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| Protein General Information (TTD Target) |
Top |
| Full Name |
Tankyrase-2 (TNKS-2)
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Clinical trial
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Target Info
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| UniProt ID |
TNKS2_HUMAN
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| Gene Name |
TNKS2
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| Gene ID |
80351
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| Interacting TTD Target Information |
Top |
| Interacting Patented-recorded Target(s) |
Leucyl-cysteinyl aminopeptidase (LNPEP) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Telomeric repeat-binding factor 1 (TERF1) |
Target Info
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PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase). Biochem J. 2002 Feb 1;361(Pt 3):451-9.
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| REF 2 |
Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles. J Biol Chem. 2000 Dec 8;275(49):38437-44.
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