Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T82795 Target Info
Target Name Beta-catenin (CTNNB1)
Synonyms Wnt/beta-catenin signaling pathway; PRO2286; OK/SW-cl.35; Catenin beta-1; CTNNB
Target Type Successful Target
Gene Name CTNNB1
Biochemical Class Beta-catenin
UniProt ID
CTNB1_HUMAN 
Target Interacting Proteins  Top
Acid anhydride hydrolases [+] 7 Acid anhydride hydrolases +
Interacting Protein Name RuvB-like 1 (RUVBL1) Interacting Protein Interacting Protein Info
UniProt ID
RUVB1_HUMAN 
Synonyms ECP54; INO80H; NMP238; PONTIN; Pontin52; RVB1; TIH1; TIP49; TIP49A
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Affinity Capture-Western [4]
5 Reconstituted Complex [4]
Interacting Protein Name Chromodomain-helicase-DNA-binding protein 8 (CHD8) Interacting Protein Interacting Protein Info
UniProt ID
CHD8_HUMAN 
Synonyms AUTS18; HELSNF1
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [5]
2 Affinity Capture-Western [6]
3 Reconstituted Complex [5]
4 Reconstituted Complex [6]
Interacting Protein Name Sucrose nonfermenting protein 2 homolog (SMARCA5) Interacting Protein Interacting Protein Info
UniProt ID
SMCA5_HUMAN 
Synonyms ISWI; SNF2H; WCRF135; hISWI; hSNF2H
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-MS [3]
4 Reconstituted Complex [1]
Interacting Target Name ATP-dependent RNA helicase DDX5 (DDX5) Clinical trial Target Interacting Protein Info
UniProt ID
DDX5_HUMAN 
Synonyms RNA helicase p68; Probable ATP-dependent RNA helicase DDX5; HLR1; HELR; G17P1; DEAD box protein 5
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [7]
Interacting Protein Name RuvB-like 2 (RUVBL2) Interacting Protein Interacting Protein Info
UniProt ID
RUVB2_HUMAN 
Synonyms ECP51; INO80J; REPTIN; RVB2; TIH2; TIP48; TIP49B
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [8]
3 Co-localization [8]
Interacting Protein Name ATP-dependent RNA helicase DDX1 (DDX1) Interacting Protein Interacting Protein Info
UniProt ID
DDX1_HUMAN 
Synonyms DBP.RB; UKVH5d
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
Interacting Protein Name ATP-dependent RNA helicase A (DHX9) Interacting Protein Interacting Protein Info
UniProt ID
DHX9_HUMAN 
Synonyms DDX9; LKP; NDH2; NDHII; RHA
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
Acyltransferases [+] 5 Acyltransferases +
Interacting Target Name Histone acetyltransferase p300 (EP300) Clinical trial Target Interacting Protein Info
UniProt ID
EP300_HUMAN 
Synonyms Protein propionyltransferase p300; p300 HAT; P300; Histone crotonyltransferase p300; Histone butyryltransferase p300; E1A-associated protein p300; E1Aassociated protein p300
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Luminescence [9]
2 Affinity Capture-Western [9]
3 Biochemical Activity [10]
4 Reconstituted Complex [9]
Interacting Target Name Signal transduction protein CBL (CBL) Literature-reported Target Interacting Protein Info
UniProt ID
CBL_HUMAN 
Synonyms RNF55; RING-type E3 ubiquitin transferase CBL; RING finger protein 55; Proto-oncogene c-CBL; E3 ubiquitin-protein ligase CBL; C-Cbl; CBL2; Casitas B-lineage lymphoma proto-oncogene
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [11]
2 Biochemical Activity [11]
Interacting Protein Name E3 ubiquitin-protein ligase HUWE1 (HUWE1) Interacting Protein Interacting Protein Info
UniProt ID
HUWE1_HUMAN 
Synonyms ARF.BP1; HECTH9; HSPC272; Ib772; LASU1; MULE; URE.B1; UREB1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [12]
Interacting Protein Name Histone acetyltransferase KAT2A (KAT2A) Interacting Protein Interacting Protein Info
UniProt ID
KAT2A_HUMAN 
Synonyms GCN5; GCN5L2; PCAF.b; hGCN5
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [13]
