Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T40954 | Target Info | |||
| Target Name | Xanthine dehydrogenase/oxidase (XDH) | ||||
| Synonyms |
Xanthine oxidase; Xanthine dehydrogenase; XDHA
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| Target Type | Successful Target | ||||
| Gene Name | XDH | ||||
| Biochemical Class | CH/CH(2) oxidoreductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 118 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Isovanillin
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|
Approved | Compound Info | ||
| Synonyms |
Isovanilin; Isovanilline; Iso-Vanillin; Oxy-3 methoxy-4 benzaldehyde; Oxy-3 methoxy-4 benzaldehyde [French]; P-Anisaldehyde, 3-hydroxy-(8CI); 3-Hydroxy-4-methoxybenzaldehyde; 3-Hydroxy-p-anisaldehyde; 3-Hydroxyanisaldehyde; 3-hydroxy-4-anisaldehyde; 4-Methoxy-3-hydroxybenzaldehyde; 5-Formylguaiacol
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Thioguanine
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Approved | Compound Info | ||
| Synonyms |
6-thioguanine; Lanvis; THG; Tabloid; ThioguaninGSK; Tioguanin; Tioguanina; Tioguanine; Tioguaninum; Glaxo Wellcome Brand of Thioguanine; Glaxo Wellcome Brand of Tioguanine; GlaxoSmithKline Brand of Thioguanine; GlaxoSmithKline Brand of Tioguanine; Thioguanin GSK; Thioguanine Hemihydrate; Thioguanine Monosodium Salt; Thioguanine Tabloid; Tioguanina Wellcome; Tioguanine GlaxoSmithKline Brand; Wellcome Brand of Thioguanine; BW 5071; DX4; LT00455187; Wellcome U3B; Lanvis (TN); Thioguanin-GSK; Thioguanine [USAN:BAN]; Tioguanina[INN-Spanish]; Tioguanine (INN); Tioguaninum [INN-Latin]; Purine antimetabolite: antimetabolite: inhibits nucleic acid replication; Guanine, thio-(VAN); 2 Amino 6 Purinethiol; 2-Amino 6MP; 2-Amino-1,7-dihydro-6H-purin-6-thion; 2-Amino-1,7-dihydro-6H-purin-6-thion [Czech]; 2-Amino-1,7-dihydro-6H-purine-6-thione; 2-Amino-6-MP; 2-Amino-6-mercaptopurine; 2-Amino-6-merkaptopurin; 2-Amino-6-merkaptopurin [Czech]; 2-Amino-6-purinethiol; 2-Amino-9H-purine-6-thiol; 2-Aminopurin-6-thiol; 2-Aminopurin-6-thiol [Czech]; 2-Aminopurine-6(1H)-thione; 2-Aminopurine-6-thiol; 2-Thioguanine; 2-amino-3,7-dihydropurine-6-thione; 6 Thioguanine; 6-Mercapto-2-aminopurine; 6-Mercaptoguanine; 6-TG; 6-Thioguanine; 6-Thioguanine (6-TG); 6-Thioguanine, Thioguanine; Thioguanine (Guanine analog)
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| Activity |
IC50 = 92420 nM
|
[2] | |||
| Compound Name |
CONTIGOSIDE B
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Phase 2/3 | Compound Info | ||
| Synonyms |
Isoquercitrin; Isoquercetin; 482-35-9; Hirsutrin; 3-Glucosylquercetin; Glucosyl 3-quercetin; Quercetin 3-glucoside; Quercetol 3-glucoside; Quercetin 3-o-glucopyranoside; Quercetin 3-D-glucoside; Quercetol 3-monoglucoside; Quercetin 3-monoglucoside; Isotrifoliin; Quercetin 3-beta-glucoside; Quercetin 3-O-glucoside; quercetin-3-glucoside; Quercetin 3-beta-O-glucoside; Quercetin-3-O-glucopyranoside; UNII-6HN2PC637T; quercetin-3-O-glucoside; NSC 115918; BRN 0100989; CHEMBL250450; 6HN2PC637T; CHEBI:68352; quercetin 3-O-beta-D-glucopyran
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
EPICATECHIN
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Phase 2 | Compound Info | ||
| Synonyms |
(-)-Epicatechin; Epicatechin; 490-46-0; L-Epicatechin; (-)-Epicatechol; l-Acacatechin; (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol; Epicatechol; l-Epicatechol; (-)epicatechin; (2R,3R)-(-)-Epicatechin; UNII-34PHS7TU43; epi-Catechin; epi-Catechol; CCRIS 7097; EINECS 207-710-1; NSC 81161; Epicatechol, (-)-; CHEBI:90; 34PHS7TU43; PFTAWBLQPZVEMU-UKRRQHHQSA-N; (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; (-)-(2R:3R)-5,7,3',4'-Tetrahydroxyflavan-3-ol; AK105372; C15H14O6
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
methyl p-hydroxybenzoate
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Investigative | Compound Info | ||
| Synonyms |
methylparaben; nipagin
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
Rutin
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Investigative | Compound Info | ||
| Synonyms |
RUTIN; 153-18-4; rutoside; Phytomelin; Quercetin 3-rutinoside; Birutan; Eldrin; Rutin trihydrate; Myrticolorin; Venoruton; Bioflavonoid; Paliuroside; Tanrutin; Osyritrin; Rutine; Rutozyd; 3-Rutinosyl quercetin; 3-Rhamnoglucosylquercetin; Quercetin 3-O-rutinoside; Rutosido; Rutosidum; Rutinum; Globularicitrin; Quercetin-3-rutinoside; Rutabion; Violaquercitrin; Globulariacitrin; Melin; Rutinic acid; Birutan Forte; Birutin; Quercetin rhamnoglucosine; Quercetin-3beta-rutinoside; UNII-5G06TVY3R7; Oxyritin; Rutosid; Ilixanthin; Rutinion acid
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| Activity |
IC50 = 52200 nM
|
[3] | |||
| Compound Name |
QUERCITRIN
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Investigative | Compound Info | ||
| Synonyms |
quercitrin; 522-12-3; Quercetrin; Quercetin 3-rhamnoside; Quercitroside; Quercimelin; Thujin; Quercetin 3-L-rhamnoside; Quercitronic acid; Quercetin 3-O-rhamnoside; UNII-2Y8906LC5P; CHEBI:17558; Quercetin 3-O-alpha-L-rhamnoside; Quercetin-3-L-rhamnoside; 3,3',4',5,7-Pentahydroxyflavone-3-L-rhamnoside; Quercetin-3-rhamnoside; NSC9221; Quercetin, 3-(6-deoxy-alpha-L-mannopyranoside); 2Y8906LC5P; Mannopyranoside, quercetin-3 6-deoxy-, alpha-L-; Quercetin 3-O-alpha-rhamnopyranoside; Usaf cf-2; Quercetrin-3-O-rham
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
TILIROSIDE
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Investigative | Compound Info | ||
| Synonyms |
Tiliroside; 20316-62-5; Tribuloside; Trans-Tiliroside; UNII-15M04TXR9M; CHEMBL266564; 15M04TXR9M; CHEBI:80944; 22153-44-2; 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 6'-ester with 3-(beta-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; AC1NSZRJ; SCHEMBL23597; Tiliroside, analytical standard; MEGxp0_000169; MolPort-001-740-347; ZINC17654711; BDBM50241244; AKOS015896718; MCULE-6075035042; NCGC00163634-01; LS-123660; W1685; kaempferol 3-O-(6"-O-p-coumaroyl)-glucoside; C17140
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CATECHIN
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Investigative | Compound Info | ||
| Synonyms |
Cianidanol; (+)-catechin; 154-23-4; Catechuic acid; Cyanidanol; Catechinic acid; D-Catechin; Catergen; Cianidol; (+)-Cyanidanol; (+)-Cyanidan-3-ol; Biocatechin; (+)-Catechin Hydrate; D-(+)-Catechin; Dexcyanidanol; Catechin (flavan); Catechol (flavan); D-Catechol; (2R,3S)-Catechin; (2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol; Gambier; 3-Cyanidanol, (+)-; Cianidanolum; Catechu; Transepar; Katha; (2R,3S)-(+)-Catechin; Cutch (dye); (+)-Cianidanol; 3,3',4',5,7-Flavanpentol; KB-53; (+)-Cyanidanol-3; CCRIS 6855
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CIRSIMARIN
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Investigative | Compound Info | ||
| Synonyms |
Cirsimarin; Cirsitakaoside; 13020-19-4; CHEMBL517637; 2-(4-(beta-D-Glucopyranosyloxy)phenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2-(4-(beta-D-glucopyranosyloxy)phenyl)-5-hydroxy-6,7-dimethoxy-; AC1L4LVL; AC1Q6CLV; SCHEMBL2016369; MolPort-019-937-034; BDBM50250467; ZINC31459932; MCULE-1339456605; 4-(5-hydroxy-6,7-dimethoxy-4-oxo-4h-chromen-2-yl)phenyl; LS-39681
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
ISOSCOPOLETIN
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Investigative | Compound Info | ||
| Synonyms |
Isoscopoletin; 776-86-3; 6-Hydroxy-7-methoxycoumarin; 6-hydroxy-7-methoxy-2H-chromen-2-one; 7-Methoxyesculetin; Isoscopoletine; 6-hydroxy-7-methoxychromen-2-one; 2H-1-Benzopyran-2-one, 6-hydroxy-7-methoxy-; 6-hydroxy-7-methoxy-chromen-2-one; CHEMBL390320; CHEBI:81484; iso-scopoletin; 6-Hydroxy-7-methoxy-2-benzopyrone; EINECS 212-282-4; AC1L2CWN; Esculetin 7-methyl ether; Esculetin, 7-methyl ether; AC1Q4EZ0; 6-Hydroxy-7-methylcoumarin; SCHEMBL2790887; AC1Q69W0; CTK7A0381; DTXSID40228266; MolPort-003-927-047
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| Activity |
IC50 = 138000 nM
|
[4] | |||
| Compound Name |
Naringenin
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Investigative | Compound Info | ||
| Synonyms |
(S)-Naringenin; pelargidanon; Salipurol; naringetol; (2S)-Naringenin; salipurpol; Asahina; Naringenine; UNII-HN5425SBF2; NSC 11855; CCRIS 5839; NSC 34875; (-)-(2S)-Naringenin; CHEMBL9352; AI3-23355; HN5425SBF2; (-)-Naringenin; NARIGENIN; Flavanone, 4',5,7-trihydroxy- (8CI); 5,7,4'-Trihydroxyflavanone; SR-01000721771; Flavanone, 4',5,7-trihydroxy-; NSC-11855; EINECS 207-550-2; pelargidanon 1602; Spectrum_000247; Spectrum2_000325; Spectrum3_000567; Spectrum4_000124; Spectrum5_001423; 4',5,7-triOH-Flavone; 4',5,7-Trihydroxyflavanon; SCHEMBL20570; BSPBio_001954; KBioGR_000508; KBioSS_000727; MLS000574861; BIDD:ER0116; DivK1c_000118; SPECTRUM1500746; SPBio_000329; 4',5, 7-Trihydroxyflavanone; DTXSID1022392; BDBM23419; CTK8C4789; HMS500F20; KBio1_000118; KBio2_000727; KBio2_003295; KBio2_005863; KBio3_001454; NINDS_000118; (2S)-5,7,4'-trihydroxyflavone; AIDS001417; HMS2202M06; ZINC156701; (2S)-4',5,7-trihydroxyflavanone; HY-N0100; KS-000010IV; TNP00287; 2580AH; ANW-73132; CCG-38601; LMPK12140001; Phytochemistry 8: 127 (1969); s2394; AKOS016843490; CS-6421; DB03467; FS-4072; SB17305; SDCCGMLS-0066570.P001; (2S)-4',5,7-trihydroxyflavan-4-one; IDI1_000118; NCGC00016457-01; NCGC00016457-02; NCGC00016457-03; NCGC00017346-01; NCGC00163598-01; SMR000156272; FT-0617134; SW219329-1; C00509; Q418374; Q-100666; SR-01000721771-3; SR-01000721771-4; BRD-K08832567-001-02-4; BRD-K08832567-001-06-5
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
5-Hydroxy-2-(4-hydroxyphenyl)-6,7-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]chromen-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4089370; BDBM50253015
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| Activity |
IC50 = 50240 nM
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[5] | |||
| Compound Name |
Chembl4225751
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Investigative | Compound Info | ||
| Synonyms |
BDBM50460200
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| Activity |
IC50 = 50500 nM
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[6] | |||
| Compound Name |
Chembl4225688
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Investigative | Compound Info | ||
| Synonyms |
BDBM50460216
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| Activity |
IC50 = 52500 nM
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[6] | |||
| Compound Name |
3-[3-(Diethylamino)-propoxy]-6-hydroxyxanthone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761217; BDBM50340841
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| Activity |
IC50 = 53500 nM
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[7] | |||
| Compound Name |
3-[3-(Diethylamino)-propoxy]xanthone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761212; BDBM50340836
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| Activity |
IC50 = 56500 nM
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[7] | |||
| Compound Name |
(2R,4Ar,6aR,6aR,6bR,8aR,9S,10S,12aR,14aR,14bS)-9-[[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-2,10-dihydroxy-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14,14a,14b-hexadecahydropicene-4a-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4080985; BDBM50253034
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| Activity |
IC50 = 56680 nM
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[5] | |||
| Compound Name |
