811-27.
|
| REF 11 |
The DNA-binding subunit p140 of replication factor C is upregulated in cycling cells and associates with G1 phase cell cycle regulatory proteins. J Mol Med (Berl). 1999 Apr;77(4):386-92.
|
| REF 12 |
Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block. Oncogene. 2002 Oct 31;21(50):7710-9.
|
| REF 13 |
A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.
|
| REF 14 |
DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories. EMBO J. 1998 Jul 1;17(13):3786-95.
|
| REF 15 |
A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammal... EMBO J. 1996 Aug 15;15(16):4423-33.
|
| REF 16 |
A complex consisting of human replication factor C p40, p37, and p36 subunits is a DNA-dependent ATPase and an intermediate in the assembly of the holoenzyme. J Biol Chem. 1997 Jul 25;272(30):18974-81.
|
| REF 17 |
The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):6-10.
|
| REF 18 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
|
| REF 19 |
A non-catalytic role of DNA polymerase in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks. Nucleic Acids Res. 2013 Mar 1;41(5):3079-93.
|
| REF 20 |
Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage. J Biol Chem. 2017 Nov 3;292(44):18227-18239.
|
| REF 21 |
Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis. Nature. 2001 Mar 15;410(6826):387-91.
|
| REF 22 |
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res. 2014 Jul;42(13):8433-48.
|
| REF 23 |
L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage. Cell Cycle. 2006 Aug;5(15):1675-80.
|
| REF 24 |
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) triggers MSH2 and Cdt2 protein-dependent degradation of the cell cycle and mismatch repair (MMR) inhibitor protein p21Waf1/Cip1. J Biol Chem. 2011 Aug 26;286(34):29531-9.
|
| REF 25 |
14-3-3 proteins play a role in the cell cycle by shielding cdt2 from ubiquitin-mediated degradation. Mol Cell Biol. 2014 Nov;34(21):4049-61.
|
| REF 26 |
Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4Cdt2 for PCNA and its ubiquitination activity in S phase. Genes Cells. 2018 Mar;23(3):200-213.
|
| REF 27 |
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 1993 Aug;7(8):1572-83.
|
| REF 28 |
D-type cyclin-binding regions of proliferating cell nuclear antigen. J Biol Chem. 1994 Apr 15;269(15):11030-6.
|
| REF 29 |
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res. 2012 Jul 1;72(13):3217-27.
|
| REF 30 |
Tyrosine phosphorylation controls PCNA function through protein stability. Nat Cell Biol. 2006 Dec;8(12):1359-68.
|
| REF 31 |
Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation. Cell Cycle. 2012 Jun 1;11(11):2128-36.
|
| REF 32 |
Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1. Structure. 2004 Dec;12(12):2209-19.
|
| REF 33 |
Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation. Oncogene. 2003 Jul 10;22(28):4301-13.
|
| REF 34 |
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen. EMBO J. 1998 Apr 15;17(8):2412-25.
|
| REF 35 |
The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21. J Biol Chem. 1997 Sep 26;272(39):24522-9.
|
| REF 36 |
p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11597-602.
|
| REF 37 |
Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA. Nucleic Acids Res. 1996 Jun 1;24(11):2036-43.
|
| REF 38 |
p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues. Oncogene. 2001 Jan 25;20(4):484-9.
|
| REF 39 |
Cdc25C interacts with PCNA at G2/M transition. Oncogene. 2002 Mar 7;21(11):1717-26.
|
| REF 40 |
Involvement of the interaction between p21 and proliferating cell nuclear antigen for the maintenance of G2/M arrest after DNA damage. J Biol Chem. 2001 Nov 16;276(46):42971-7.
|
| REF 41 |
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell. 2004 May 21;14(4):491-500.
|
| REF 42 |
Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Mol Cell. 2010 Feb 12;37(3):396-407.
|
| REF 43 |
The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol in response to oxidative DNA damage in human cells. Mol Cell. 2011 Aug 19;43(4):649-62.
|
| REF 44 |
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. J Biol Chem. 2004 Nov 12;279(46):48360-8.
|
| REF 45 |
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Mol Cell. 2010 Jan 15;37(1):79-89.
|
| REF 46 |
Aberrant C-terminal domain of polymerase targets the functional enzyme to the proteosomal degradation pathway. DNA Repair (Amst). 2015 May;29:154-65.
|
| REF 47 |
NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase in response to oxidative DNA damage. Protein Cell. 2018 Apr;9(4):365-379.
|
| REF 48 |
Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis. Mol Cell Biol. 2011 Oct;31(19):3997-4006.
|
| REF 49 |
Proliferating cell nuclear antigen (PCNA) may function as a double homotrimer complex in the mammalian cell. J Biol Chem. 2005 Apr 8;280(14):13888-94.
|
| REF 50 |
The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function. J Biol Chem. 2004 May 7;279(19):20194-9.
|
| REF 51 |
Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Mol Cell. 2010 Mar 12;37(5):714-27.
|
| REF 52 |
The human homologue of fission Yeast cdc27, p66, is a component of active human DNA polymerase delta. J Biochem. 2001 May;129(5):699-708.