2 Reconstituted Complex [1]
Interacting Protein Name E3 SUMO-protein ligase RanBP2 (RANBP2) Interacting Protein Interacting Protein Info
UniProt ID
RBP2_HUMAN 
Synonyms ADANE; ANE1; IIAE3; NUP358; TRP1; TRP2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [14]
Auxiliary transporters [+] 1 Auxiliary transporters +
Interacting Protein Name 14-3-3 protein zeta/delta (YWHAZ) Interacting Protein Interacting Protein Info
UniProt ID
1433Z_HUMAN 
Synonyms 14.3.3.zeta; HEL.S.3; HEL4; KCIP.1; YWHAD
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [16]
4 Affinity Capture-Western [15]
Carbon-nitrogen hydrolases [+] 2 Carbon-nitrogen hydrolases +
Interacting Target Name Histone deacetylase 1 (HDAC1) Successful Target Interacting Protein Info
UniProt ID
HDAC1_HUMAN 
Synonyms RPD3L1; HD1
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [17]
3 Affinity Capture-Western [18]
4 Affinity Capture-Western [19]
Interacting Target Name Histone deacetylase 7 (HDAC7) Patented-recorded Target Interacting Protein Info
UniProt ID
HDAC7_HUMAN 
Synonyms Histone deacetylase 7A; HDAC7A; HD7a; HD7
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [20]
3 Affinity Capture-Western [21]
4 Co-localization [20]
Ester hydrolases [+] 1 Ester hydrolases +
Interacting Protein Name Histidine triad nucleotide-binding protein 1 (HINT1) Interacting Protein Interacting Protein Info
UniProt ID
HINT1_HUMAN 
Synonyms HINT; NMAN; PKCI.1; PRKCNH1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [22]
2 Yeast two hybrid [23]
Heat shock proteins [+] 2 Heat shock proteins +
Interacting Target Name Heat shock protein 90 beta (HSP90B) Clinical trial Target Interacting Protein Info
UniProt ID
HS90B_HUMAN 
Synonyms HSP84; HSP 84; Heat shock 84 kDa
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Interacting Target Name Lipopolysaccharide-associated protein 1 (HSPA8) Literature-reported Target Interacting Protein Info
UniProt ID
HSP7C_HUMAN 
Synonyms LPS-associated protein 1; LAP-1; HSPA10; HSP73; HSC70; Heat shock protein 73; Heat shock cognate 71 kDa protein; Heat shock 70 kDa protein 8
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Intermediate filaments [+] 1 Intermediate filaments +
Interacting Protein Name Lamin-B1 (LMNB1) Interacting Protein Interacting Protein Info
UniProt ID
LMNB1_HUMAN 
Synonyms ADLD; LMN; LMN2; LMNB
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [24]
Isomerases [+] 1 Isomerases +
Interacting Target Name DNA topoisomerase II alpha (TOP2A) Clinical trial Target Interacting Protein Info
UniProt ID
TOP2A_HUMAN 
Synonyms TOP2; DNA topoisomerase II, alpha isozyme; DNA topoisomerase 2-alpha; DNA topoisomerase 2alpha
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [7]
Kinases [+] 9 Kinases +
Interacting Target Name Glycogen synthase kinase-3 beta (GSK-3B) Clinical trial Target Interacting Protein Info
UniProt ID
GSK3B_HUMAN 
Synonyms Serine/threonine-protein kinase GSK3B; GSK-3 beta
Evidence Score (E-score) 10 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [25]
3 Affinity Capture-Western [26]
4 Affinity Capture-Western [27]
5 Affinity Capture-Western [28]
6 Affinity Capture-Western [29]
7 Affinity Capture-Western [30]
8 Affinity Capture-Western [31]
9 Biochemical Activity [32]
10 Co-localization [33]
Interacting Target Name Erbb2 tyrosine kinase receptor (HER2) Successful Target Interacting Protein Info
UniProt ID
ERBB2_HUMAN 
Synonyms Tyrosine kinase-type cell surface receptor HER2; Tyrosine kinase receptor ErbB2; Receptor tyrosine-protein kinase erbB-2; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; P185erbB2; NGL; NEU proto-oncogene; NEU; MLN19; MLN 19; Metastatic lymph node gene 19 protein; HER2/neu; HER2 (erbB2/neu); HER-2; Erb2; Epidermal growth factor receptor 2; C-erbB-2 oncoprotein; C-erbB-2; CD340