(2R,4Ar,6aR,6aR,6bR,8aR,9S,10S,12aR,14aR,14bS)-9-[[(2R,3R,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxymethyl]-2,10-dihydroxy-2,6a,6b,9,12a-pentamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14,14a,14b-hexadecahydropicene-4a-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4097526; BDBM50253024
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| Activity |
IC50 = 57420 nM
|
[5] | |||
| Compound Name |
Chembl4227343
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Investigative | Compound Info | ||
| Synonyms |
BDBM50460205
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| Activity |
IC50 = 58100 nM
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[6] | |||
| Compound Name |
Methyl (2R)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]-3-(1H-indol-3-yl)propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4094442; BDBM50233819
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
(2S)-2-[[(E)-3-[2-(3,4-Dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4062375; BDBM50233814
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
(2S)-2-[[(E)-3-[2-(3,4-Dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100541; BDBM50233753
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
Methyl (2R)-3-(3,4-dihydroxyphenyl)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065801; BDBM50233751
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
(2S)-2-[[(E)-3-[2-(3,4-Dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]-3-phenylpropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4090366; BDBM50233813
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| Activity |
IC50 ~ 60000 nM
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[8] | |||
| Compound Name |
(2R)-3-(3,4-Dihydroxyphenyl)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4082526; BDBM50233812
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
Methyl (2S)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4071668; BDBM50233804
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| Activity |
IC50 ~ 60000 nM
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[8] | |||
| Compound Name |
Methyl (2S)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]-3-(4-hydroxyphenyl)propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066956; BDBM50233752
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
Methyl (2S)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]-3-phenylpropanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4092465; BDBM50233818
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
Methyl (2S)-3-(3,4-dihydroxyphenyl)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4093409; BDBM50233755
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
(2R)-2-[[(E)-3-[2-(3,4-Dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]-3-(1H-indol-3-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098091; BDBM50233822
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
(2S)-3-(3,4-Dihydroxyphenyl)-2-[[(E)-3-[2-(3,4-dihydroxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoyl]amino]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4083271; BDBM50233821
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| Activity |
IC50 ~ 60000 nM
|
[8] | |||
| Compound Name |
[(2R,3S,4S,5R,6R)-6-[3-(3,4-Dihydroxyphenyl)propoxy]-3,4,5-trihydroxyoxan-2-yl]methyl 4-hydroxy-3-methoxybenzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4081495; BDBM50253016
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| Activity |
IC50 = 61100 nM
|
[5] | |||
| Compound Name |
3-[3-(Cyclopropylamino)-propoxy]-6-hydroxyxanthone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761215; BDBM50340839
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| Activity |
IC50 = 63000 nM
|
[7] | |||
| Compound Name |
Chembl4229154
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Investigative | Compound Info | ||
| Synonyms |
BDBM50460208
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| Activity |
IC50 = 64300 nM
|
[6] | |||
| Compound Name |
3-[3-(Pyrrolidin-1-yl)-propoxy]xanthone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761209; BDBM50340833
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| Activity |
IC50 = 65500 nM
|
[7] | |||
| Compound Name |
1,3,7,8-Tetrahydro-6H-[1,3]thiazino[3,2-a]purine-2,10-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL83072; BDBM50051715; 2-Hydroxy-7,8-dihydro-3H,6H-5-thia-1,3,4,8a-tetraaza-cyclopenta[b]naphthalen-9-one
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| Activity |
Ki = 66800 nM
|
[9] | |||
| Compound Name |
3-Hydroxy-6-[3-(pyrrolidin-1-yl)-propoxy]xanthone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761214; BDBM50340838
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| Activity |
IC50 = 68800 nM
|
[7] | |||
| Compound Name |
3-[3-(Cyclohexylamino)-propoxy]-6-hydroxyxanthone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761216; BDBM50340840
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| Activity |
IC50 = 72900 nM
|
[7] | |||
| Compound Name |
8-Hydroxy-2-phenylmethanesulfonyl-1,9-dihydro-purin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL314168; BDBM50051733; 2-Benzylsulfonyl-8-hydroxy-1,9-dihydro-6H-purin-6-one
Click to Show/Hide
|
||||
| Activity |
Ki = 77840 nM
|
[9] | |||
| Compound Name |
(-)-Specioside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL516849; BDBM50250503
Click to Show/Hide
|
||||
| Activity |
IC50 = 79880 nM
|
[10] | |||
| Compound Name |
N-(4''-Carboxyphenyl)-1H-4-aminopyrazolo[3,4-d]pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL500751; BDBM50242766
Click to Show/Hide
|
||||
| Activity |
IC50 = 80970 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-6-[3-(piperidin-1-yl)-propoxy]xanthone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761213; BDBM50340837
Click to Show/Hide
|
||||
| Activity |
IC50 = 82300 nM
|
[7] | |||
| Compound Name |
[(2R,3S,4S,5R,6R)-6-[1,3-Dihydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl 4-hydroxy-3,5-dimethoxybenzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091776; BDBM50253017
Click to Show/Hide
|
||||
| Activity |
IC50 = 86220 nM
|
[5] | |||
| Compound Name |
5-Nitrobenzimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-Nitrobenzimidazole; 5-nitro-1H-benzo[d]imidazole; 5-Nitro-1H-benzimidazole; 6-Nitro-1H-benzimidazole; 1H-Benzimidazole, 5-nitro-; 1H-Benzimidazole, 6-nitro-; 6-Nitro-benzimidazole; 5(6)-Nitrobenzimidazole; Benzimidazole, 5-nitro-; Benzimidazole, 6-nitro-; NCI-C01912; UNII-A7V95AYT2T; 5-Nitro-1H-benzoimidazole; MFCD00005604; 5-nitro-1H-1,3-benzodiazole; A7V95AYT2T; MLS002637666; CHEMBL164921; 1H-BENZIMIDAZOLE,5-NITRO-; DSSTox_CID_965; DSSTox_RID_75893; DSSTox_GSID_20965; WLN: T56 BM DNJ HNW; CCRIS 442; HSDB 2864; NSC 3068; EINECS 202-341-2; NSC 58858; 6-Nitro-1H-benzo[d]imidazole; AI3-52609; 6-nitro-1H-1,3-benzodiazole; 5-nitrobenzoimidazol; 5-nitrobenzoimidazole; 5-nitro-benzimidazole; PubChem7543; ACMC-209rse; 5(6)-nitro-benzimidazole; Benzimidazole, 5(or 6)-nitro- (6CI,7CI); 6-Nitro-1H-benzoimidazole; 1h-benzimidazole,6-nitro-; Oprea1_525754; Oprea1_664147; SCHEMBL271340; 5-nitro-1H-1,3-benzimidazole; DTXSID8020965; CTK2I9581; CTK3J0760; KS-00000WQW; Benzimidazole, 5-nitro- (8CI); NSC3068; HMS3079A05; BCP26862; NSC-3068; NSC58858; ZINC4693007; Tox21_201684; Tox21_302828; ANW-40284; ANW-46429; BBL007924; BDBM50208881; NSC-58858; SBB046252; STK299272; AKOS000275609; AKOS003790796; AKOS015970456; CS-W010848; MCULE-7385886412; NCGC00091868-01; NCGC00091868-02; NCGC00091868-03; NCGC00091868-04; NCGC00091868-05; NCGC00091868-06; NCGC00256398-01; NCGC00259233-01; AC-11286; AK-86195; AM808099; AS-46775; SC-07411; SMR001305771; SY003312; DB-057506; BB 0219456; EU-0067493; FT-0620702; N0152; ST45061660; T8309; V2292; L-1302; 040B457; 2-[(4,6-Dimethoxypyrimidin-2-yl)thio]benzoicacid; AE-641/30196001; SR-01000394488; SR-01000394488-1; W-100194; Q27273738; F0020-1984
Click to Show/Hide
|
||||
| Activity |
IC50 = 86840 nM
|
[2] | |||
| Compound Name |
3-Hydroxy-6-[3-(piperazino)-propoxy]xanthone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761218; BDBM50340842
Click to Show/Hide
|
||||
| Activity |
IC50 = 91900 nM
|
[7] | |||
| Compound Name |
2-Phenyl-7,8-dihydro-3H,6H-9-thia-1,3,4,5a-tetraaza-cyclopenta[a]naphthalen-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL82848; BDBM50051728; 2-Phenyl-7,8-dihydro-6H-9-thia-1,3,4,5a-tetraaza-5aH-benz[e]inden-5(3H)-one
Click to Show/Hide
|
||||
| Activity |
Ki = 93000 nM
|
[9] | |||
| Compound Name |
4-Hydroxy-3-methoxycinnamaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Coniferaldehyde; Coniferyl aldehyde; coniferylaldehyde; Ferulyl aldehyde; 3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde; 3-(4-Hydroxy-3-methoxyphenyl)prop-2-enal; UNII-06TPT01AD5; Ferulaldehyde; (E)-3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde; (2e)-3-(4-Hydroxy-3-Methoxyphenyl)prop-2-Enal; 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-; 3-Methoxy-4-hydroxycinnamaldehyde; Cinnamaldehyde, 4-hydroxy-3-methoxy-; 06TPT01AD5; CHEMBL242529; (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal; 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl), (E)-; Q63390505; p-Coniferaldehyde; (E)-Ferulaldehyde; trans-Coniferaldehyde; 3-(4-Hydroxy-3-methoxyphenyl)-2-propenal; Ferulic Aldehyde; Coniferylic aldehyde; (E)-coniferaldehyde; Trans-Coniferylaldehyde; 2-Methoxy-4-(3-oxo-1-propenyl)phenol; 4-Hydroxy-3-methoxy-trans-cinnamaldehyde; bmse000422; bmse000601; bmse010076; SCHEMBL167835; DTXSID10174685; 4-Hydroxy3-Methoxy Cinnamaldehyde; HY-N2535; STR05037; ZINC1529491; 4-hydroxy-3-methoxycinnamic aldehyde; 6308AB; BDBM50211193; MFCD00075811; s9221; STL479559; 3-BIPHENYL-3-AMINO-ACETICACID; AKOS015916118; CCG-266411; 4-Hydroxy-3-methoxycinnamaldehyde, 98%; CS-0022807; W2108; C02666; (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enal; 5DF06912-B0DD-4C76-B493-29D29F746430
Click to Show/Hide
|
||||
| Activity |
Ki = 93880 nM
|
[12] | |||
| Compound Name |
Hexadecanoic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92193; BDBM50131452; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-(palmitoyloxy)chroman-7,8-diol
Click to Show/Hide
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||||
| Activity |
IC50 = 94700 nM
|
[13] | |||
| Compound Name |
Chembl4175403
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BDBM50278951
Click to Show/Hide
|
||||
| Activity |
IC50 = 95400 nM
|
[14] | |||
| Compound Name |
(2R,3R)-2-(3,4-Dihydroxyphenyl)-3-hydroxy-5,6,7-trimethoxy-2,3-dihydrochromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467247; BDBM50258903
Click to Show/Hide
|
||||
| Activity |
IC50 = 96700 nM
|
[15] | |||
| Compound Name |
Yemuoside YM10
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3890430; Yemuoside YM(10); SCHEMBL17187835; HY-N0307; BDBM50253018; CS-0008805; Q-100073
Click to Show/Hide
|
||||
| Activity |
IC50 = 97300 nM
|
[5] | |||
| Compound Name |
4-[4-Cyano-5-[[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]amino]pyrazol-1-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL518487; BDBM50242779
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
2-[7-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-5-yl]oxyacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594385; BDBM50098347
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Trpyrth
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315969; DTXSID80163369; BDBM50051736; 7H-8,9-Dihydro-(1,2,3)triazolo(4',5'-4,5)pyrimido(6,1-b)(1,3)thiazine-5(1H)-one; 9H-7,8-Dihydro-(1,2,3)triazolo(4',5'-4,5)pyrimido(6,1-b)(1,3)thiazine-5(3H)-one; 13-thia-3,4,5,7,9-pentazatricyclo[7.4.0.02,6]trideca-1,4,6-trien-8-one; 7,8-Dihydro-3H,6H-9-thia-1,2,3,4,5a-pentaaza-cyclopenta[a]naphthalen-5-one; 7H-1,2,3-Triazolo(4',5':4,5)pyrimido(6,1-b)(1,3)thiazin-5(1H)-one, 8,9-dihydro-
