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Protein General Information |
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Full Name |
Structure-specific endonuclease subunit SLX4 (SLX4)
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UniProt ID |
SLX4_HUMAN
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Gene Name |
SLX4
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Gene ID |
84464
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
Polo-like kinase 1 (PLK1) |
Target Info
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PPI Info
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[1] |
Interacting Literature-reported Target(s) |
Telomeric repeat-binding factor 2 (TERF2) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Cell. 2009 Jul 10;138(1):63-77.
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REF 2 |
Localization-dependent and -independent roles of SLX4 in regulating telomeres. Cell Rep. 2013 Sep 12;4(5):853-60.
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