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [34]
2 Co-localization [34]
3 Far Western [35]
4 Reconstituted Complex [35]
Interacting Protein Name Transformation/transcription domain-associated protein (TRRAP) Interacting Protein Interacting Protein Info
UniProt ID
TRRAP_HUMAN 
Synonyms PAF350/400; PAF400; STAF40; TR.AP; Tra1
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Affinity Capture-Western [36]
4 Reconstituted Complex [1]
Interacting Target Name Epidermal growth factor receptor (EGFR) Successful Target Interacting Protein Info
UniProt ID
EGFR_HUMAN 
Synonyms Epidermal growth factor receptor variant III; Proto-oncogene c-ErbB-1 variant III; Receptor tyrosine-protein kinase erbB-1 variant III; EGFR variant III; ERBB variant III; ERBB1 variant III; HER1 variant III
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [37]
2 Affinity Capture-Western [34]
3 Reconstituted Complex [38]
Interacting Target Name Fibroblast growth factor receptor 1 (FGFR1) Successful Target Interacting Protein Info
UniProt ID
FGFR1_HUMAN 
Synonyms N-sam; HBGFR; Fms-like tyrosine kinase 2; FLT-2; FLT2; FLG; FGFR-1; FGFBR; c-fgr; CEK; CD331 antigen; CD331; bFGF-R-1; bFGF-R; BFGFR; Basic fibroblast growth factor receptor 1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [39]
2 Co-localization [33]
Interacting Target Name Fyn tyrosine protein kinase (FYN) Successful Target Interacting Protein Info
UniProt ID
FYN_HUMAN 
Synonyms Tyrosine-protein kinase Fyn; Src-like kinase; SLK; Proto-oncogene tyrosine-protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Fyn Protooncogene Syn; Fyn p59-Fyn
Evidence Score (E-score) 2 Experimental Evidences +
1 Biochemical Activity [40]
2 Co-localization [33]
Interacting Target Name Glycogen synthase kinase-3 alpha (GSK-3A) Successful Target Interacting Protein Info
UniProt ID
GSK3A_HUMAN 
Synonyms Serine/threonine-protein kinase GSK3A; Serine/threonineprotein kinase GSK3A; GSK-3 alpha; GSK3 alpha; GSK-3; Glycogen synthase kinase3 alpha; Glycogen synthase kinase 3
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [41]
2 Biochemical Activity [42]
Interacting Target Name Pyruvate kinase M2 (PKM) Clinical trial Target Interacting Protein Info
UniProt ID
KPYM_HUMAN 
Synonyms Tumor M2-PK; Thyroid hormone-binding protein 1; THBP1; Pyruvate kinase PKM; Pyruvate kinase muscle isozyme; Pyruvate kinase isozymes M1/M2; Pyruvate kinase 2/3; PKM2; PK3; PK2; p58; Opa-interacting protein 3; OIP-3; OIP3; Cytosolic thyroid hormone-binding protein; CTHBP
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Reconstituted Complex [43]
Interacting Target Name Large tumor suppressor homolog 2 (LATS2) Literature-reported Target Interacting Protein Info
UniProt ID
LATS2_HUMAN 
Synonyms Warts-like kinase; Serine/threonine-protein kinase LATS2; Serine/threonine-protein kinase kpm; KPM; Kinase phosphorylated during mitosis protein
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [44]
2 Proximity Label-MS [45]
Nuclear hormone receptors [+] 3 Nuclear hormone receptors +
Interacting Target Name Androgen receptor (AR) Successful Target Interacting Protein Info
UniProt ID
ANDR_HUMAN 
Synonyms Testosterone receptor; Nuclear receptor subfamily 3 group C member 4; NR3C4; Dihydrotestosterone receptor; DHTR; Androgen receptor
Evidence Score (E-score) 6 Experimental Evidences +
1 Affinity Capture-Western [46]
2 Affinity Capture-Western [47]
3 Reconstituted Complex [48]
4 Reconstituted Complex [46]
5 Reconstituted Complex [10]
6 Yeast two hybrid [48]
Interacting Target Name Retinoic acid receptor RXR-alpha (RXRA) Successful Target Interacting Protein Info