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
2-[5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594373; BDBM50098341
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
7-O-[alpha-L-Rhamnosyl-(1->2)-beta-D-glucosyl]chrysoeriol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL447820; Chrysoeriol 7-O-Neohesperidosyl; Chrysoeriol 7-O-Neohesperidoside; Chrysoeriol 7-neohesperidoside; chrysoeriol 7-O-rhamnosylglucoside; BDBM50250469; ZINC49841244; 7-neohesperidosyl-3''-methylluteolin; MCULE-3723645047; Q27145374
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Nobiletin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hexamethoxyflavone; 3',4',5,6,7,8-Hexamethoxyflavone; 5,6,7,8,3',4'-Hexamethoxyflavone; UNII-D65ILJ7WLY; 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one; 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one; NSC-76751; D65ILJ7WLY; 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one; CHEMBL76447; Nobiletin (Hexamethoxyflavone); NSC76751; MFCD03273560; Flavone, 5,6,7,8,3',4'-hexamethoxy; 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-; SMR000156231; CCRIS 9012; NSC 76751; CPD000156231; Nobiletin, >=97%; Spectrum2_001697; Spectrum3_000921; Spectrum4_001020; KBioGR_001519; MLS000574877; MLS000759462; MLS000877030; MLS001424129; Nobiletin, analytical standard; SCHEMBL244029; SPECTRUM1505268; SPBio_001654; MEGxp0_000930; ACon1_000921; CTK4J0325; KBio3_001922; DTXSID30197275; 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-chromen-4-one; HMS2051D09; HMS2234A09; HMS3373C14; HMS3393D09; HMS3651G20; HY-N0155; ZINC1531669; 3'4'5,6,7,8-Hexamethoxyflavone; 3,4,5,6,7,8-Hexamethoxyflavone; ANW-42631; BDBM50338976; CCG-38781; CN0043; LMPK12111468; NSC618903; STL565829; 4H-1-Benzopyran-4-one,2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-; AKOS015965334; NOBILETIN, 20% (Technical Grade); AC-1023; CS-5518; MCULE-1015144950; NC00186; NSC-618903; SDCCGMLS-0066776.P001; NCGC00095703-01; NCGC00095703-02; NCGC00169228-01; 5,6,7,8,3'',4''-hexamethoxyflavone; AK168175; AS-17452; NCI60_041691; SC-25982; DB-050181; FT-0686667; N0871; N1311; S2333; SW197566-2; V0181; C10112; SR-01000712262; Q-100511; Q2402963; SR-01000712262-5; BRD-K06753942-001-02-0; 2-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetramethoxy-chromen-4-one; 4H-1-Benzopyran-4-one,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-; 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one, 9CI; 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy- (9CI)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
7-Methyl-3,6,7,8-tetrahydro-1H-[1,3]thiazino[3,2-a]purine-2,10-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315417; BDBM50051741; 2-Hydroxy-7-methyl-7,8-dihydro-3H,6H-5-thia-1,3,4,8a-tetraaza-cyclopenta[b]naphthalen-9-one
Click to Show/Hide
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||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
Chembl4224890
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50460207
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
4-[5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxybutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594374; BDBM50098340
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
5-Amino-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL501787; 5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile; 5-Amino-1-(4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile; SCHEMBL10555775; 5-amino-1-[4-(trifluoromethyl)phenyl]pyrazole-4-carbonitrile; BDBM50242761; MFCD11922351; ZINC32107406; AKOS017565682; AS-43063; SC-56361; 5-Amino-1-(4-trifluoromethyl-phenyl)-1H-pyrazole-4; Z2492774589; 1-[4-(Trifluoromethyl)phenyl]-5-amino-1H-pyrazole-4-carbonitrile; 5-Amino-1-(4''-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
Chembl4225990
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50460209
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
Chembl4228302
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50460215
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
7-[5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyheptanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594377; BDBM50098337
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Tangeretin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Tangeritin; Ponkanetin; Pentamethoxyflavone; 4',5,6,7,8-Pentamethoxyflavone; 5,6,7,8,4'-Pentamethoxyflavone; Tangeretin (6CI); 4H-1-Benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-; 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one; UNII-I4TLA1DLX6; NSC 53909; 5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4-benzopyrone; 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one; 4',5,6,7,8-pentamethoxy-flavone; I4TLA1DLX6; CHEMBL73930; MLS002667634; 4H-1-Benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(p-methoxyphenyl)-; 5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; NSC53909; Flavone, 4',5,6,7,8-pentamethoxy- (7CI,8CI); MFCD00017438; NSC-53909; Flavone, 5,6,7,8,4'-pentamethoxy; Tangeritin; NSC53909; NSC618905; EINECS 207-570-1; BRN 0351695; AI3-23869; Tangeretin (Tangeritin); 2-(4-Methoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one; Spectrum2_001698; Spectrum3_000920; Spectrum4_001019; SCHEMBL19740; KBioGR_001517; 5-18-05-00491 (Beilstein Handbook Reference); SPECTRUM1505269; SPBio_001656; Tangeretin, analytical standard; MEGxp0_001011; Tangeretin, >=95% (HPLC); ACon1_001263; KBio3_001900; DTXSID30197417; Flavone,5,6,7,8-pentamethoxy-; HMS3651A22; HY-N0133; ZINC1531699; 4'',5,6,7,8-pentamethoxyflavone; 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-5,6,7,8-tetramethoxy-; 5,6,7,8,4''-Pentamethoxyflavone; BDBM50209218; CCG-38782; CT0015; LMPK12111443; NSC618905; s2363; AKOS015895209; AC-1699; CS-5484; MCULE-1727108016; NSC 618905; NSC-618905; SDCCGMLS-0066766.P001; Flavone, 4',5,6,7,8-pentamethoxy-; NCGC00095850-01; NCGC00095850-02; NCGC00169520-01; AK168079; AS-11637; NCI60_004330; SC-46059; SMR001557394; ST097546; AB0010469; FT-0632194; N2077; SW219232-1; C10190; K-9174; 481T538; SR-05000002625; CU-01000013437-2; Q-100525; Q1748737; SR-05000002625-1; BRD-K25186396-001-02-1; BRD-K25186396-001-04-7; 4H-1-Benzopyran-4-one,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-; 4H-1-Benzopyran-4-one,6,7,8-tetramethoxy-2-(p-methoxyphenyl)-; 4H-1-Benzopyran-4-one, 5,6,7,8-tetra-methoxy-2-(4-methoxyphenyl)-; 5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 9CI
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4S)-3,4-Dihydroxy-4-[(4-hydroxy-3-methoxybenzoyl)oxymethyl]oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-methoxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4099514; BDBM50253025; MCULE-4442379644; NCGC00384724-01
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
8-[7-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-5-yl]oxyoctanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594390; BDBM50098342
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-Butylthio-5-formylamino-6-aminopyrimidin-4(3H)-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL314120; BDBM50051720; N-(4-Amino-2-butylsulfanyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
5-Amino-1-(4-nitrophenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
5-amino-1-(4-nitrophenyl)pyrazole-4-carbonitrile; CHEMBL460379; 5-amino-1-{4-nitrophenyl}-1H-pyrazole-4-carbonitrile; NSC1397; PubChem14490; SCHEMBL5860236; CTK1H4029; DTXSID70277262; ZINC336283; NSC-1397; BDBM50242760; MFCD00052885; SBB063799; STL582241; AKOS000260137; ACN-000207; MCULE-4668689654; VP20118; KS-00000G33; AK124009; SC-62500; DB-052434; FT-0635659; EN300-31474; M-1851; 3Y-0943; AN-970/40920413; J-516642; Z55148820; 1-(4-Nitrophenyl)-5-amino-1H-pyrazole-4-carbonitrile; 5-AMINO-1-(P-NITROPHENYL)PYRAZOLE-4-CARBONITRILE; 5-Amino-1-(4''-nitrophenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
6-[7-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-5-yl]oxyhexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594388; SCHEMBL19236007; BDBM50098344
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-(6-Oxo-4-phenyl-1H-pyrimidin-2-yl)methanesulfonamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3127145; BDBM50449129; MCULE-1404934228
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
7-Methyl-2-thioxo-3,6,7,8-tetrahydro-1H-[1,3]thiazino[3,2-a]purin-10-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC658169; CHEMBL85314; BDBM50051723; NSC-658169; NCI60_020328; 7-Methyl-2-thioxo-2,3,7,8-tetrahydro-6H-[1,3]thiazino[3,2-a]purin-10(1H)-one; 2-Mercapto-7-methyl-7,8-dihydro-3H,6H-5-thia-1,3,4,8a-tetraaza-cyclopenta[b]naphthalen-9-one
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[9] | |||
| Compound Name |
5-Amino-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Amino-1-(p-tolyl)-1H-pyrazole-4-carbonitrile; 5-Amino-1-p-tolyl-1H-pyrazole-4-carbonitrile; 5-amino-1-(4-methylphenyl)pyrazole-4-carbonitrile; CHEMBL443354; 1H-Pyrazole-4-carbonitrile,5-amino-1-(4-methylphenyl)-; PubChem14487; ACMC-20a3sh; Maybridge1_001728; MLS000833729; SCHEMBL1456317; CTK4A2288; HMS546G12; ZINC93115; DTXSID90384164; HMS2809M05; ALBB-030579; KS-00000G8F; ANW-55839; BDBM50242691; MFCD00052944; SBB092307; STL507855; AKOS000260140; ACN-000203; MCULE-2419748518; VP20117; AK-56367; SC-62503; SMR000457250; DB-040474; A1870; FT-0642537; K-0391; A800776; 11X-0946; 5-amino-1-(4-methylphenyl)-4-pyrazolecarbonitrile; 5-azanyl-1-(4-methylphenyl)pyrazole-4-carbonitrile; J-516643; 1-(4-Methylphenyl)-5-amino-1H-pyrazole-4-carbonitrile; F2135-0877
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
5-[7-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-5-yl]oxypentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594387; BDBM50098345
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-Hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Flavonol; 3-Hydroxy-2-phenyl-4H-chromen-4-one; Flavon-3-ol; 3-Hydroxy-2-phenylchromone; 4H-1-Benzopyran-4-one, 3-hydroxy-2-phenyl-; FLAVONE, 3-HYDROXY-; 3-hydroxy-2-phenylchromen-4-one; UNII-ZTG9LSS5QH; MFCD00006832; ZTG9LSS5QH; NSC57653; CHEMBL294009; 3-hydroxy-2-phenyl-4H-1-benzopyran-4-one; NSC-57653; F0013-0884; flavonols; FLAVONE,3-HYDROXY-; NSC58585; SR-01000401360; EINECS 209-416-9; NSC 57653; NSC 58585; 3-hydroxyflavon; HSDB 7572; 3-hydroxy-2-phenyl-chromen-4-one; Spectrum_000328; SpecPlus_000831; Spectrum2_001392; Spectrum3_001432; Spectrum4_001845; Spectrum5_000350; ACMC-209m0e; Oprea1_038914; Oprea1_692205; SCHEMBL20246; 3-Hydroxyflavone, >=98%; 4-Hydroxy-3-oxylatoflavylium; BSPBio_003164; KBioGR_002250; KBioSS_000808; MLS002207277; BIDD:ER0553; DivK1c_006927; SPECTRUM1501012; SPBio_001404; MEGxp0_001695; DTXSID4060365; ACon1_000167; CTK3J2720; KBio1_001871; KBio2_000808; KBio2_003376; KBio2_005944; KBio3_002384; ZINC57675; HMS3740M15; KUC106685N; KS-00000VN5; WLN: T66 BO EVJ CR& DQ; ANW-32796; BDBM50187668; CCG-38858; NCI-57653; s4790; SBB000767; AKOS000599906; MCULE-8535739842; SDCCGMLS-0066736.P001; NCGC00095653-01; NCGC00095653-02; NCGC00095653-03; 3-Hydroxy-2-phenyl-4H-chromen-4-one #; AK163706; AS-19638; SMR000112317; ST086622; SY048803; KSC-11-207-16; DB-053103; HY-107825; CS-0030701; EU-0001678; FT-0615841; Y2009; VU0053575-3; C01495; H-5000; 3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one, 9CI; Q5919049; SR-01000401360-1; SR-01000401360-2; BRD-K55150756-001-05-7; B48D3495-6D21-4742-8A87-D3DE07DC9554
