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| Protein General Information |
Top |
| Full Name |
RuvB-like 2 (RUVBL2)
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| UniProt ID |
RUVB2_HUMAN
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| Gene Name |
RUVBL2
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| Gene ID |
10856
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Beta-catenin (CTNNB1) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Hypoxia-inducible factor 1 alpha (HIF-1A) |
Target Info
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PPI Info
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[2] |
| Interacting Patented-recorded Target(s) |
Ubiquitin C-terminal hydrolase UCH37 (UCHL5) |
Target Info
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PPI Info
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[3] |
| Interacting Literature-reported Target(s) |
Proto-oncogene c-Myc (MYC) |
Target Info
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PPI Info
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[4] |
| References |
Top |
| REF 1 |
Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature. 2005 Apr 14;434(7035):921-6.
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| REF 2 |
Negative regulation of hypoxic responses via induced Reptin methylation. Mol Cell. 2010 Jul 9;39(1):71-85.
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| REF 3 |
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol Cell. 2008 Sep 26;31(6):909-17.
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| REF 4 |
Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer. Mol Cancer. 2010 May 30;9:132.
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