UniProt ID
RXRA_HUMAN 
Synonyms RXRalpha; Retinoid X receptor alpha; Nuclear receptor subfamily 2 group B member 1; NR2B1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [49]
3 Co-localization [33]
Interacting Target Name Hepatocyte nuclear factor 4-alpha (HNF4A) Literature-reported Target Interacting Protein Info
UniProt ID
HNF4A_HUMAN 
Synonyms Transcription factor HNF-4; Transcription factor 14; TCF-14; TCF14; Nuclear receptor subfamily 2 group A member 1; NR2A1; HNF-4-alpha; HNF4
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [46]
2 Co-localization [33]
One-carbon transferases [+] 2 One-carbon transferases +
Interacting Target Name Mixed-lineage leukemia protein (MLL) Literature-reported Target Interacting Protein Info
UniProt ID
KMT2A_HUMAN 
Synonyms Zinc finger protein HRX; Trithorax-like protein; Trithoraxlike protein; p320; p180; Myeloid/lymphoid or mixed-lineage leukemia protein 1; Myeloid/lymphoid or mixed-lineage leukemia; MLL1; MLL cleavage product C180; Lysine N-methyltransferase 2A; Lysine Nmethyltransferase 2A; HTRX; HRX; Histonelysine Nmethyltransferase MLL; Histone-lysine N-methyltransferase 2A; CXXC-type zinc finger protein 7; CXXCtype zinc finger protein 7; CXXC7; ALL-1; ALL1
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Affinity Capture-MS [2]
3 Reconstituted Complex [1]
4 Reconstituted Complex [2]
Interacting Target Name Enhancer of zeste homolog 2 (EZH2) Successful Target Interacting Protein Info
UniProt ID
EZH2_HUMAN 
Synonyms Lysine N-methyltransferase 6; Lysine Nmethyltransferase 6; KMT6; Histone-lysine N-methyltransferase EZH2; Histonelysine Nmethyltransferase EZH2; EZH2 Y641N mutations; EZH2 Y641F mutations; ENX-1; ENX1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [50]
2 Reconstituted Complex [51]
Oxidoreductases [+] 1 Oxidoreductases +
Interacting Protein Name L-lactate dehydrogenase B chain (LDHB) Interacting Protein Interacting Protein Info
UniProt ID
LDHB_HUMAN 
Synonyms HEL.S.281; LDH.B; LDH.H; LDHBD; TRG.5
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Peptidases [+] 2 Peptidases +
Interacting Target Name Presenilin 1 (PSEN1) Clinical trial Target Interacting Protein Info
UniProt ID
PSN1_HUMAN 
Synonyms S182 protein; PSNL1; PS-1; PS1; Protein S182; Presenilin-1; AD3
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-Western [52]
2 Affinity Capture-Western [53]
3 Affinity Capture-Western [54]
4 Affinity Capture-Western [55]
5 Reconstituted Complex [53]
Interacting Protein Name Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) Interacting Protein Interacting Protein Info
UniProt ID
USP9X_HUMAN 
Synonyms DFFRX; FAF; FAM; MRX99
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [56]
2 Affinity Capture-Western [57]
3 Reconstituted Complex [58]
Ribosomal proteins [+] 2 Ribosomal proteins +
Interacting Target Name Laminin receptor 37/67kDa (LRP/LR) Patented-recorded Target Interacting Protein Info
UniProt ID
RSSA_HUMAN 
Synonyms Small ribosomal subunit protein uS2; NEM/1CHD4; Multidrug resistance-associated protein MGr1-Ag; LBP/p40; LAMR1; LamR; Laminin-binding protein precursor p40; Laminin receptor 1; LAMBR; Colon carcinoma laminin-binding protein; 67LR; 67 kDa laminin receptor; 40S ribosomal protein SA; 37LRP; 37/67 kDa laminin receptor; 37 kDa laminin receptor precursor
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Interacting Protein Name Large ribosomal subunit protein P2 (RPLP2) Interacting Protein Interacting Protein Info
UniProt ID
RLA2_HUMAN 
Synonyms D11S2243E; LP2; P2; RPP2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Transcription regulators [+] 10 Transcription regulators +