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-ethyl-1,5-dihydro-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL84620; SCHEMBL3700367; BDBM50051735; ZINC26567898; AKOS015902174; 6-ethyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Ethyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one; 4h-pyrazolo[3,4-d]pyrimidin-4-one,6-ethyl-1,5-dihydro-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
5-Amino-1-(4-cyanophenyl)pyrazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL448272; SCHEMBL3876365; BDBM50242704; 5-Amino-1-(4''-cyanophenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
6-Propyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL316254; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-6-propyl-; BDBM50051730; ZINC26569699; 6-propyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Chembl4226441
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50460210
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
2-Hexylthio-5-formylamino-6-aminopyrimidin-4(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL86132; BDBM50051744; N-(4-Amino-2-hexylsulfanyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Apigenin-4''-O-(6''''-O-p-coumaroyl)-beta-D-glucopyranoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL503232; BDBM50269379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
6-Xylosyl-8-glucosylapigenin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL455678; BDBM50250466
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-Amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-amino-1-(4-methoxyphenyl)pyrazole-4-carbonitrile; CHEMBL452145; 5-amino-1-(4-methoxy-phenyl)-1h-pyrazole-4-carbonitrile; SCHEMBL3300932; CTK4B0034; KS-00001NEE; 1H-Pyrazole-4-carbonitrile, 5-amino-1-(4-methoxyphenyl)-; DTXSID60377184; ZINC3883869; 2755AA; ANW-74469; BBL034731; BDBM50242692; MFCD00128343; SBB024026; STK351072; AKOS000313695; MCULE-5805421386; SC-56364; ST45119066; 3Y-0920; 1-(4-methoxyphenyl)-5-amino-4-pyrazolecarbonitrile; J-516640; 5-Amino-1-(4-methoxy-phenyl)-1H-pyrazole-4-carboni; 1-(4-Methoxyphenyl)-5-amino-1H-pyrazole-4-carbonitrile; 5-Amino-1-(4''-methoxyphenyl)-1H-pyrazole-4-carbonitrile; 5-amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carbonitrile, AldrichCPR; 5-Amino-1-(4-methoxy-phenyl)-1H-pyrazole-4-carbonitrile, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
4-[7-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-5-yl]oxybutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594386; BDBM50098346
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
6-[5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyhexanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594376; BDBM50098338
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-butyl-1,5-dihydro-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL84772; BDBM50051729; ZINC26570343; 6-butyl-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Butyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6a,6b,9,9,12a-pentamethyl-2-methylidene-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4067652; BDBM50253026
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
5-[5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxypentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594375; BDBM50098339
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-amino-1-(4-chlorophenyl)pyrazole-4-carbonitrile; CHEMBL460460; MFCD00052031; Maybridge1_001852; ACMC-1B1LD; SCHEMBL1143771; CTK3J7099; HMS546M04; ZINC93021; 1H-pyrazole-4-carbonitrile, 5-amino-1-(4-chlorophenyl)-; DTXSID00348616; HMS3604K21; ALBB-031077; KS-00000F0L; BDBM50242762; SBB028434; STL444078; AKOS000260327; ACN-000199; DB07291; DS-6686; MCULE-6824406288; QC-4502; SDCCGMLS-0065863.P001; AK139441; SC-56362; FT-0619953; Y9289; C-1084; 5-Amino-1-(4-chlorophenyl)-4-cyano-1H-pyrazole; J-516639; 5-Amino-1-(4-chloro-phenyl)-1H-pyrazole-4-carbonit; Q27096517; 1-(4-Chlorophenyl)-5-amino-1H-pyrazole-4-carbonitrile; 5-Amino-1-(4''-chlorophenyl)-1H-pyrazole-4-carbonitrile; 5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carbonitrile, 97%
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-(6-Oxo-3,7-dihydropurin-2-yl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL85062; Butanamide, N-(6,9-dihydro-6-oxo-1H-purin-2-yl)-; SCHEMBL8843889; BDBM50051721; N-(6-Oxo-6,9-dihydro-1H-purin-2-yl)-butyramide; N-[(6-Oxo-6,9-dihydro-1H-purin)-2-yl]butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-Amino-3-methyl-6-phenyl-4-pyrimidinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3127146; SCHEMBL4493177; BDBM50449128; 2-amino-3-methyl-6-phenylpyrimidin-4-one; 2-amino-3-N-methyl-6-phenyl-4-pyrimidinone; 2-Amino-3-methyl-6-phenyl-3H-pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
6-Pentyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL82756; SCHEMBL16712554; BDBM50051745; ZINC26507739; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-6-pentyl-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-(4-Hydroxyphenyl)-5,7-dihydroxy-6,8-bis(beta-D-glucopyranosyloxy)-4H-1-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL538921
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Epigallocatechin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(-)-Epigallocatechin; Epigallocatechol; epi-Gallocatechin; L-Epigallocatechin; Antiscurvy factor C2; (-)-Epigallocatechol; l-Epigallocatechol; Gallocatechol; (-)-3,3',4',5,5',7-Flavanhexol; 3,3',4',5,5',7-Flavanhexol; 2,3-cis-epigallocatechin; UNII-7Z197MG6QL; (2R,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; CHEMBL47386; 7Z197MG6QL; (-)-cis-3,3',4',5,5',7-Hexahydroxyflavane; (2R,3R)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol; MFCD00075939; 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL; (-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol; (2R,3R)-2-(3,4,5-trihydroxyphenyl)chromane-3,5,7-triol; Galloepicatechin; Factor C2 (antiscurvy); Antiscurvy factor C(sub 2); CCRIS 5441; (-)-epi-Gallocatechin; (-)-Epigallocatechin(EGC); C15H14O7; Teacatechin II; NSC674039; 1-epi-3',4',5,5',7-Pentahydroxy-3-Flavan; (-) epigallocatechin; (-)-3,5,7,3',4',5'-Hexahydroxylflavan; epigallocatechin (egc); Spectrum_000806; (-)-Epigallocatechin,; SpecPlus_000269; GC; (-)-gallocatechin; Spectrum2_000703; Spectrum3_000248; Spectrum4_000950; Spectrum5_000889; SCHEMBL19553; BSPBio_001636; KBioGR_001540; KBioSS_001286; SPECTRUM205113; DivK1c_006365; SPBio_000885; BCBcMAP01_000207; KBio1_001309; KBio2_001286; KBio2_003854; KBio2_006422; KBio3_001136; DTXSID40891550; HY-N0225; KS-00000L8I; ZINC3870336; (-)-Epigallocatechin from green tea; BDBM50187665; CCG-38353; LMPK12020004; s3922; AKOS015965244; CS-3762; DB03823; DS-5807; NSC-674039; SDCCGMLS-0066479.P001; SMP1_000114; NCGC00179131-01; NCGC00179131-02; (-)-Epigallocatechin, analytical standard; NCI60_026204; SC-20992; (3,3',4',5,5',7-Hexahydroxyflavan); (-)-Epigallocatechin, 95%, from green tea; E1084; N2414; A12045; C12136; (-)-cis-3,3',4',5,5',7-Hexahydroxyflavan; 970E741; SR-05000002564; Q-200003; Q3044728; SR-05000002564-1; Q51617505; (-)-Epigallocatechin, >=95% (HPLC), from green tea; (2R,3R)-2-(3,4,5-trihydroxyphenyl)chroman-3,5,7-triol; C24E9F59-8F06-44E2-B2DE-FF132A8774F3; Epigallocatechin, primary pharmaceutical reference standard; UNII-T432289GYZ component XMOCLSLCDHWDHP-IUODEOHRSA-N; (-)cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 2H-1-Benzopyran-3,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-, (2R-cis)-
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
7-[7-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-5-yl]oxyheptanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594389; BDBM50098343
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
8-[5-Hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoctanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3594378; BDBM50098336
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
[(2S,3R,4R,5S,6R)-6-[4-(5,7-Dihydroxy-4-oxochromen-2-yl)phenoxy]-3,4-dihydroxy-5-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL454228; BDBM50269380; apigenin-4''-O-(2'''',6''''-di-O-p-coumaroyl)-beta-D-glucopyranoside
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
2-Pentylthio-5-formylamino-6-aminopyrimidin-4(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL83516; BDBM50051724; N-(4-Amino-6-oxo-2-pentylsulfanyl-1,6-dihydro-pyrimidin-5-yl)-formamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Hypolaetin-8-glucoside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-82IW02I7T8; CHEMBL4097078; 82IW02I7T8; Hypolaetin 8-glucoside; SCHEMBL21752781; DTXSID70182044; BDBM50253014; Q27269334
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-Acetamido-6-phenyl-4-pyrimidinone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3127144; CTK5A0342; DTXSID40479993; BDBM50449130; ZINC14981986; 2-acetylamino-6-phenyl-3H-pyrimidin-4-one; DB-017496; FT-0742203; N-(6-Oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)acetamide; Acetamide,N-(1,6-dihydro-6-oxo-4-phenyl-2-pyrimidinyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-6-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-8-[(3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxychromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL504233; BDBM50250465
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Isoolivil
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Cycloolivil; (+)-Cycloolivil; CHEMBL516536; rel-Isoolivil; MEGxp0_001281; SCHEMBL2902615; Cycloolivil, analytical standard; ACon1_001444; HY-N3670; ZINC1668769; 9177AF; BDBM50250506; AKOS032949006; MCULE-1091569412; Cycloolivil, >=95% (LC/MS-ELSD); CS-0024029; BRD-K14461684-001-01-4
Click to Show/Hide
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||||
| Activity |
IC50 = 101380 nM
|
[10] | |||
| Compound Name |
Tetradecanoic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419512; BDBM50131446; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-(myristoyloxy)chroman-7,8-diol
Click to Show/Hide
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||||
| Activity |
IC50 = 102000 nM
|
[13] | |||
| Compound Name |
3-[3-(Piperazino)-propoxy]xanthone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1761211; BDBM50340835
Click to Show/Hide
|
||||
| Activity |
IC50 = 108700 nM
|
[7] | |||
| Compound Name |
7'-Hydroxydivanillyltetrahydrofuran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517783; 7''-hydroxydivanillyltetrahydrofuran; BDBM50250507; 2-Methoxy-4-[[(3S,4R)-4-[alpha,4-dihydroxy-3-methoxybenzyl]tetrahydrofuran]-3-ylmethyl]phenol
Click to Show/Hide
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||||
| Activity |
IC50 = 110880 nM
|
[10] | |||
| Compound Name |
Decanoic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL94460; BDBM50131450; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-(decanoyloxy)chroman-7,8-diol
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| Activity |
IC50 = 112000 nM
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[13] | |||
| Compound Name |
(2S,3R,4R,5R,6R)-2-Methyl-6-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenoxy]oxan-2-yl]methoxy]oxane-3,4,5-triol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL477753; BDBM50259882; trans-4'',5-dihydroxy-3-methoxystilbene-5-O-[alpha-L-rhamnopyranosyl-(1->6)]-beta-D-glucopyranoside
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| Activity |
IC50 = 129000 nM
|
[19] | |||
| Compound Name |
Hexanoic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL327396; BDBM50131456; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-(hexanoyloxy)chroman-7,8-diol