|
| REF 53 |
Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis. Mol Cell. 2014 May 22;54(4):626-38.
|
| REF 54 |
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in -Catenin-Active Cancers. Cell Syst. 2016 Sep 28;3(3):302-316.e4.
|
| REF 55 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 56 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
|
| REF 57 |
Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins. J Biol Chem. 1998 Apr 17;273(16):9561-9.
|
| REF 58 |
S-phase Specific Downregulation of Human O6-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21cip1 Proteins in Glioma Cells. Neoplasia. 2018 Apr;20(4):305-323.
|
| REF 59 |
Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta. J Biol Chem. 2002 Jul 5;277(27):24340-5.
|
| REF 60 |
Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest. Mol Cell Biol. 2006 May;26(9):3527-40.
|
| REF 61 |
c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Pol recruitment to stalled replication forks. Mol Biol Cell. 2012 May;23(10):1943-54.
|
| REF 62 |
Initial crystallographic study of human PCNA in complex with a peptide containing the noncanonical PIP-box sequence of human DNA polymerase iota. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Oct 1;64(Pt 10):954-6.
|
| REF 63 |
Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14256-61.
|
| REF 64 |
Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation. Mol Cell. 2017 Aug 17;67(4):550-565.e5.
|
| REF 65 |
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet. 2000 Jul;25(3):269-77.
|
| REF 66 |
Disruption of Dnmt1/PCNA/UHRF1 interactions promotes tumorigenesis from human and mice glial cells. PLoS One. 2010 Jun 29;5(6):e11333.
|
| REF 67 |
Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science. 1997 Sep 26;277(5334):1996-2000.
|
| REF 68 |
Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry. Biochem Biophys Res Commun. 2005 Dec 2;337(4):1176-84.
|
| REF 69 |
DNA damage tolerance pathway involving DNA polymerase and the tumor suppressor p53 regulates DNA replication fork progression. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4311-9.
|
| REF 70 |
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol. 2001 Aug;21(16):5644-57.
|
| REF 71 |
Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cells. Oncogene. 1998 Mar 12;16(10):1333-43.
|
| REF 72 |
Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Mol Cell. 2007 Jun 22;26(6):843-52.
|
| REF 73 |
Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases. J Biol Chem. 2010 Sep 3;285(36):27900-10.
|
| REF 74 |
Increase of palmitic acid concentration impairs endothelial progenitor cell and bone marrow-derived progenitor cell bioavailability: role of the STAT5/PPAR transcriptional complex. Diabetes. 2013 Apr;62(4):1245-57.
|
| REF 75 |
Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. J Biol Chem. 2009 Oct 16;284(42):28935-42.
|
| REF 76 |
Nuclear translocation of p21(WAF1/CIP1) protein prior to its cytosolic degradation by UV enhances DNA repair and survival. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1361-6.
|
| REF 77 |
Reactivity of anti-proliferating cell nuclear antigen (PCNA) murine monoclonal antibodies and human autoantibodies to the PCNA multiprotein complexes involved in cell proliferation. J Immunol. 2001 Apr 1;166(7):4780-7.
|
| REF 78 |
PIDD orchestrates translesion DNA synthesis in response to UV irradiation. Cell Death Differ. 2011 Jun;18(6):1036-45.
|
| REF 79 |
A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen. Curr Biol. 1995 Mar 1;5(3):275-82.
|
| REF 80 |
A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome. EMBO J. 2001 May 15;20(10):2367-75.
|
| REF 81 |
The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b. Exp Cell Res. 2006 Jan 1;312(1):73-85.
|
| REF 82 |
The human stress-activated protein kin17 belongs to the multiprotein DNA replication complex and associates in vivo with mammalian replication origins. Mol Cell Biol. 2005 May;25(9):3814-30.
|
| REF 83 |
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
|
| REF 84 |
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol Cell. 2004 Aug 27;15(4):595-605.
|
| REF 85 |
The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen. EMBO Rep. 2006 Aug;7(8):817-23.
|
| REF 86 |
Identification of a functional domain in a GADD45-mediated G2/M checkpoint. J Biol Chem. 2000 Nov 24;275(47):36892-8.
|
| REF 87 |
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science. 1994 Nov 25;266(5189):1376-80.
|
| REF 88 |
Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth control. J Biol Chem. 2000 Jun 2;275(22):16810-9.
|
| REF 89 |
Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis. J Biol Chem. 2012 Oct 5;287(41):34225-33.
|
| REF 90 |
Spartan/C1orf124 is important to prevent UV-induced mutagenesis. Cell Cycle. 2012 Sep 15;11(18):3395-402.
|
| REF 91 |
DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks. Nat Struct Mol Biol. 2012 Nov;19(11):1084-92.
|
| REF 92 |
Proliferating cell nuclear antigen in the cytoplasm interacts with components of glycolysis and cancer. FEBS Lett. 2010 Oct 22;584(20):4292-8.
|
| REF 93 |
XRCC1 co-localizes and physically interacts with PCNA. Nucleic Acids Res. 2004 Apr 23;32(7):2193-201.
|
| REF 94 |
p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1. DNA Repair (Amst). 2010 Jun 4;9(6):627-35.
|