Interacting Protein Name Transcription factor 4 (TCF4) Interacting Protein Interacting Protein Info
UniProt ID
ITF2_HUMAN 
Synonyms E2.2; ITF.2; ITF2; PTHS; SEF.2; SEF2; SEF2.1; SEF2.1A; SEF2.1B; SEF2.1D; TCF.4; bHLHb19
Evidence Score (E-score) 15 Experimental Evidences +
1 Affinity Capture-MS [59]
2 Affinity Capture-Western [60]
3 Affinity Capture-Western [61]
4 Affinity Capture-Western [62]
5 Affinity Capture-Western [10]
6 Affinity Capture-Western [63]
7 Affinity Capture-Western [29]
8 Affinity Capture-Western [64]
9 Affinity Capture-Western [65]
10 Affinity Capture-Western [66]
11 Reconstituted Complex [67]
12 Reconstituted Complex [10]
13 Reconstituted Complex [68]
14 Reconstituted Complex [69]
15 Yeast two hybrid [70]
Interacting Protein Name Lymphoid enhancer-binding factor 1 (LEF1) Interacting Protein Interacting Protein Info
UniProt ID
LEF1_HUMAN 
Synonyms LEF.1; TCF10; TCF1ALPHA; TCF7L3
Evidence Score (E-score) 13 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [71]
3 Affinity Capture-Western [72]
4 Affinity Capture-Western [73]
5 Affinity Capture-Western [29]
6 Affinity Capture-Western [17]
7 Affinity Capture-Western [18]
8 Affinity Capture-Western [74]
9 Affinity Capture-Western [75]
10 Co-localization [76]
11 Reconstituted Complex [77]
12 Reconstituted Complex [78]
13 Yeast two hybrid [79]
Interacting Target Name Transcription factor 7-like 2 (TCF7L2) Literature-reported Target Interacting Protein Info
UniProt ID
TF7L2_HUMAN 
Synonyms TCF-4; TCF4; T-cell-specific transcription factor 4; T-cell transcription factor-4; T-cell factor 4; HTCF-4; HMG box transcription factor 4
Evidence Score (E-score) 8 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [80]
3 Affinity Capture-Western [27]
4 Affinity Capture-Western [7]
5 Affinity Capture-Western [81]
6 Co-crystal Structure [82]
7 Co-localization [83]
8 Reconstituted Complex [84]
Interacting Target Name Transcription factor Sp1 (SP1) Clinical trial Target Interacting Protein Info
UniProt ID
SP1_HUMAN 
Synonyms TSFP1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [28]
2 Affinity Capture-Western [61]
3 Reconstituted Complex [28]
Interacting Target Name DNA-binding factor KBF1 (p105) Clinical trial Target Interacting Protein Info
UniProt ID
NFKB1_HUMAN 
Synonyms Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor of kappa light polypeptide gene enhancer in Bcells 1; Nuclear factor NFkappaB p50 subunit; Nuclear factor NF-kappa-B p105 subunit; Nuclear factor NFkappaB p105 subunit; EBP-1; EBP1; DNA-binding factor KBF1; DNAbinding factor KBF1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [8]
2 Co-localization [8]
Interacting Target Name Mothers against decapentaplegic homolog 7 (SMAD7) Clinical trial Target Interacting Protein Info
UniProt ID
SMAD7_HUMAN 
Synonyms Smad7; SMAD family member 7; SMAD 7; Mothers against DPP homolog 8; Mothers against decapentaplegic homolog 8; MAD homolog 8; hSMAD7
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [71]
2 Co-localization [71]
Interacting Target Name Transcription factor SOX-2 (SOX2) Literature-reported Target Interacting Protein Info
UniProt ID
SOX2_HUMAN 
Synonyms ANOP3; MCOPS3; SRY-box 2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [85]
2 Affinity Capture-Western [86]
Interacting Protein Name Transcription factor BTF3 (BTF3) Interacting Protein Interacting Protein Info
UniProt ID
BTF3_HUMAN 
Synonyms BETA.NAC; BTF3a; BTF3b; NACB
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Interacting Protein Name Mothers against decapentaplegic homolog 2 (SMAD2) Interacting Protein Interacting Protein Info
UniProt ID
SMAD2_HUMAN 
Synonyms JV18; JV18.1; MADH2; MADR2; hMAD.2; hSMAD2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [87]