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| Activity |
IC50 = 129000 nM
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[13] | |||
| Compound Name |
2-Sulfanylidene-3,6,7,8-tetrahydro-1H-[1,3]thiazino[3,2-a]purin-10-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL84718; BDBM50051717; 2-Mercapto-7,8-dihydro-3H,6H-5-thia-1,3,4,8a-tetraaza-cyclopenta[b]naphthalen-9-one
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| Activity |
Ki = 131000 nM
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[9] | |||
| Compound Name |
2''-Ethoxy-5''-methoxy-2-(5-methylthienyl)chalcone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL476787; BDBM50263222
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| Activity |
IC50 = 131000 nM
|
[20] | |||
| Compound Name |
3-Hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
3-hydroxy-2H-chromen-2-one; 3-Hydroxy-2-benzopyrone; 3-hydroxychromen-2-one; 3 Hydroxycoumarin; hydroxycoumarin; 3-Hydroxy-2H-1-benzopyran-2-one; UNII-RQX0CMD9PN; 3-Hydroxy-chromen-2-one; RQX0CMD9PN; CHEMBL150372; 2H-1-Benzopyran-2-one, hydroxy-; EINECS 213-355-3; NSC 74691; 2H-1-Benzopyran-2-one, 3-hydroxy-; BRN 0128032; COUMARIN, 3-HYDROXY-; 3-hydroxy-coumarin; 3-hydroxychromenone; NSC74691; Spectrum_000476; SpecPlus_000860; Spectrum2_000805; Spectrum3_001267; Spectrum4_001576; Spectrum5_000232; 2H-1-Benzopyran-2-one, 3-hydroxy- (9CI); hydroxy-2H-chromen-2-one; SCHEMBL76090; BSPBio_002834; KBioGR_002132; KBioSS_000956; SPECTRUM211538; 5-18-01-00376 (Beilstein Handbook Reference); DivK1c_006956; SPBio_000669; CTK1D2829; KBio1_001900; KBio2_000956; KBio2_003524; KBio2_006092; KBio3_002334; DTXSID50239863; o-Hydroxyphenylpyruvic acid lactone; ZINC336205; 2H-1-Benzopyran-2-one,3-hydroxy-; 3767AF; BDBM50206007; CCG-39664; MFCD00017490; NSC-74691; SBB056328; AKOS015916452; MCULE-4074896000; SDCCGMLS-0066523.P001; NCGC00095536-01; NCGC00095536-02; NCGC00178445-01; DB-057448; HY-127170; CS-0094421; FT-0633159; ST50331499; AN-829/40355682; BRD-K92019075-001-02-0; Q27194434
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| Activity |
IC50 = 131000 nM
|
[4] | |||
| Compound Name |
Butyric acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL94510; BDBM50131453; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-(butyryloxy)chroman-7,8-diol
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| Activity |
IC50 = 139000 nM
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[13] | |||
| Compound Name |
Acetic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL319287; BDBM50131451; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-acetoxychroman-7,8-diol
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| Activity |
IC50 = 150000 nM
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[13] | |||
| Compound Name |
(-)-6-Feruloyl-catalpol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL463912; BDBM50250502
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| Activity |
IC50 = 150400 nM
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[10] | |||
| Compound Name |
Octadecanoic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-7,8-dihydroxy-chroman-3-yl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL317730; BDBM50131449; (2S)-2beta-(3,4-Dihydroxyphenyl)-3alpha-(stearoyloxy)chroman-7,8-diol
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| Activity |
IC50 = 155750 nM
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[13] | |||
| Compound Name |
(2R,3R,4R,5R,6S)-2-[[(2R,3S,4S,5R,6S)-3,4-Dihydroxy-6-[3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenoxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methoxy]-6-methyloxane-3,4,5-triol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL501898; BDBM50259881
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| Activity |
IC50 = 178000 nM
|
[19] | |||
| Compound Name |
4-Hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
4-Coumarinol; 4-Hydroxy-2H-chromen-2-one; Benzotetronic acid; 2H-1-BENZOPYRAN-2-ONE, 4-HYDROXY-; Coumarin, 4-hydroxy-; 4-Hydroxy-2H-1-benzopyran-2-one; 4-hydroxychromen-2-one; 4-Hydroxy-chromen-2-one; 4-Hydroxy coumarin; MFCD00006856; 4-HYDROXY-1-BENZOPYRAN-2-ONE; 4-hydroxy-2-chromenone; UNII-X954ZLL2RD; 2-Hydroxychromone; 4-hydroxy-2H-benzo[b]pyran-2-one; 4-Hydroxycoumarin, 98%; 4H-1-Benzopyran-4-one, 2-hydroxy-; X954ZLL2RD; CHEMBL301141; NSC11889; 4-hydroxy-coumarin; EINECS 214-060-2; NSC 11889; BRN 0129768; hydroxychromone; AI3-52393; 4-hyroxycoumarin; 4- Hydroxycoumarin; 4-hydroxyl coumarin; 4-Monohydroxycoumarin; PubChem8693; ACMC-1BO7V; CBiol_000838; WLN: T66 BOVJ EQ; 5-18-01-00378 (Beilstein Handbook Reference); KSC175M9D; MLS004491719; SCHEMBL131312; Coumarin, 4-hydroxy- (8CI); MEGxm0_000452; SCHEMBL1961365; DTXSID8061472; ACon1_001952; CTK0H5691; 4-Hydroxy-2H-chromen-2-one #; DTXSID50944748; HMS1607G02; 4-hydroxy-2-oxo-2H-1-benzopyran; 2-Hydroxy-4H-1-benzopyran-4-one; BCP31120; HY-N6856; STR01861; ANW-15833; BBL027616; BDBM50055710; ICCB4_000134; NSC-11889; SBB038533; STK801816; ZINC18154848; ZINC96006086; AKOS000119142; AKOS037515220; AM84328; DB03410; EBD2035794; LS40467; MCULE-5951606896; NCGC00179970-01; AC-13227; AK-49238; NCI60_000453; SC-00282; SMR000112320; SY001614; AB0004657; DB-014485; BB 0220623; CS-0015925; EU-0066799; FT-0602218; FT-0660645; ST50211285; A-9316; C20414; 4-Hydroxycoumarin, Vetec(TM) reagent grade, 98%; SR-01000389319; J-515519; J-620003; SR-01000389319-1; 4-Hydroxy-2H-1-benzopyran-2-one (4-Hydroxycoumarin); BRD-K48844111-001-01-4; Q25323691; Z56922074; 4-HYDROXY-1-BENZOPYRAN-2-ONE; 4-HYDROXYCOUMARIN; F0266-2972; 4-Hydroxy Coumarin;4-Coumarinol;4-Hydroxy-2H-chromen-2-one
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| Activity |
IC50 = 195000 nM
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[4] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 55 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Nicotinamide
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Approved | Compound Info | ||
| Synonyms |
Aminicotin; Amixicotyn; Amnicotin; Benicot; Dipegyl; Endobion; Enduramide; Hansamid; Mediatric; Niacevit; Niacinamide; Niacotinamide; Niamide; Nicamina; Nicamindon; Nicasir; Nicobion; Nicofort; Nicogen; Nicomidol; Nicosylamide; Nicota; Nicotamide; Nicotilamide; Nicotililamido; Nicotinamid; Nicotinamida; Nicotinamidum; Nicotinsaeureamid; Nicotinsaureamid; Nicotol; Nicotylamide; Nicotylamidum; Nicovit; Nicovitina; Nicovitol; Nicozymin; Nikasan; Nikazan; Nikotinamid; Nikotinsaeureamid; Niocinamide; Niozymin; Papulex; Pelmin; Pelmine; Savacotyl; Amid kyseliny nikotinove; Amid kyseliny nikotinove [Czech]; Amide PP; Astra Brand of Niacinamide; Austrovit PP; Delonin amide; Factor pp; Inovitan PP; Jenapharm Brand of Niacinamide; Merck Brand of Niacinamide; Niacinamide Astra Brand; Niacinamide Jenapharm Brand; Niacinamide Merck Brand; Niacinamide Pharmagenix Brand; Niacinamide [USAN]; Niavit PP; Nicotine acid amide; Nicotine amide; Nicotinic acid amide; Nicotinic amide; Nicotinsaureamid Jenapharm; Nicotinsaureamid [German]; Nikotinsaeureamid [German]; Pelonin amide; Pharmagenix Brand of Niacinamide; Vitamin B; Vitamin PP; Witamina PP; Nicosan 2; Vitamin H1; B 3, Vitamin; B3, Vitamin; Beta-Pyridinecarboxamide; Jenapharm, Nicotinsaureamid; Nandervit-N; Niacin-Vitamin B3; Niacinamide (USP); Nicotinamida [INN-Spanish]; Nicotinamide (Niacinamide); Nicotinamidum [INN-Latin]; Niko-tamin; PP-Faktor; Vi-Nicotyl; Vitamin B (VAN); M-(Aminocarbonyl)pyridine; Niacinamide, Nicotinic acid amide, Nicotinamide; Nicotinamide (JP15/INN); Nicotinamide, niacin, vitamin B3; Nicotinamide-carbonyl-14C; Pyridine-3-carboxamide; Pyridine-3-carboxylic acid amide; 3 Pyridinecarboxamide; 3-Carbamoylpyridine; 3-Pyridinecarboxamide; 3-Pyridinecarboxylic acid amide
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| Activity |
IC50 = 518230 nM
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[21] | |||
| Compound Name |
Genistein
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Phase 2/3 | Compound Info | ||
| Synonyms |
Bonistein; GEN; Genestein; Genisteol; Genisterin; Prunetol; Sophoricol; Differenol A; G 6649; G10000; IN1327; NPI 031L; STO514; TNP00151; GENISTEIN (ENDOCRINE DISRUPTER); Lactoferrin-genistein; PTI G4660 (Genistein); PTI-G4660; SIPI 807-1; C.I. 75610; SIPI-9764-I; ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)); 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; ,5,7-Trihydroxyisoflavone; 4',5, 7-Trihydroxyisoflavone; 4',5,7-Trihydroxy isoflavone; 4',5,7-Trihydroxyisoflavone; 4,5,7-Trihydroxyiso-flavone; 4,6,7-Trihydroxyisoflavone; 5,7,4'-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
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| Activity |
IC50 = 232500 nM
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[22] | |||
| Compound Name |
Merbarone
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Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
NSC-336628
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| Activity |
IC50 = 274000 nM
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[23] | |||
| Compound Name |
1-METHYLXANTHINE
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Investigative | Compound Info | ||
| Synonyms |
1-Methylxanthine; 6136-37-4; 1-Methyl-3,7-dihydro-purine-2,6-dione; 1-Methyl-1H-purine-2,6(3H,7H)-dione; Methylxanthine; Xanthine, 1-methyl-; UNII-7EE8WCA32U; 2,6-Dihydroxy-1-methylpurine; CCRIS 5816; 1-methyl-7H-xanthine; EINECS 228-108-5; 1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-; 7EE8WCA32U; CHEMBL1250; 2,6 Dihydroxy-1-methylpurine; CHEBI:68444; 3,7-Dihydro-1-methyl-1H-purine-2,6-dione; MVOYJPOZRLFTCP-UHFFFAOYSA-N; 1-methyl-3,7-dihydropurine-2,6-dione; 1-methyl-3,9-dihydropurine-2,6-dione
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| Activity |
IC50 > 200000 nM
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[2] | |||
| Compound Name |
7-hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
Umbelliferone; 93-35-6; 7-Hydroxy-2H-chromen-2-one; Skimmetin; Hydrangin; 7-hydroxycoumarine; 7-Oxycoumarin; Umbelliferon; Skimmetine; Hydrangine; 2H-1-Benzopyran-2-one, 7-hydroxy-; 7-Hydroxy-2H-1-benzopyran-2-one; Coumarin, 7-hydroxy-; beta-Umbelliferone; 7-hydroxychromen-2-one; 7 HC; UNII-60Z60NTL4G; 7-hydroxy-coumarin; NSC 19790; CCRIS 3591; NSC19790; EINECS 202-240-3; 7H-1-Benzopyran-7-one, 2-hydroxy-; BRN 0127683; CHEMBL51628; AI3-38054; 7-hydroxy-1-benzopyran-2-one; 7-HC; 60Z60NTL4G; CHEBI:27510; UMBELLIFERONE
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| Activity |
IC50 = 236000 nM
|
[4] | |||
| Compound Name |
daidzein
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Investigative | Compound Info | ||
| Synonyms |
Daidzein; 486-66-8; 4',7-Dihydroxyisoflavone; Daidzeol; 7,4'-Dihydroxyisoflavone; 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-; 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one; 7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone; UNII-6287WC5J2L; CCRIS 7600; K 251b; 4,7-Dihydroxyisoflavone; EINECS 207-635-4; BRN 0231523; CHEMBL8145; 4',7-Dihydroxy-iso-flavone; d-(+)-alpha-methylbenzylamine; ,7-Dihydroxyisoflavone; 7,4'-dihydroxyisoflavone; DIADZEIN
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| Activity |
IC50 = 429800 nM
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[22] | |||
| Compound Name |
7,8,4'-trihydroxyisoflavone
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Investigative | Compound Info | ||
| Synonyms |
