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| Protein General Information (TTD Target) |
Top |
| Full Name |
Target of rapamycin complex 2 MAPKAP1 (MTORC2)
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Clinical trial
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Target Info
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| UniProt ID |
SIN1_HUMAN
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| Gene Name |
MAPKAP1
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| Gene ID |
79109
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| References |
Top |
| REF 1 |
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40. Nat Cell Biol. 2007 Mar;9(3):316-23.
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| REF 2 |
Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit. Elife. 2017 Mar 7;6. pii: e19594.
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| REF 3 |
Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Mol Cell. 2010 Sep 10;39(5):797-808.
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