Interacting Protein Name Transcription factor 7-like 1 (TCF7L1) Interacting Protein Interacting Protein Info
UniProt ID
TF7L1_HUMAN 
Synonyms TCF.3; TCF3
Evidence Score (E-score) 2 Experimental Evidences +
1 Co-crystal Structure [88]
2 Protein-peptide [89]
Other proteins [+] 29 Other proteins +
Interacting Target Name Epithelial cadherin (CDH1) Literature-reported Target Interacting Protein Info
UniProt ID
CADH1_HUMAN 
Synonyms Uvomorulin; UVO; E-cadherin gene; E-cadherin; CDHE; CD324; CAM 120/80; Cadherin-1
Evidence Score (E-score) 20 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [90]
3 Affinity Capture-Western [91]
4 Affinity Capture-Western [92]
5 Affinity Capture-Western [93]
6 Affinity Capture-Western [94]
7 Affinity Capture-Western [95]
8 Affinity Capture-Western [61]
9 Affinity Capture-Western [40]
10 Affinity Capture-Western [96]
11 Affinity Capture-Western [97]
12 Affinity Capture-Western [98]
13 Affinity Capture-Western [99]
14 Affinity Capture-Western [100]
15 Affinity Capture-Western [101]
16 Affinity Capture-Western [102]
17 Affinity Capture-Western [63]
18 Co-crystal Structure [103]
19 Co-localization [61]
20 Fluorescence Resonance Energy Transfer [104]
Interacting Protein Name F-box/WD repeat-containing protein 1A (BTRC) Interacting Protein Interacting Protein Info
UniProt ID
FBW1A_HUMAN 
Synonyms BETA.TRCP; FBW1A; FBXW1; FBXW1A; FWD1; bTrCP; bTrCP1; betaTrCP
Evidence Score (E-score) 20 Experimental Evidences +
1 Affinity Capture-Western [105]
2 Affinity Capture-Western [106]
3 Affinity Capture-Western [107]
4 Affinity Capture-Western [28]
5 Affinity Capture-Western [108]
6 Affinity Capture-Western [109]
7 Affinity Capture-Western [16]
8 Affinity Capture-Western [110]
9 Affinity Capture-Western [111]
10 Affinity Capture-Western [112]
11 Affinity Capture-Western [113]
12 Affinity Capture-Western [114]
13 Affinity Capture-Western [115]
14 Affinity Capture-Western [116]
15 Protein-Fragment Complementation Assay [117]
16 Protein-Fragment Complementation Assay [118]
17 Protein-peptide [119]
18 Reconstituted Complex [106]
19 Reconstituted Complex [120]
20 Reconstituted Complex [121]
Interacting Protein Name Adenomatous polyposis coli protein (APC) Interacting Protein Interacting Protein Info
UniProt ID
APC_HUMAN 
Synonyms BTPS2; DP2; DP2.5; DP3; GS; PPP1R46
Evidence Score (E-score) 13 Experimental Evidences +
1 Affinity Capture-MS [41]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [90]
4 Affinity Capture-Western [25]
5 Affinity Capture-Western [122]
6 Affinity Capture-Western [26]
7 Affinity Capture-Western [27]
8 Co-crystal Structure [123]
9 Co-crystal Structure [89]
10 Protein-peptide [89]
11 Reconstituted Complex [124]
12 Reconstituted Complex [123]
13 Reconstituted Complex [89]
Interacting Protein Name Axin-1 (AXIN1) Interacting Protein Interacting Protein Info
UniProt ID
AXIN1_HUMAN 
Synonyms AXIN; PPP1R49
Evidence Score (E-score) 8 Experimental Evidences +
1 Affinity Capture-Western [125]
2 Affinity Capture-Western [27]
3 Affinity Capture-Western [106]
4 Affinity Capture-Western [107]
5 Affinity Capture-Western [28]
6 Reconstituted Complex [125]
7 Reconstituted Complex [106]
8 Yeast two hybrid [125]
Interacting Protein Name Catenin alpha-1 (CTNNA1) Interacting Protein Interacting Protein Info
UniProt ID
CTNA1_HUMAN 
Synonyms CAP102
Evidence Score (E-score) 7 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
3 Affinity Capture-MS [41]
4 Affinity Capture-MS [59]
5 Affinity Capture-Western [96]
6 Affinity Capture-Western [40]
7 Reconstituted Complex [126]
Interacting Target Name Junction plakoglobin (JUP) Literature-reported Target Interacting Protein Info
UniProt ID
PLAK_HUMAN 