7,8,4'-Trihydroxyisoflavone; 8-Hydroxydaidzein; 75187-63-2; 4',7,8-Trihydroxyisoflavone; 7,8-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one; 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one; 7,8-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; NSC678112; CHEMBL242739; NSC 678112; 4H-1-Benzopyran-4-one, 7,8-dihydroxy-3-(4-hydroxyphenyl)-; 7,4'-Trihydroxyisoflavone; AC1NV1M1; SCHEMBL571127; 7,8,4''-trihydroxyisoflavone; 4'',7,8-trihydroxyisoflavone; CTK5E1244; DTXSID20226169; MolPort-000-165-583; BMZFZTMWBCFKSS-UHFFFAOYSA-N
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| Activity |
IC50 > 1000000 nM
|
[22] | |||
| Compound Name |
7,3',4'-trihydroxyisoflavone
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Investigative | Compound Info | ||
| Synonyms |
3',4',7-Trihydroxyisoflavone; 3'-Hydroxydaidzein; 485-63-2; 3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one; 7,3',4'-Trihydroxyisoflavone; UNII-T08Y239E7Y; CHEMBL13486; CHEBI:50399; 3',4',7-trihydroxy isoflavone; DDKGKOOLFLYZDL-UHFFFAOYSA-N; 3'',4'',7-trihydroxyisoflavone; T08Y239E7Y; 3-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one; 3-(3,4-dihydroxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 3-(3,4-dihydroxyphenyl)-7-hydroxy-; 47X; Orita-13; 3l5r; AC1NR4TZ; SCHEMBL73012; BIDD:ER0118; GTPL9985
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| Activity |
IC50 > 1000000 nM
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[22] | |||
| Compound Name |
2-Amino-6-chloropurine
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Investigative | Compound Info | ||
| Synonyms |
6-Chloroguanine; 6-Chloro-9H-purin-2-amine; 6-chloro-7H-purin-2-amine; 6-Chloro-2-aminopurine; 2-Amino-6-chlorpurine; 2-Amino-6-Chloro-Purin; 1H-Purin-2-amine, 6-chloro-; Purine, 2-amino-6-chloro-; 6-Chloro-7H-purin-2-ylamine; MFCD00075252; 2-amino-6-chloro-purine; 2-Amino-6-chloropurin-9-yl; UNII-83V03P835E; 9H-Purin-2-amine, 6-chloro-; 2-amino-6-chloro purine; 6-chloro-2-amino-purine; 2-amino-6-chloro-9h-purine; 6-chloro-9h-purin-2-ylamine; CHEMBL226396; 83V03P835E; 2-Amino-6-chloropurine (6-Chloroguanine); 6-chloropurine-2-ylamine; 2-Amino-6-chloropurine, 99+%; 6-CHLORO-1H-PURIN-2-AMINE; EINECS 233-686-7; NSC 29570; CCRIS 3906; aurora ka-689; zlchem 325; PubChem9187; 2-amino-6chloropurine; 6-Cl-purine (1); 6-Chloro-2-purinamine; bmse000984; SCHEMBL6711; KSC174S0H; MLS006011426; 6-chloro-1H-purine-2-amine; Famciclovir Related Compound F; ACMC-20984h; 2-Amino-6-chloropurine, 97%; DTXSID9074432; 6-Chloro-9H-purin-2-amine #; CTK0H4903; CTK7E0696; ZLC0159; AM677; 2-Amino-6-chloropurine, >=99%; ACT02228; ALBB-023676; BCP27028; CS-D1374; KS-00000A0D; NSC29570; ZINC6523923; AB2611; ANW-14799; BBL010748; BDBM50208877; NSC-29570; SBB003863; STK801756; AKOS000266285; AKOS005622720; AKOS028108866; AC-5457; AS-2051; LS20596; MCULE-7459126915; 1H-Purin-2-amine, 6-chloro- (9CI); AK-23601; BR-23601; SC-00127; SMR002529527; SY001781; AB0008352; DB-005179; FT-0600035; ST45026866; 6-Chloro-7H-purin-2-ylamine; 6-Chloroguanine; M-2830; X-2170; 310A211; SR-01000944797; Q-200234; SR-01000944797-1; Q27139921; 9-n-Butyl-1,2,3,4,5,6,7,8-octahydroacridin-4-ol; F0001-0084; Z2723701924
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| Activity |
IC50 > 200000 nM
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[2] | |||
| Compound Name |
2,6-Diaminopurine
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Investigative | Compound Info | ||
| Synonyms |
9H-Purine-2,6-diamine; 2-Aminoadenine; 7H-purine-2,6-diamine; 1H-Purine-2,6-diamine; 2,6-diamino-9h-purine; Purine, 2,6-diamino-; NSC 743; SQ 21065; 26-diaminopurine; 2,6-Diamino-purin-9-yl; 2,6-Diaminopurine, 98%; UNII-49P95BAU4Z; purine-2,6-diamine; 49P95BAU4Z; CHEMBL388596; MFCD00213668; Purine-2,6-diyldiamine; CCRIS 923; EINECS 217-605-2; AI3-25010; CCRIS 3903; 2-6-Diaminopurine; Purine,6-diamino-; 2,6-diamino-purine; PubChem9203; Purine, 2, 6-diamino-; Oprea1_670021; SCHEMBL24052; 9H-Purine-2,6-diamine #; KSC179A1B; MLS001066366; NSC743; DTXSID0062052; SCHEMBL16513167; CTK0H9010; CTK7E0750; NSC-743; (2-amino-7H-purin-6-yl)-amine; HMS2267N10; ALBB-023319; BCP30955; ZINC7486121; ANW-23487; BDBM50208879; MFCD00047146; MFCD00071537; SBB000103; AKOS003368184; AKOS015896933; AKOS028109333; 9H-Purine-2,6-diamine0.5M H2SO4; AC-8693; AM81387; GS-3048; LS20247; MCULE-1333744381; 9H-Purine-2,6-diamine;2-Aminoadenine; AK-68382; BP-13206; SC-02056; SMR000112503; ST012425; SY036886; TS-00060; AB0010986; DB-015922; D1625; FT-0610530; S-8021; 904D989; AC-907/34116038; Q-200204; Q4596802; W-203543
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| Activity |
IC50 > 200000 nM
|
[2] | |||
| Compound Name |
5,6-Dimethylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
5,6-Dimethyl-1H-benzimidazole; Dimedazol; Dimedazole; 5,6-dimethyl-1H-benzo[d]imidazole; Dimesol; dimethylbenzimidazole; Dimezol; 1H-Benzimidazole, 5,6-dimethyl-; 5.6-Dimethylbenzimidazole; Benzimidazole, 5,6-dimethyl-; 5,6-Dimethyl Benzimidazole; NSC 68316; UNII-553XI1DS20; 5,6-dimethyl-1H-benzoimidazole; 5,6-dimethylbenzimidazol; MFCD00005603; CHEMBL351132; 553XI1DS20; 5,6-Dimethylbenzimidazole, 99+%; EINECS 209-488-1; BRN 0116595; DimezolDimedazol; Dimezol base; AI3-52806; Dimezol (VAN); PubChem7550; ACMC-1ALRI; Benzimidazole,6-dimethyl-; 5,6-dimethylbenzoimidazole; bmse000881; 5-23-06-00454 (Beilstein Handbook Reference); KSC269G6H; SCHEMBL312977; 1H-Benzimidazole,6-dimethyl-; 5,6-dimethylbenzo[d]imidazole; ARONIS001284; SCHEMBL3893948; CTK1G9363; KS-00000JIQ; DTXSID70870631; HMS1659L03; ZINC388593; ALBB-021295; KS-00003US8; NSC68316; 5,6-dimethyl-1H-1,3-benzodiazole; 5,6-Dimethylbenzimidazole, >=99%; ANW-32902; BBL023511; BDBM50208872; NSC-68316; s3097; SBB004105; STK001228; 5,6-dimethyl-1H-1,3-benzimidazole; AKOS000121551; AC-8359; CS-W018227; DB02591; HY-W017511; MCULE-3421723513; VI10159; AK-78911; AS-10901; SC-05507; AM20040774; BB 0241929; D1345; FT-0619833; ST45038102; C03114; L-1289; AB00375938-02; 5,6-Dimethylbenzimidazole, purum, >=99.0% (NT); Q-100667; Q15269676; F3145-1021; B97E9041-BA87-4952-8BE7-E80B4E480262
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| Activity |
IC50 > 200000 nM
|
[2] | |||
| Compound Name |
5-Methylbenzimidazole
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Investigative | Compound Info | ||
| Synonyms |
5-methyl-1H-benzo[d]imidazole; 5-methyl-1H-benzimidazole; 1H-Benzimidazole, 5-methyl-; 6-methyl-1H-benzimidazole; 5-methyl-1H-1,3-benzodiazole; BENZIMIDAZOLE, 5-METHYL-; 1H-Benzimidazole, 6-methyl-; MFCD00010740; UNII-R56855UC8Y; CHEMBL157729; R56855UC8Y; ethyl 4-cyanophenylalaninate; NSC 3826; EINECS 210-401-4; 6-Methylbenzimidazol; 5-methylbenzoimidazole; PubChem7666; ACMC-1BEHW; 5(6)-Methylbenzimidazole; 5-methyl-1H-benzoimidazole; SCHEMBL10903; 5-Methylbenzimidazole, 98%; BIDD:GT0671; 6-methyl-1H-1,3-benzodiazole; DTXSID1060639; CTK3J3270; WLN: T56 BM DNJ G1; NSC3826; ALBB-028791; NSC-3826; ZINC5988533; ANW-33835; ANW-45816; BBL015760; BDBM50208880; SBB046249; STK242092; phenylalanine, 4-cyano-, ethyl ester; AKOS000275603; AKOS015953401; AC-2010; ACN-050882; DB03177; GS-6306; MCULE-9032121446; VI10184; AK-87161; Benzimidazole, 5(or 6)-methyl- (7CI); SY037745; DB-017454; BB 0219447; FT-0620642; M1321; ST45021926; L-4171; 614M971; W-105148; Q27094112; F2163-0011
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| Activity |
IC50 > 200000 nM
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[2] | |||
| Compound Name |
2-Aminopurine
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Investigative | Compound Info | ||
| Synonyms |
7H-purin-2-amine; 1H-PURIN-2-AMINE; 9H-Purin-2-amine; Purine, 2-amino-; Aminopurine; SQ 22451; 2-amino purine; 2'-amino-purine; UNII-O14B3U97FW; 7H-Purin-2-ylamine; 9H-Purin-2-ylamine; SQ 22,451; CHEMBL388594; O14B3U97FW; purine-2-ylamine; NSC24129; MFCD00005566; Isoadenine; SMR000857109; CCRIS 759; EINECS 207-197-4; NSC 24129; Citronellylcinnamate; 3h-purin-2-amine; PubChem9263; 2-Aminopurine, 98%; 9H-Purin-2-amine #; BiomolKI_000044; ACMC-1AD7C; BiomolKI2_000050; 2-Aminopurine, >=99%; SCHEMBL5631; BMK1-E8; MLS001333095; MLS001333096; Famciclovir Related Compound E; CTK0H1446; CTK1D6989; CTK2D5379; CTK7E1173; KS-00000JXS; DTXSID40196416; HMS2230L13; HMS3373E01; BCP32824; 2H-Purin-2-imine, 1,9-dihydro-; ANW-30225; BDBM50208875; NSC-24129; SBB052105; ZINC18544062; AKOS006220998; AKOS015961157; ACN-048436; CCG-100648; CS-W013358; SDCCGMLS-0065821.P001; NCGC00163382-01; AC-13347; AK110992; SC-52862; TS-00023; DB-008162; FT-0611268; ST50298872; 148205-EP2289893A1; 452A062; Q209313; W-202796
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| Activity |
IC50 > 200000 nM
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[2] | |||
| Compound Name |
2-Amino-6-methoxypurine
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Investigative | Compound Info | ||
| Synonyms |
6-Methoxyguanine; O6-Methylguanine; 6-methoxy-9H-purin-2-amine; 6-O-Methylguanine; 6-Methoxy-7H-purin-2-amine; O-(6)-Methylguanine; 1H-Purin-2-amine, 6-methoxy-; Purine, 2-amino-6-methoxy-; 6-Methoxy-1H-purine-2-amine; O(sup 6)-Methylguanine; UNII-9B710FV2AE; 6-METHOXY-1H-PURIN-2-AMINE; MFCD00133009; 9B710FV2AE; CHEMBL226395; NSC37364; 9H-PURIN-2-AMINE, 6-METHOXY-; 6-methoxypurine-2-ylamine; O(6)-methylguanine; NSC 37364; O-Methylguanine; PubChem9244; ACMC-209fbs; O6-MeG; 2-amino-6-methoxy purine; NCIMech_000186; 6-O-Methylguanine, 97%; DSSTox_CID_29365; DSSTox_RID_83480; DSSTox_GSID_49405; MLS001074870; SCHEMBL231097; BDBM5470; DTXSID9049405; CTK7B2040; CTK8B1153; 6-Methoxy-7H-purin-2-amine #; O6-Substituted Guanine Deriv. 1; HMS2231D13; HMS3370E06; BCP30956; ZINC4770610; Tox21_202966; ANW-24134; BBL101282; CCG-35441; NSC-37364; SBB052058; STL555078; AKOS005257755; AKOS015914255; Purine, 2-amino-6-methoxy- (8CI); CS-W014307; LS20599; MB00722; MCULE-4539018382; KS-000011U3; NCGC00247006-01; NCGC00260512-01; NCI60_003482; SC-46314; SMR000568400; SY036172; TS-00127; 2-Amino-6-methoxypurine;6-O-Methylguanine; DB-045270; A1151; FT-0638008; FT-0671802; ST50298900; 6-O-Methylguanine (2-Amino-6-Methoxypurine); 535A835; A814660; Q4641549; W-201791; BRD-K99514692-001-06-7
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| Activity |
IC50 > 200000 nM
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[2] | |||
| Compound Name |
Secoisolariciresinol
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Investigative | Compound Info | ||
| Synonyms |
(-)-Secoisolariciresinol; UNII-M8QRJ7JEJH; CCRIS 7790; M8QRJ7JEJH; EINECS 249-599-2; (2R,3R)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol; CHEMBL368347; (2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butane-1,4-diol; (R-(R*,R*))-2,3-Bis((4-hydroxy-3-methoxyphenyl)methyl)butane-1,4-diol; RR-secoisolariciresinol; (-) secoisolariciresinol; (+/-)-Secoisolariciresinol; 8R,8'R-secoisolariciresinol; MLS001424213; SCHEMBL12427083; CTK4C5737; DTXSID50183615; HMS2052G03; HMS2232J05; (2R*,3R*)-2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediol; HY-N6071; ZINC2020114; BDBM50240914; MFCD01075136; AKOS032948353; CCG-101074; DB12179; NC00324; NCGC00346838-01; Secoisolariciresinol, >=95.0% (HPLC); SMR000469212; LS-185231; CS-0032316; C18167; Q-100372; Q4413253; 2,3-Bis(4-hydroxy-3-methoxybenzyl)-1,4-butanediol, (-); (2R,3R)-2,3-bis[(4-hydroxy-3-methoxy-phenyl)methyl]butane-1,4-diol
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| Activity |
IC50 = 213000 nM
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[10] | |||
| Compound Name |
4-Methylesculetin
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Investigative | Compound Info | ||
| Synonyms |
6,7-DIHYDROXY-4-METHYLCOUMARIN; 6,7-Dihydroxy-4-methyl-2H-chromen-2-one; Methylesculetin; 4-Methylaesculetin; 4-Methylesculetol; 4-Methyl-6,7-dihydroxycoumarin; 6,7-dihydroxy-4-methylchromen-2-one; 6,7-Dihydroxy-4-methyl-2H-benzopyran-2-one; 2H-1-Benzopyran-2-one, 6,7-dihydroxy-4-methyl-; Coumarin, 6,7-dihydroxy-4-methyl-; NSC 11828; NSC 688807; UNII-132H8N0A91; 6,7-Dihydroxy-4-methyl-2H-1-benzopyran-2-one; 6,7-Dihydroxy-4-methyl-chromen-2-one; CHEMBL313244; NSC11828; MFCD00006859; NSC688807; 132H8N0A91; NSC-688807; SR-01000389898; EINECS 208-470-0; BRN 0162550; AI3-18220; Spectrum_001029; SpecPlus_000495; Spectrum2_000617; Spectrum3_000592; Spectrum4_001864; Spectrum5_000428; Oprea1_739367; BSPBio_002064; KBioGR_002330; KBioSS_001509; 5-18-03-00231 (Beilstein Handbook Reference); DivK1c_006591; SCHEMBL409482; SPECTRUM1500729; SPBio_000554; DTXSID6060187; 4-methy1-6,7-dihydroxycoumarin; KBio1_001535; KBio2_001509; KBio2_004077; KBio2_006645; KBio3_001564; ZINC58125; ALBB-015650; HY-N4288; KS-000013XH; 7498AB; ANW-43466; BBL027618; BDBM50078820; CCG-38534; NSC-11828; s4966; SBB057778; STL372185; AKOS003241110; GS-5460; MCULE-2984770490; SDCCGMLS-0066617.P001; NCGC00095628-01; NCGC00095628-02; NCGC00178836-01; 4-methyl-6,7-bis(oxidanyl)chromen-2-one; DB-052228; 6,7-dihydroxy-4-methyl-1-benzopyran-2-one; CS-0032643; EU-0066858; FT-0619082; M0766; R1156; ST45024832; A829333; SR-01000389898-1; SR-01000389898-2; W-200029; Q27251461; F1011-0383
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| Activity |
IC50 = 246000 nM
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[4] | |||
| Compound Name |
5-Pyrimidinecarboxamide, hexahydro-2,4,6-trioxo-N-phenyl-
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Investigative | Compound Info | ||
| Synonyms |
NSC366236; UPDDI-00294852; 6-hydroxy-2,4-dioxo-N-phenyl-1H-pyrimidine-5-carboxamide; NSC 366236; BRN 0809773; 2,4,6-Trioxohexahydro-5-pyrimidinecarboxanilide; CC-PMLSC-PW-kmc1025; MLS000541789; cid_100782; CHEMBL2164432; CHEMBL2362597; SCHEMBL10926831; BDBM46100; DTXSID50997592; HMS2211H20; HMS3332H09; ZINC1586033; 5-Pyrimidinecarboxanilide, 1,2,3,4,5,6-hexahydro-2,4,6-trioxo-; ZINC 1586033; AKOS015952824; US9428466, 2-oxo-desthiomerbarone; NSC-366236; NCGC00247368-01; SMR000472445; 5-Pyrimidinecarboxamide,4,6-trioxo-N-phenyl-; 5-25-08-00371 (Beilstein Handbook Reference); 2,4,6-Trihydroxy-N-phenyl-5-pyrimidinecarboxamide; 2,4,6-trihydroxy-N-phenyl-pyrimidine-5-carboxamide; N-Phenyl-2,4,6-trihydroxypyrimidine-5-carboxamide; 6-hydroxy-2,4-diketo-N-phenyl-1H-pyrimidine-5-carboxamide; 4,6-Dihydroxy-2-oxo-N-phenyl-1,2-dihydropyrimidine-5-carboxamide; 5-[Hydroxy(phenylamino)methylene]pyrimidine-2,4,6(1H,3H,5H)-trione; 6-oxidanyl-2,4-bis(oxidanylidene)-N-phenyl-1H-pyrimidine-5-carboxamide
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| Activity |
IC50 > 300000 nM
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[23] | |||
| Compound Name |
Daphnetin
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Investigative | Compound Info | ||
| Synonyms |
7,8-Dihydroxycoumarin; Daphnetol; 7,8-Dihydroxy-2H-chromen-2-one; 7,8-Dihydroxy-2H-1-benzopyran-2-one; 7,8-dihydroxychromen-2-one; 2H-1-Benzopyran-2-one, 7,8-dihydroxy-; 7,8-DIHYDROXY-2H-BENZOPYRAN-2-ONE; UNII-XC84571RD2; TCMDC-125839; COUMARIN, 7,8-DIHYDROXY-; CHEMBL244948; XC84571RD2; 7,8-Dihydroxycoumarin (Daphnetin); MFCD00016977; NSC633563; 7,8-DIHYDROXY-CHROMEN-2-ONE; SMR001230713; SR-01000075820; EINECS 207-632-8; NSC 633563; BRN 0009372; 1,8-Dihydroxycoumarin; PubChem13303; 7,8-dihydroxy-coumarin; ACMC-1AKCA; SpecPlus_000864; Spectrum3_000784; Spectrum4_001254; Lopac-D-5564; Lopac0_000330; Oprea1_044324; BSPBio_002488; KBioGR_001808; 5-18-03-00211 (Beilstein Handbook Reference); MLS002153288; MLS006012039; DivK1c_006960; SCHEMBL128212; 7,8-Dihydroxycoumarin, 90%; CTK1D5894; KBio1_001904; KBio3_001708; ZINC57753; 7,8-bis(oxidanyl)chromen-2-one; DTXSID00197560; HMS3261A21; HMS3656G16; 7,8-dihydroxy-1-benzopyran-2-one; HY-N0281; Tox21_500330; ANW-43482; BBL036425; BDBM50206006; CCG-39736; CD0136; HSCI1_000053; s2554; STL558976; 7,8-Dihydroxy-2H-chromen-2-one #; AKOS000277449; LP00330; MCULE-9549774136; NSC-633563; PB17055; SDCCGSBI-0050318.P003; KS-0000122Z; 7,8-Dihydroxycoumarin, >=97%, powder; NCGC00015349-01; NCGC00015349-02; NCGC00015349-03; NCGC00015349-04; NCGC00015349-05; NCGC00015349-06; NCGC00015349-12; NCGC00093770-01; NCGC00093770-02; NCGC00261015-01; AK170408; AS-63138; SC-13560; DB-051567; CS-0008778; D4001; EU-0000106; EU-0100330; FT-0603132; N1567; ST50308908; SW000346-2; V0328; C03093; D 5564; Q-1224; 2H-1-Benzopyran-2-one, 7,8-dihydroxy- (9CI); 486D351; A827573; AE-641/02519040; Q-100543; SR-01000075820-1; SR-01000075820-2; BRD-K61269089-001-01-4; BRD-K61269089-001-02-2; Q27102315
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| Activity |
IC50 = 390000 nM
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[4] | |||
| Compound Name |
Butylhydroxyanisole
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Investigative | Compound Info | ||
| Synonyms |
2(3)-tert-Butyl-4-methoxyphenol; Embanox; 2-tert-butyl-4-methoxyphenol;3-tert-butyl-4-methoxyphenol; Protex; Antioxyne B; tert-Butyl-4-methoxyphenol; (1,1-Dimethylethyl)-4-methoxyphenol; UNII-REK4960K2U; SCHEMBL30330; REK4960K2U; 2(3)-t-butyl-4-methoxyphenol; CHEMBL4296740; 2-tert-butyl-4-methoxyphenol; 3-tert-butyl-4-methoxyphenol; HY-B1066; CS-4622; SY010820; Q409401; Butylated Hydroxyanisole 500 microg/mL in Methanol; tert-Butyl-4-hydroxyanisole (mixture of 2- and 3-isomer); 2-(tert-Butyl)-4-methoxyphenol compound with 3-(tert-butyl)-4-methoxyphenol
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| Activity |
IC50 = 591000 nM
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[19] | |||
| Compound Name |
(3R,4R)-4,8-Dihydroxy-3-((R)-2-hydroxypentyl)-6,7-dimethoxyisochroman-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL488848; BDBM50335903; Q27138493; (3R,4R)-4,8-dihydroxy-3-((R)-2-hydroxypentyl)-6,7-dimethoxy-3,4-dihydroisochromen-1-one; 4alpha,8-Dihydroxy-6,7-dimethoxy-3alpha-[(R)-2-hydroxypentyl]-3,4-dihydro-1H-2-benzopyran-1-one
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| Activity |
IC50 > 612000 nM
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[24] | |||
| Compound Name |
Propyl gallate
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Investigative | Compound Info | ||
| Synonyms |
Propyl 3,4,5-trihydroxybenzoate; N-Propyl gallate; Tenox PG; Progallin P; Gallic acid, propyl ester; Nipagallin P; Gallic acid propyl ester; NIPA 49; Benzoic acid, 3,4,5-trihydroxy-, propyl ester; 3,4,5-Trihydroxybenzene-1-propylcarboxylate; n-Propyl 3,4,5-trihydroxybenzoate; 3,4,5-Trihydroxybenzoic acid propyl ester; Gallic acid n-propyl ester; Propylester kyseliny gallove; n-Propyl ester of 3,4,5-trihydroxybenzoic acid; FEMA No. 2947; NSC 2626; 3,4,5-Trihydroxybenzoic acid, propyl ester; NCI-C505888; 3,4,5-Trihydroxybenzoic acid n-propyl ester; UNII-8D4SNN7V92; Nipanox S 1; Propyl gallate (NF); Propyl gallate [NF]; Propyl gallate, 98%; MFCD00002196; CHEMBL7983; Gallic acid, n-propyl ester; 8D4SNN7V92; NSC2626; NSC-2626; NCGC00164234-01; DSSTox_CID_1201; DSSTox_RID_76009; DSSTox_GSID_21201; Gallate, Propyl; Pro gallin P; CCRIS 541; HSDB 591; n-Propyl-3,4,5-Trihydroxybenzoate; EINECS 204-498-2; Propylester kyseliny gallove [Czech]; Propyl galiate; AI3-17136; n-propyl-gallate; Sustane PG; n-Propyl gallate; Propylgallate,(S); Propyl Gallate FCC; Propyl gallate, powder; ACMC-209ahq; Gallic acid-propyl ester; 3,4,5-Trihydroxy-benzoic acid propyl ester; Oprea1_580415; SCHEMBL22630; CBDivE_013134; KSC175K3P; BIDD:ER0334; Propyl 3,5-trihydroxybenzoate; WLN: QR BQ CQ EVO3; INS NO.310; DTXSID5021201; CTK0H5537; FEMA 2947; KS-00000GZF; n-Propyl 3,5-trihydroxybenzoate; Propyl gallate, >=98%, FCC; INS-310; NCI-C50588; BCP13340; HY-N0524; ZINC1532172; Tox21_113531; Tox21_202286; Tox21_300060; ANW-17868; BDBM50032154; CP0103; s5113; SBB060377; AKOS001603853; ANGC-121-79-9; 5-Methyl-4,5-dihydrothiazole-2-thiol; CCG-207932; DB12450; MCULE-2693876364; NCGC00164234-02; NCGC00164234-03; NCGC00164234-04; NCGC00254138-01; NCGC00259835-01; 3,5-Trihydroxybenzene-1-propylcarboxylate; 3,5-Trihydroxybenzoic acid, propyl ester; AC-11365; AK-94176; AS-11986; NCI60_002094; Propyl gallate, USP, 98.0-102.0%; SC-19600; DB-003766; Benzoic acid,4,5-trihydroxy-, propyl ester; CS-0009059; E-310; EU-0036319; FT-0626599; G0018; ST50307922; n-Propyl ester of 3,5-trihydroxybenzoic acid; A19435; C11155; D02382; J10100; M-5795; Propyl gallate, antioxidant, >=98.0% (HPLC); Q608726; SR-01000944710; Propyl gallate, for microscopy, >=98.0% (HPLC); Q-201634; SR-01000944710-1; EFFF5FFA-651C-4DE3-A25F-D807C65D5537
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| Activity |
IC50 = 628000 nM
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[19] | |||
| Compound Name |
Fusarentin 6,7-dimethyl ether
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Investigative | Compound Info | ||
| Synonyms |
Fusarentin 6,7-Dimethylether; CHEMBL1668327; BDBM50335901; Q27138491; 8-Hydroxy-6,7-dimethoxy-3alpha-[(S)-2-hydroxypentyl]-3,4-dihydro-1H-2-benzopyran-1-one
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| Activity |
IC50 > 644000 nM
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[24] | |||
| Compound Name |
Monocerin
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Investigative | Compound Info | ||
| Synonyms |
UNII-G7C424U3DJ; CHEMBL488513; G7C424U3DJ; MEGxm0_000272; ACon0_000652; ACon1_001243; CTK8E0274; DTXSID70184361; ZINC4098447; BDBM50335899; MFCD08274586; AKOS030213206; NCGC00169540-01; C09953; Q2899189; BRD-K31616759-001-01-2
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| Activity |
IC50 > 648000 nM
|
[24] | |||
| Compound Name |
Colletotrialide, (+)-
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Investigative | Compound Info | ||
| Synonyms |
Colletotrialide; CHEMBL1668329; BDBM50335904; Q27138494; 3alpha-(3-Oxohexyl)-5,6-dimethoxy-7-hydroxyisobenzofuran-1(3H)-one
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| Activity |
IC50 > 648000 nM
|
[24] | |||
| Compound Name |
Fusarentin 6-Methyl Ether
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1668328; BDBM50335902; Q27138492; 7,8-Dihydroxy-6-methoxy-3alpha-[(S)-2-hydroxypentyl]-3,4-dihydro-1H-2-benzopyran-1-one
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| Activity |
IC50 > 675000 nM
|
[24] | |||
| Compound Name |
(2S,3Ar,9bR)-6,7-dihydroxy-8-methoxy-2-propyl-3,3a-dihydro-2H-furo[3,2-c]isochromen-5(9bH)-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1668326; 7?O?demethylmonocerin; BDBM50335900; Q27138489
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| Activity |
IC50 > 679000 nM
|
[24] | |||
| Compound Name |
Glycitein
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Investigative | Compound Info | ||
| Synonyms |
7,4'-Dihydroxy-6-methoxyisoflavone; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-; 4',7-Dihydroxy-6-methoxyisoflavone; UNII-92M5F28TVF; 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one; 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; 92M5F28TVF; CHEMBL513024; SCHEMBL19720; BIDD:ER0470; Glycitein, analytical standard; Glycitein, >=97% (HPLC); CTK8E8802; DTXSID40193960; HMS3886N16; BCP13270; HY-N0016; ZINC5999205; AC-998; BDBM50241530; LMPK12050104; s9107; SBB065744; AKOS015892762; CCG-267294; KS-00000I04; AK198738; AS-71538; AB0073031; DB-049688; FT-0630616; N1785; ST50331727; A12064; C14536; 957G833; A825364; Q-100465; Q3109347; 3-(4-hydroxyphenyl)-6-methoxy-7-oxidanyl-chromen-4-one; 4-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one; 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4H-one; UNII-71B37NR06D component DXYUAIFZCFRPTH-UHFFFAOYSA-N; 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-1-benzopyran-4-one; Glycitein, United States Pharmacopeia (USP) Reference Standard