Synonyms Plakoglobin; DP3; Desmoplakin-3; Desmoplakin III; CTNNG; Catenin gamma
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [41]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [90]
4 Affinity Capture-Western [38]
5 Co-localization [33]
Interacting Target Name Mucin-1 (MUC1) Clinical trial Target Interacting Protein Info
UniProt ID
MUC1_HUMAN 
Synonyms Tumour-associated antigen mucin 1; Tumor-associated mucin; Tumor-associated epithelial membraneantigen; Tumor-associated epithelial membrane antigen; PUM; Polymorphic epithelial mucin; PEMT; PEM; Peanut-reactive urinary mucin; Mucin-1; MUC-1; Krebs von den Lungen-6; KL-6; H23AG; Episialin; EMA; CD227 antigen; CD227; Carcinoma-associated mucin; Cancer antigen 15-3; CA 15-3; Breast carcinoma-associated antigen DF3
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [127]
2 Affinity Capture-Western [128]
3 Reconstituted Complex [128]
4 Reconstituted Complex [129]
Interacting Protein Name S-phase kinase-associated protein 1 (SKP1) Interacting Protein Interacting Protein Info
UniProt ID
SKP1_HUMAN 
Synonyms EMC19; OCP.II; OCP2; SKP1A; TCEB1L; p19A
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [130]
3 Affinity Capture-Western [111]
4 Protein-peptide [119]
Interacting Target Name Placental cadherin (CDH3) Clinical trial Target Interacting Protein Info
UniProt ID
CADH3_HUMAN 
Synonyms P-cadherin; Pcadherin; CDHP; Cadherin-3
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [100]
3 Co-purification [131]
Interacting Target Name Adenomatous polyposis coli 2 (APC2) Literature-reported Target Interacting Protein Info
UniProt ID
APCL_HUMAN 
Synonyms APC-like; APClike; APCL; Adenomatous polyposis coli protein-like; Adenomatous polyposis coli proteinlike; Adenomatous polyposis coli protein 2
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [132]
2 Reconstituted Complex [2]
3 Yeast two hybrid [120]
Interacting Protein Name Beta-catenin-interacting protein 1 (CTNNBIP1) Interacting Protein Interacting Protein Info
UniProt ID
CNBP1_HUMAN 
Synonyms ICAT
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [59]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [24]
Interacting Protein Name Catenin delta-1 (CTNND1) Interacting Protein Interacting Protein Info
UniProt ID
CTND1_HUMAN 
Synonyms CAS; CTNND; P120CAS; P120CTN; p120; p120(CAS); p120(CTN)
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [90]
3 Affinity Capture-Western [38]
Interacting Protein Name Emerin (EMD) Interacting Protein Interacting Protein Info
UniProt ID
EMD_HUMAN 
Synonyms EDMD; LEMD5; STA
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [133]
3 Reconstituted Complex [133]
Interacting Protein Name Four and a half LIM domains protein 2 (FHL2) Interacting Protein Interacting Protein Info
UniProt ID
FHL2_HUMAN 
Synonyms AAG11; DRAL; FHL.2; SLIM.3; SLIM3
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Reconstituted Complex [134]
3 Yeast two hybrid [134]
Interacting Protein Name Non-POU domain-containing octamer-binding protein (NONO) Interacting Protein Interacting Protein Info
UniProt ID
NONO_HUMAN 
Synonyms NMT55; NRB54; P54; P54NRB; PPP1R114
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [7]
Interacting Protein Name Retinoblastoma-binding protein 5 (RBBP5) Interacting Protein Interacting Protein Info
UniProt ID
RBBP5_HUMAN 
Synonyms RBQ3; SWD1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [13]
2 Reconstituted Complex [1]
3 Reconstituted Complex [2]
Interacting Protein Name Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) Interacting Protein Interacting Protein Info
UniProt ID
ROA1_HUMAN 
Synonyms Single-strand RNA-binding protein; HNRPA1; hnRNP core protein A1; hnRNP A1; Heterogeneous nuclear ribonucleoprotein A1; Helix-destabilizing protein