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||||
| Activity |
IC50 = 682600 nM
|
[22] | |||
| Compound Name |
Trolox
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Investigative | Compound Info | ||
| Synonyms |
6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; TROLOX C; 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid; 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid; 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-; MFCD00006846; (+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid; Trolox(R), 97%; 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid; 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromene-2-carboxylic acid; 6-hydroxy-2,5,7,8-tetramethyl-chromane-2-carboxylic acid; EINECS 258-422-8; BRN 5052542; Trolox?; Trolox(TM); Prestwick_855; ACMC-20apju; ACMC-1ATBW; Prestwick0_000530; Prestwick1_000530; Prestwick2_000530; Prestwick3_000530; CHEMBL153; SCHEMBL3226; Oprea1_727377; BSPBio_000519; MLS002153860; SPBio_002440; BPBio1_000571; CTK1H0082; DTXSID60866306; HMS1569J21; HMS2096J21; HMS2230A15; HMS3369E20; HMS3713J21; HMS3885K19; BCP16474; KS-000015YX; ANW-31653; BBL103047; BDBM50359629; GEO-03688; s3665; SBB005933; STL556856; 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid; AKOS015856256; CCG-207912; CS-8035; MCULE-8649288753; NCGC00179534-01; AK116067; AS-30121; SC-94697; SMR001233218; ST057520; DB-052268; DB-071631; HY-101445; FT-0621156; FT-0770514; Q245489; SR-01000841227; SR-01000841227-2; BRD-A17846016-001-03-0; BRD-A17846016-001-07-1; 6-hydroxy-2,5,7,8-tetramethychroman-2-carboxylic acid; 6-Hydroxy-2,5,7,8-tetramethyl-2-chromancarboxylic acid; 6-Hydroxy-2,5,7,8-tetramethyl-2-chromanecarboxylic acid #; 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid; (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)carboxylic acid; (+/-)- 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; (+/-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; (+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 97%; (S)-(-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLICACID; 2H-1-Benzopyran-2-carboxylicacid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-; 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzo-pyran-2-carboxylic Acid; 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic Acid;; 6-hydroxy-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
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||||
| Activity |
IC50 > 1000000 nM
|
[25] | |||
| Compound Name |
6,7,4'-Trihydroxyisoflavone
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Investigative | Compound Info | ||
| Synonyms |
4',6,7-Trihydroxyisoflavone; Demethyltexasin; 6-Hydroxydaidzein; 6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; Desmethylglycitein; 6,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one; UNII-PLM2K574GE; PLM2K574GE; 4',6,7-trihydroxy isoflavone; CHEMBL239156; 6,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one; Soybean factor 2; SCHEMBL73999; BIDD:ER0396; 4'',6,7-trihydroxyisoflavone; 4',6,7,-Trihydroxyisoflavone; 6,7,3''-trihydroxyisoflavone; 6,7,4''-trihydroxyisoflavone; DTXSID8022452; 4'',6,7,-trihydroxyisoflavone; ZINC391977; HY-N5072; 9345AA; BDBM50222303; LMPK12050102; MFCD00016953; AKOS015903112; AS-70375; DB-107895; CS-0032293; FT-0766207; ST50331734; C14314; 817T311; A1-01444; Q23055293; 6,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 9CI
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||||
| Activity |
IC50 > 1000000 nM
|
[22] | |||
| Compound Name |
(5-Hydroxy-1H-indol-2-yl)-[4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl]methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3956175; BDBM244079; US9428478, TG6-205-2
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||||
| Activity |
IC50 = 200000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(2-hydroxyphenyl)piperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3978208; SCHEMBL14247354; BDBM244065; TG2-171-1; US9428478, TG2-171-1
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||||
| Activity |
IC50 = 200000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(4-hydroxyphenyl)piperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3973255; SCHEMBL14247109; BDBM244067; US9428478, TG6-120-4
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||||
| Activity |
IC50 = 200000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(4-aminophenyl)piperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3972131; SCHEMBL15868569; BDBM244061; US9428478, TG6-144-2
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||||
| Activity |
IC50 = 200000000 nM
|
[26] | |||
| Compound Name |
(5-Ethyl-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3928588; SCHEMBL14247395; BDBM244078; US9428478, TG6-202
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|
||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
(6-Methoxy-1H-benzimidazol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3945910; SCHEMBL14247768; BDBM244084; US9428478, TG6-228
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(4-methoxyphenyl)-3-methylpiperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3913803; SCHEMBL14247183; BDBM244055; US9428478, TG6-140
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
(6-Fluoro-1H-benzimidazol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3894978; SCHEMBL14247344; BDBM244071; US9428478, TG6-179-3
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3909093; SCHEMBL15861648; BDBM244083; US9428478, TG6-227
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
1-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-(4-propan-2-ylanilino)ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3921756; SCHEMBL14247614; BDBM244056; US9428478, TG6-149
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-(3,4-Difluoroanilino)-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3911567; SCHEMBL14247280; BDBM244058; US9428478, TG6-158
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3918475; SCHEMBL15868596; BDBM244068; US9428478, TG6-205-1
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|
||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(2-aminophenyl)piperazin-1-yl]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3902230; SCHEMBL14247163; BDBM244066; TG2-181-1; US9428478, TG2-181-1
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||||
| Activity |
IC50 = 20000000000 nM
|
[26] | |||
| Compound Name |
1H-Indol-2-yl-[4-(4-methoxyphenyl)piperazin-1-yl]methanone
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Investigative | Compound Info | ||
| Synonyms |
1H-indol-2-yl[4-(4-methoxyphenyl)piperazin-1-yl]methanone; CHEMBL3931544; SCHEMBL14247364; BDBM244080; ZINC8138762; STK620209; AKOS005553678; MCULE-6745209481; US9428478, TG6-225
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
(5,6-Dimethoxy-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3971548; SCHEMBL14247248; BDBM244072; US9428478, TG6-181
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
1-[2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-1H-indol-5-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3962276; SCHEMBL14247424; BDBM244069; US9428478, TG6-161
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3954604; SCHEMBL15861607; BDBM244086; US9428478, TG6-236
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
1-[2-[4-(4-Ethoxyphenyl)piperazine-1-carbonyl]-1H-indol-5-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3930500; SCHEMBL15861712; BDBM244087; US9428478, TG6-238
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||||
| Activity |
IC50 = 20000000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3980488; SCHEMBL14247600; BDBM244054; TG2-150; US9428478, TG2-150
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-[4-(4-Propan-2-yloxyphenyl)piperazine-1-carbonyl]-3H-benzimidazole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3918530; SCHEMBL15868573; BDBM244092; US9428478, TG6-251-1
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||||
| Activity |
IC50 = 20000000000 nM
|
[26] | |||
| Compound Name |
2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-N-methyl-1H-indole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3940571; SCHEMBL14247288; BDBM244082; US9428478, TG6-223
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
7-Acetyl-3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1H-quinolin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3969051; SCHEMBL14247105; BDBM244088; US9428478, TG6-239
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||||
| Activity |
IC50 = 20000000000 nM
|
[26] | |||
| Compound Name |
1-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-(N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-4-propan-2-ylanilino)ethanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3897456; SCHEMBL15867152; BDBM244060; US9428478, TG6-143-2
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
Methyl 2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3964327; SCHEMBL15861811; BDBM244081; US9428478, TG6-222
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
2-(4-Acetylanilino)-1-[4-(4-ethoxyphenyl)piperazin-1-yl]ethanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3904813; SCHEMBL14247179; BDBM244057; US9428478, TG6-153
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Compound Name |
Methyl 1-(5-fluoro-1H-indole-2-carbonyl)-4-(4-methoxyphenyl)piperazine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4109345; BDBM244085; US9428478, TG6-235
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||||
| Activity |
IC50 > 20000000000 nM
|
[26] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 11 | Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem. 2008 Apr;43(4):771-80. | ||||
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| REF 15 | Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage. Bioorg Med Chem. 2009 May 1;17(9):3414-25. | ||||
| REF 16 | Discovery of xanthine oxidase inhibitors and/or alpha-glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2778-81. | ||||
| REF 17 | HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1315-21. | ||||
| REF 18 | An apigenin-derived xanthine oxidase inhibitor from Palhinhaea cernua. J Nat Prod. 2006 Jul;69(7):1089-91. | ||||
| REF 19 | Bioactive constituents from Boswellia papyrifera. J Nat Prod. 2005 Feb;68(2):189-93. | ||||
| REF 20 | Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2',5'-dialkoxylchalcones as cancer chemopreventive agents. Bioorg Med Chem. 2008 Aug 1;16(15):7270-6. | ||||
| REF 21 | Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies. Bioorg Med Chem. 2017 Apr 15;25(8):2351-2371. | ||||
| REF 22 | ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5006-9. | ||||
| REF 23 | US patent application no. 9428466B2, Methods for reducing uric acid levels using barbiturate derivatives | ||||
| REF 24 | Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp. J Nat Prod. 2011 Jan 28;74(1):79-81. | ||||
| REF 25 | Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill). Bioorg Med Chem Lett. 2007 May 1;17(9):2558-60. | ||||
| REF 26 | US patent application no. 9428478B2, Piperazine derivatives, compositions, and uses related thereto | ||||
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