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [7]
Interacting Protein Name Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) Interacting Protein Interacting Protein Info
UniProt ID
ROA2_HUMAN 
Synonyms HNRPA2B1; hnRNP A2/B1; Heterogeneous nuclear ribonucleoproteins A2/B1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
3 Affinity Capture-Western [7]
Interacting Protein Name Vinculin (VCL) Interacting Protein Interacting Protein Info
UniProt ID
VINC_HUMAN 
Synonyms CMD1W; CMH15; HEL114; MV; MVCL
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [135]
3 Affinity Capture-Western [136]
Interacting Target Name Poly [ADP-ribose] polymerase 1 (PARP1) Successful Target Interacting Protein Info
UniProt ID
PARP1_HUMAN 
Synonyms Protein poly-ADP-ribosyltransferase PARP1; PPOL; Poly[ADP-ribose] synthetase-1; Poly[ADP-ribose] synthase 1; Poly(ADP-ribose)polymerase-1; PARP-1; NAD(+)Poly [ADP-ribose] polymerase-1 ADP-ribosyltransferase-1; NAD(+) ADP-ribosyltransferase-1; NAD(+) ADP-ribosyltransferase 1; DNA ADP-ribosyltransferase PARP1; ARTD1; ADPRT 1; ADPRT; ADP-ribosyltransferase diphtheria toxin-like 1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
Interacting Target Name Neural cadherin (CDH2) Clinical trial Target Interacting Protein Info
UniProt ID
CADH2_HUMAN 
Synonyms N-cadherin; NCAD; CDw325; CDHN; CD325; Cadherin-2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [137]
2 Affinity Capture-Western [138]
Interacting Target Name Vascular endothelial cadherin (CDH5) Literature-reported Target Interacting Protein Info
UniProt ID
CADH5_HUMAN 
Synonyms VE-cadherin; VE-cad; CD144 antigen; CD144; Cadherin-5; 7B4 antigen
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [139]
2 Affinity Capture-Western [140]
Interacting Target Name ELAV-like protein 1 (ELAVL1) Literature-reported Target Interacting Protein Info
UniProt ID
ELAV1_HUMAN 
Synonyms HuR; Hu-antigen R
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Reconstituted Complex [141]
Interacting Target Name Platelet endothelial cell adhesion molecule (PECAM1) Literature-reported Target Interacting Protein Info
UniProt ID
PECA1_HUMAN 
Synonyms PECAM-1; PECA1; GPIIA'; EndoCAM; ECAM; CD31 antigen; CD31
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [142]
2 Co-localization [33]
Interacting Protein Name Cadherin-10 (CDH10) Interacting Protein Interacting Protein Info
UniProt ID
CAD10_HUMAN 
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [41]
2 Affinity Capture-Western [143]
Interacting Protein Name Heterogeneous nuclear ribonucleoprotein K (HNRNPK) Interacting Protein Interacting Protein Info
UniProt ID
HNRPK_HUMAN 
Synonyms CSBP; HNRPK; TUNP
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-Western [7]
Interacting Protein Name Heterogeneous nuclear ribonucleoprotein M (HNRNPM) Interacting Protein Interacting Protein Info
UniProt ID
HNRPM_HUMAN 
Synonyms CEAR; HNRNPM4; HNRPM; HNRPM4; HTGR1; NAGR1; hnRNP M
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
Interacting Protein Name Plasminogen activator inhibitor 1 RNA-binding protein (SERBP1) Interacting Protein Interacting Protein Info
UniProt ID
PAIRB_HUMAN 
Synonyms CHD3IP; HABP4L; PAI.RBP1; PAIRBP1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [15]
2 Affinity Capture-MS [3]
Interacting Protein Name Pre-mRNA-processing factor 6 (PRPF6) Interacting Protein Interacting Protein Info
UniProt ID
PRP6_HUMAN 
Synonyms ANT.1; ANT1; C20orf14; Prp6; RP60; SNRNP102; TOM; U5.102K; hPrp6
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [7]
2 Affinity Capture-MS [3]
References  Top
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